Osteoblast-Chondrocyte Interactions in Osteoarthritis

Shock absorbing ability of articular cartilage and subchondral bone under impact compression

(2013) Fatemeh Malekipour et al.   Journal of the Mechanical Behavior of Biomedical Materials

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis

(2013) L. Pesesse et al.   OSTEOARTHRITIS AND CARTILAGE

The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis

(2013) Maricela Maldonado et al.   Biomed Research International

Homeostatic Mechanisms in Articular Cartilage and Role of Inflammation in Osteoarthritis

(2013) Xavier Houard et al.   Current Rheumatology Reports

Difference in subchondral cancellous bone between postmenopausal women with hip osteoarthritis and osteoporotic fracture: Implication for fatigue microdamage, bone microarchitecture, and biomechanical properties

(2012) Zhan-Chun Li et al.   ARTHRITIS AND RHEUMATISM

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice

(2012) Hwanhee Oh et al.   ARTHRITIS AND RHEUMATISM

In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis

(2012) Gladys Valverde-Franco et al.   ARTHRITIS AND RHEUMATISM

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

(2012) Annika Burleigh et al.   ARTHRITIS AND RHEUMATISM

Osteocyte control of osteoclastogenesis

(2012) Charles A. O'Brien et al.   BONE

Quantifying load-induced solute transport and solute-matrix interaction within the osteocyte lacunar-canalicular system

(2012) Bin Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone remodelling in osteoarthritis

(2012) David B. Burr et al.   Nature Reviews Rheumatology

Evidence for the dysregulated expression of TWIST1, TGFβ1 and SMAD3 in differentiating osteoblasts from primary hip osteoarthritis patients

(2012) D.D. Kumarasinghe et al.   OSTEOARTHRITIS AND CARTILAGE

Osteocyte regulation of bone mineral: a little give and take

(2012) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Targeting Bone Alleviates Osteoarthritis in Osteopenic Mice and Modulates Cartilage Catabolism

(2012) Thomas Funck-Brentano et al.   PLoS One

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: An in vivo microfocal computed tomography study

(2011) Sander M. Botter et al.   ARTHRITIS AND RHEUMATISM

Reduced tissue hardness of trabecular bone is associated with severe osteoarthritis

(2011) Enrico Dall'Ara et al.   JOURNAL OF BIOMECHANICS

Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts

(2011) Thomas F. Chan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Specific inhibitory protein Dkk-1 blocking Wnt/β-catenin signaling pathway improve protectives effect on the extracellular matrix

(2011) Shunan Ye et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

(2011) B.Y. Chan et al.   OSTEOARTHRITIS AND CARTILAGE

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

(2011) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

An update on primary hip osteoarthritis including altered Wnt and TGF-  associated gene expression from the bony component of the disease

(2011) D. D. Kumarasinghe et al.   RHEUMATOLOGY

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults

(2011) Dawn Dore et al.   ARTHRITIS RESEARCH & THERAPY

Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

(2011) Geetha Mohan et al.   ARTHRITIS RESEARCH & THERAPY

Strontium ranelate effect in postmenopausal women with different clinical levels of osteoarthritis

(2010) P. Alexandersen et al.   CLIMACTERIC

Bone marrow lesions in the knee: the clinical conundrum

(2010) Hassan M. BASSIOUNI   International Journal of Rheumatic Diseases

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis

(2010) D.D. Kumarasinghe et al.   OSTEOARTHRITIS AND CARTILAGE

The bone marrow lesion in osteoarthritis

(2010) Massoud Daheshia et al.   RHEUMATOLOGY INTERNATIONAL

The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

(2010) Stephanie K Tanamas et al.   ARTHRITIS RESEARCH & THERAPY

Cartilage loss occurs in the same subregions as subchondral bone attrition: A within-knee subregion-matched approach from the multicenter osteoarthritis study

(2009) T. Neogi et al.   ARTHRITIS AND RHEUMATISM

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

(2009) Denis Couchourel et al.   ARTHRITIS AND RHEUMATISM

Hypoxia and HIF-1α expression in the epiphyseal cartilage following ischemic injury to the immature femoral head

(2009) Harry K.W. Kim et al.   BONE

Chondrocyte survival in articular cartilage

(2009) A. K. Amin et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

In situ measurement of transport between subchondral bone and articular cartilage

(2009) Jun Pan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

On the role of diffusible binding partners in modulating the transport and concentration of proteins in tissues

(2009) Lihai Zhang et al.   JOURNAL OF THEORETICAL BIOLOGY

Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized

(2009) David J Hunter et al.   ARTHRITIS RESEARCH & THERAPY

Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis

(2008) A. Kadri et al.   ARTHRITIS AND RHEUMATISM

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis

(2008) Francesco Dell'Accio et al.   ARTHRITIS AND RHEUMATISM

Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology

(2008) Mihra S. Taljanovic et al.   SKELETAL RADIOLOGY