Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

Wnt/ -catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

(2012) K. C. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

Small-Molecule Inhibitors of the Wnt Pathway Potently Promote Cardiomyocytes From Human Embryonic Stem Cell–Derived Mesoderm

(2011) Erik Willems et al.   CIRCULATION RESEARCH

Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells

(2011) Yongming Ren et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

De novo cardiomyocytes from within the activated adult heart after injury

(2011) Nicola Smart et al.   NATURE

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells

(2011) Nicole C Dubois et al.   NATURE BIOTECHNOLOGY

NKX2-5 eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

(2011) David A Elliott et al.   NATURE METHODS

Cardiac Induction of Embryonic Stem Cells by a Small Molecule Inhibitor of Wnt/β-Catenin Signaling

(2010) Hanmin Wang et al.   ACS Chemical Biology

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

(2010) Qiangzhe Zhang et al.   CELL RESEARCH

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells

(2010) Sharon L. Paige et al.   PLoS One

In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

(2009) Jijun Hao et al.   ACS Chemical Biology

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

(2009) Justin K. Ichida et al.   Cell Stem Cell

Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells

(2009) Malgorzata Borowiak et al.   Cell Stem Cell

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

(2009) Lei Bu et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

A chemical platform for improved induction of human iPSCs

(2009) Tongxiang Lin et al.   NATURE METHODS

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Wnt3a-Induced Mesoderm Formation and Cardiomyogenesis in Human Embryonic Stem Cells

(2009) Thanh H. Tran et al.   STEM CELLS

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium

(2008) Mio Nakanishi et al.   FASEB JOURNAL

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK

(2007) Ralph Graichen et al.   DIFFERENTIATION