Inhibition of vascular endothelial growth factor with shRNA in chondrocytes ameliorates osteoarthritis

Injecting vascular endothelial growth factor into the temporomandibular joint induces osteoarthritis in mice

(2015) Pei Shen et al.   Scientific Reports

Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

(2014) Yun-peng Zhao et al.   ANNALS OF THE RHEUMATIC DISEASES

Animal data show VEGF blocker inhibits post-traumatic OA

(2014) Caroline Barranco   Nature Reviews Rheumatology

Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis

(2014) Toshihiro Nagai et al.   ARTHRITIS RESEARCH & THERAPY

ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis

(2013) Yongjie Lai et al.   ANNALS OF THE RHEUMATIC DISEASES

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

(2012) Yanqiu Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment

(2012) Indira Prasadam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Non-destructive evaluation of articular cartilage defects using near-infrared (NIR) spectroscopy in osteoarthritic rat models and its direct relation to Mankin score

(2012) I. Afara et al.   OSTEOARTHRITIS AND CARTILAGE

Injection of vascular endothelial growth factor into knee joints induces osteoarthritis in mice

(2012) A. Ludin et al.   OSTEOARTHRITIS AND CARTILAGE

Osteochondral alterations in osteoarthritis

(2011) Sunita Suri et al.   BONE

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

(2011) Makoto Hirata et al.   HUMAN MOLECULAR GENETICS

Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer

(2011) Feifei Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of cervical cancer cell growth in vitro and in vivo with dual shRNAs

(2010) W Gu et al.   CANCER GENE THERAPY

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis

(2010) D. A. Walsh et al.   RHEUMATOLOGY

Blocking vascular endothelial growth factor with soluble Flt-1 improves the chondrogenic potential of mouse skeletal muscle-derived stem cells

(2009) Seiji Kubo et al.   ARTHRITIS AND RHEUMATISM

Identification and Functional Characterization of ERK/MAPK Phosphorylation Sites in the Runx2 Transcription Factor

(2009) Chunxi Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development

(2008) Chisa Shukunami et al.   CELL AND TISSUE RESEARCH

The potential role of vascular endothelial growth factor (VEGF) in cartilage

(2007) M. Murata et al.   OSTEOARTHRITIS AND CARTILAGE