Layer-By-Layer Fabrication of Large and Thick Human Cardiac Muscle Patch Constructs With Superior Electrophysiological Properties

Fabrication and characterization of a thick, viable bi-layered stem cell-derived surrogate for future myocardial tissue regeneration

(2020) Danielle Pretorius et al.   Biomedical Materials

Change the Laminin, Change the Cardiomyocyte: Improve Untreatable Heart Failure

(2020) Camila Hochman-Mendez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High-dimensional cell-level analysis of tissues with Ce3D multiplex volume imaging

(2019) Weizhe Li et al.   Nature Protocols

Maturation of three-dimensional, hiPSC-derived cardiomyocyte spheroids utilizing cyclic, uniaxial stretch and electrical stimulation

(2019) Wesley LaBarge et al.   PLoS One

FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

(2019) Ekaterina Savchenko et al.   Scientific Reports

Engineered cardiac tissue patch maintains structural and electrical properties after epicardial implantation

(2018) Christopher P. Jackman et al.   BIOMATERIALS

Advanced maturation of human cardiac tissue grown from pluripotent stem cells

(2018) Kacey Ronaldson-Bouchard et al.   NATURE

The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways

(2018) Liping Su et al.   Stem Cell Research & Therapy

Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

(2017) Ilya Y. Shadrin et al.   Nature Communications

Large Cardiac Muscle Patches Engineered From Human Induced-Pluripotent Stem Cell–Derived Cardiac Cells Improve Recovery From Myocardial Infarction in Swine

(2017) Ling Gao et al.   CIRCULATION

The electrophysiological development of cardiomyocytes

(2016) Jie Liu et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac TissueClinical Perspective

(2016) Jia-Ling Ruan et al.   CIRCULATION

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors

(2015) Jia-Ling Ruan et al.   STEM CELLS

Functional Effects of a Tissue-Engineered Cardiac Patch From Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Rat Infarct Model

(2015) Jacqueline S. Wendel et al.   Stem Cells Translational Medicine

The influence of a spatiotemporal 3D environment on endothelial cell differentiation of human induced pluripotent stem cells

(2014) Sophia Zhang et al.   BIOMATERIALS

The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

(2014) Anton Mihic et al.   BIOMATERIALS

Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

(2014) Lei Ye et al.   Cell Stem Cell

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA, and EAPCI task force

(2014) Bulent Gorenek et al.   EUROPACE

Chemically defined generation of human cardiomyocytes

(2014) Paul W Burridge et al.   NATURE METHODS

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling

(2014) Xiaojun Lian et al.   Stem Cell Reports

Simultaneous Voltage and Calcium Mapping of Genetically Purified Human Induced Pluripotent Stem Cell–Derived Cardiac Myocyte Monolayers

(2012) Peter Lee et al.   CIRCULATION RESEARCH

Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes

(2012) Christine L. Mummery et al.   CIRCULATION RESEARCH

Matrix production and remodeling capacity of cardiomyocyte progenitor cells during in vitro differentiation

(2012) Noortje A.M. Bax et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo

(2011) Santanu Chakraborty et al.   DEVELOPMENTAL BIOLOGY

Ionic mechanism of shock-induced arrhythmias: Role of intracellular calcium

(2011) Brittany Sowell et al.   HEART RHYTHM

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation

(2011) Thomas O'Hara et al.   PLoS Computational Biology

Differential gene expressions in atrial and ventricular myocytes: insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies

(2010) Sze Ying Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

(2009) Masaki Ieda et al.   DEVELOPMENTAL CELL

Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells

(2008) Alanna Kennedy et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS