Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-05-10
DOI
10.3389/fcell.2021.659654
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biochemical Signals Mediate the Crosstalk between Cartilage and Bone in Osteoarthritis
- (2020) Xuchang Zhou et al. Biomed Research International
- Disorganization of chondrocyte columns in the growth plate does not aggravate experimental osteoarthritis in mice
- (2020) Ana Lamuedra et al. Scientific Reports
- Changes in DNA methylation accompany changes in gene expression during chondrocyte hypertrophic differentiation in vitro
- (2020) Purva Singh et al. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
- Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel
- (2020) Shahrbanoo Jahangir et al. Stem Cell Research & Therapy
- Development of Modular, Dual-Perfused Osteochondral Constructs for Cartilage Repair
- (2019) Ethan L.H. Daley et al. TISSUE ENGINEERING PART C-METHODS
- Association between chondrocalcinosis and osteoarthritis: A systematic review and meta‐analysis
- (2019) Yilun Wang et al. International Journal of Rheumatic Diseases
- Nerve-growth-factor antibody for the treatment of osteoarthritis pain and chronic low back pain
- (2019) Martin Schmelz et al. PAIN
- siRNA therapeutics: a clinical reality
- (2019) Phei Er Saw et al. Science China-Life Sciences
- Microcracks in subchondral bone plate is linked to less cartilage damage
- (2019) M. Zarka et al. BONE
- SDF-1/CXCR4 axis coordinates crosstalk between subchondral bone and articular cartilage in osteoarthritis pathogenesis
- (2019) Han-Jun Qin et al. BONE
- Regulatory Effects and Interactions of the Wnt and OPG-RANKL-RANK Signaling at the Bone-Cartilage Interface in Osteoarthritis
- (2019) Béla Kovács et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Age-related histological changes in calcified cartilage and subchondral bone in femoral heads from healthy humans
- (2019) Andreas Wiggers Nielsen et al. BONE
- Osteoarthritis year in review 2019: genetics, genomics and epigenetics
- (2019) L.N. Reynard et al. OSTEOARTHRITIS AND CARTILAGE
- Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis
- (2018) Steven K Pregizer et al. ANNALS OF THE RHEUMATIC DISEASES
- Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
- (2018) Quanbo Ji et al. ANNALS OF THE RHEUMATIC DISEASES
- Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes
- (2018) Arthur Winer et al. MOLECULAR CANCER THERAPEUTICS
- High-Frequency Ultrasound Imaging of Tidemark In Vitro in Advanced Knee Osteoarthritis
- (2018) Yan-Ping Huang et al. ULTRASOUND IN MEDICINE AND BIOLOGY
- Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice
- (2018) Xiao Wang et al. Nature Communications
- Gefitinib for Epidermal Growth Factor Receptor Activated Osteoarthritis Subpopulation Treatment
- (2018) Heng Sun et al. EBioMedicine
- Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development
- (2018) Yong Gong et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- (2018) Spencer L James et al. LANCET
- YAP1 negatively regulates chondrocyte differentiation partly by activating the β-catenin signaling pathway
- (2017) Beining Yang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Solute transport at the interface of cartilage and subchondral bone plate: Effect of micro-architecture
- (2017) Behdad Pouran et al. JOURNAL OF BIOMECHANICS
- Osteoblast role in osteoarthritis pathogenesis
- (2017) Nicola Maruotti et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
- (2017) Ok Hee Jeon et al. NATURE MEDICINE
- Senescent cells: an emerging target for diseases of ageing
- (2017) Bennett G. Childs et al. NATURE REVIEWS DRUG DISCOVERY
- Intra-articular therapy with recombinant human GDF5 arrests disease progression and stimulates cartilage repair in the rat medial meniscus transection (MMT) model of osteoarthritis
- (2017) W.R. Parrish et al. OSTEOARTHRITIS AND CARTILAGE
- Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis
- (2017) Tristan W. Fowler et al. Scientific Reports
- Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
- (2017) Chiranjib Chakraborty et al. Molecular Therapy-Nucleic Acids
- Systemic neutralization of TGF-β attenuates osteoarthritis
- (2016) Liang Xie et al. Annals of the New York Academy of Sciences
- PKCδnull mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
- (2016) Ranjan Kc et al. ANNALS OF THE RHEUMATIC DISEASES
- THU0019 Age-Related Histological Changes in Calcified Cartilage and Subchondral Bone Plate in Complete Human Femoral Heads
- (2016) A.W. Nielsen et al. ANNALS OF THE RHEUMATIC DISEASES
- Neutral solute transport across osteochondral interface: A finite element approach
- (2016) Vahid Arbabi et al. JOURNAL OF BIOMECHANICS
- Inhibition of vascular endothelial growth factor with shRNA in chondrocytes ameliorates osteoarthritis
- (2016) Xufang Zhang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Role of the Subchondral Bone in Articular Cartilage Degeneration and Repair
- (2016) Henning Madry et al. JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
- Structural and mechanical properties of the proliferative zone of the developing murine growth plate cartilage assessed by atomic force microscopy
- (2016) Carina Prein et al. MATRIX BIOLOGY
- GDF5 modifies disease in OA rat model
- (2016) Jessica McHugh Nature Reviews Rheumatology
- Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage–bone crosstalk
- (2016) Steven R. Goldring et al. Nature Reviews Rheumatology
- Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis
- (2016) H. Iijima et al. OSTEOARTHRITIS AND CARTILAGE
- Efficacy and Safety of Tanezumab on Osteoarthritis Knee and Hip Pains: A Meta-Analysis of Randomized Controlled Trials
- (2016) Junyuan Chen et al. PAIN MEDICINE
- EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation
- (2016) Haoruo Jia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- When Is Osteonecrosis Not Osteonecrosis?: Adjudication of Reported Serious Adverse Joint Events in the Tanezumab Clinical Development Program
- (2016) Marc C. Hochberg et al. Arthritis & Rheumatology
- Emerging Targets for the Management of Osteoarthritis Pain
- (2016) Anne-Marie Malfait et al. Current Osteoporosis Reports
- Review Article: Osteophytes
- (2016) Siu Him Janus Wong et al. Journal of Orthopaedic Surgery
- Quantitative study on morphology of calcified cartilage zone in OARSI 0∼4 cartilage from osteoarthritic knees
- (2016) B. Deng et al. Current Research in Translational Medicine
- Tanezumab for Patients with Osteoarthritis of the Knee: A Meta-Analysis
- (2016) Shun-Li Kan et al. PLoS One
- Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
- (2015) Daniel L. Worthley et al. CELL
- Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies
- (2015) M.C. Hochberg OSTEOARTHRITIS AND CARTILAGE
- A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee
- (2015) T.J. Schnitzer et al. OSTEOARTHRITIS AND CARTILAGE
- Cell-based articular cartilage repair: the link between development and regeneration
- (2015) K.L. Caldwell et al. OSTEOARTHRITIS AND CARTILAGE
- Generalized Degenerative Joint Disease in Osteoprotegerin (Opg) Null Mutant Mice
- (2015) B. Bolon et al. VETERINARY PATHOLOGY
- A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis
- (2015) Andrew J. Barr et al. ARTHRITIS RESEARCH & THERAPY
- Pathology of the Calcified Zone of Articular Cartilage in Post-Traumatic Osteoarthritis in Rat Knees
- (2015) Melissa Schultz et al. PLoS One
- On fragmenting, densely mineralised acellular protrusions into articular cartilage and their possible role in osteoarthritis
- (2014) A. Boyde et al. JOURNAL OF ANATOMY
- Microstructural changes in cartilage and bone related to repetitive overloading in an equine athlete model
- (2014) Sean M. Turley et al. JOURNAL OF ANATOMY
- How best to preserve and reveal the structural intricacies of cartilaginous tissue
- (2014) Ernst B. Hunziker et al. MATRIX BIOLOGY
- Origin and function of cartilage stem/progenitor cells in osteoarthritis
- (2014) Yangzi Jiang et al. Nature Reviews Rheumatology
- Bone–cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategies
- (2014) X.L. Yuan et al. OSTEOARTHRITIS AND CARTILAGE
- Bone sialoprotein as a potential key factor implicated in the pathophysiology of osteoarthritis
- (2014) L. Pesesse et al. OSTEOARTHRITIS AND CARTILAGE
- Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis
- (2014) Toshihiro Nagai et al. ARTHRITIS RESEARCH & THERAPY
- Osteoblast-Chondrocyte Interactions in Osteoarthritis
- (2014) David M. Findlay et al. Current Osteoporosis Reports
- Circulating C reactive protein in osteoarthritis: a systematic review and meta-analysis
- (2013) Xingzhong Jin et al. ANNALS OF THE RHEUMATIC DISEASES
- Subchondral Bone Trabecular Integrity Predicts and Changes Concurrently With Radiographic and Magnetic Resonance Imaging-Determined Knee Osteoarthritis Progression
- (2013) Virginia Byers Kraus et al. ARTHRITIS AND RHEUMATISM
- Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
- (2013) Gehua Zhen et al. NATURE MEDICINE
- Impaired glycolytic metabolism causes chondrocyte hypertrophy-like changes via promotion of phospho-Smad1/5/8 translocation into nucleus
- (2013) T. Nishida et al. OSTEOARTHRITIS AND CARTILAGE
- Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes
- (2013) Brandon D Markway et al. ARTHRITIS RESEARCH & THERAPY
- Non-invasive imaging of cartilage in early osteoarthritis
- (2013) A. J. R. Palmer et al. Bone & Joint Journal
- Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice
- (2012) J Bertrand et al. ANNALS OF THE RHEUMATIC DISEASES
- Neuroplasticity of sensory and sympathetic nerve fibers in a mouse model of a painful arthritic joint
- (2012) Joseph R. Ghilardi et al. ARTHRITIS AND RHEUMATISM
- Zone-specific gene expression patterns in articular cartilage
- (2012) Shawn P. Grogan et al. ARTHRITIS AND RHEUMATISM
- Aging processes and the development of osteoarthritis
- (2012) Richard F. Loeser CURRENT OPINION IN RHEUMATOLOGY
- Analysis of the Mineral Composition of the Human Calcified Cartilage Zone
- (2012) Ying Zhang et al. International Journal of Medical Sciences
- A multi-modal multiphoton investigation of microstructure in the deep zone and calcified cartilage
- (2012) Jessica C. Mansfield et al. JOURNAL OF ANATOMY
- Consider the Tidemark
- (2012) P. A. SIMKIN JOURNAL OF RHEUMATOLOGY
- Bone remodelling in osteoarthritis
- (2012) David B. Burr et al. Nature Reviews Rheumatology
- Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis
- (2012) Paul I. Mapp et al. Nature Reviews Rheumatology
- New findings in osteoarthritis pathogenesis: therapeutic implications
- (2012) Lia Pulsatelli et al. Therapeutic Advances in Chronic Disease
- Study of the tidemark in human mandibular condylar cartilage
- (2011) R. Chen et al. ARCHIVES OF ORAL BIOLOGY
- Osteochondral alterations in osteoarthritis
- (2011) Sunita Suri et al. BONE
- New Hope for the Treatment of Osteoarthritis Through Selective Inhibition of MMP-13
- (2011) N.-G. Li et al. CURRENT MEDICINAL CHEMISTRY
- The Critical Role of the Epidermal Growth Factor Receptor in Endochondral Ossification
- (2011) Xianrong Zhang et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification
- (2011) E J Mackie et al. JOURNAL OF ENDOCRINOLOGY
- Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?
- (2011) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- The expression of RANKL and OPG in the various grades of osteoarthritic cartilage
- (2011) Angus R. Upton et al. RHEUMATOLOGY INTERNATIONAL
- Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis
- (2010) Mary B. Goldring et al. Annals of the New York Academy of Sciences
- Osteochondral plate angiogenesis: A new treatment target in osteoarthritis
- (2010) Laurence Pesesse et al. JOINT BONE SPINE
- The basic science of the subchondral bone
- (2010) Henning Madry et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- (2010) Taku Saito et al. NATURE MEDICINE
- The bone–cartilage unit in osteoarthritis
- (2010) Rik J. Lories et al. Nature Reviews Rheumatology
- The discovery of Hepatocyte Growth Factor (HGF) and its significance for cell biology, life sciences and clinical medicine
- (2010) Toshikazu NAKAMURA et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis
- (2010) D. A. Walsh et al. RHEUMATOLOGY
- Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders
- (2010) Rita Dreier ARTHRITIS RESEARCH & THERAPY
- The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study
- (2010) Stephanie K Tanamas et al. ARTHRITIS RESEARCH & THERAPY
- Calcification of articular cartilage in human osteoarthritis
- (2009) M. Fuerst et al. ARTHRITIS AND RHEUMATISM
- Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene
- (2009) Akiro Higashikawa et al. ARTHRITIS AND RHEUMATISM
- Migratory Chondrogenic Progenitor Cells from Repair Tissue during the Later Stages of Human Osteoarthritis
- (2009) Sebastian Koelling et al. Cell Stem Cell
- Chondrogenesis, joint formation, and articular cartilage regeneration
- (2009) Ikemefuna Onyekwelu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- In situ measurement of transport between subchondral bone and articular cartilage
- (2009) Jun Pan et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Histomorphometric analysis of adult articular calcified cartilage zone
- (2009) Fuyou Wang et al. JOURNAL OF STRUCTURAL BIOLOGY
- Modulating hedgehog signaling can attenuate the severity of osteoarthritis
- (2009) Alvin C Lin et al. NATURE MEDICINE
- MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation
- (2009) B.-C. Sondergaard et al. OSTEOARTHRITIS AND CARTILAGE
- Osteochondral angiogenesis and increased protease inhibitor expression in OA
- (2009) R.E. Fransès et al. OSTEOARTHRITIS AND CARTILAGE
- Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis
- (2008) Jennifer Hwang et al. ARTHRITIS AND RHEUMATISM
- Zonal gene expression of chondrocytes in osteoarthritic cartilage
- (2008) Naoshi Fukui et al. ARTHRITIS AND RHEUMATISM
- A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models
- (2008) Yvonne H Sniekers et al. BMC MUSCULOSKELETAL DISORDERS
- Role of Bone in Osteoarthritis Pathogenesis
- (2008) Steven R. Goldring MEDICAL CLINICS OF NORTH AMERICA
- Solute transport in the deep and calcified zones of articular cartilage
- (2007) K.P. Arkill et al. OSTEOARTHRITIS AND CARTILAGE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More