TRIM26 Induces Ferroptosis to Inhibit Hepatic Stellate Cell Activation and Mitigate Liver Fibrosis Through Mediating SLC7A11 Ubiquitination

Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis—A Novel Form of Non-Apoptotic Cell Death?

(2020) Ricardo U. Macías-Rodríguez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC‑27

(2020) Yingwei Sun et al.   Molecular Medicine Reports

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy

(2020) Yuechen Zhao et al.   OncoTargets and Therapy

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

(2020) Pranavi Koppula et al.   Protein & Cell

The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice

(2020) Ashraf Yusuf Rangrez et al.   Communications Biology

The deubiquitylase OTUB1 mediates ferroptosis via stabilization of SLC7A11

(2019) Tong Liu et al.   CANCER RESEARCH

Iron-Induced Liver Injury: A Critical Reappraisal

(2019) Steven A. Bloomer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

(2019) Liyuan Wang et al.   CELL DEATH AND DIFFERENTIATION

The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma

(2019) Xi Huang et al.   INTERNATIONAL JOURNAL OF CANCER

Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition

(2018) Yu Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TRIM Proteins and Their Roles in Antiviral Host Defenses

(2018) Michiel van Gent et al.   Annual Review of Virology

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Liver and blood cytokine microenvironment in HCV patients is associated to liver fibrosis score: a proinflammatory cytokine ensemble orchestrated by TNF and tuned by IL-10

(2016) Soriane de Souza-Cruz et al.   BMC MICROBIOLOGY

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Liver Fibrosis: From Pathogenesis to Novel Therapies

(2016) Ralf Weiskirchen et al.   DIGESTIVE DISEASES

Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis

(2016) Shu Dong et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets

(2016) Chong-Yang Zhang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

TRIM26 functions as a novel tumor suppressor of hepatocellular carcinoma and its downregulation contributes to worse prognosis

(2015) Yi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of liver fibrosis resolution

(2015) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

The carbon tetrachloride model in mice

(2015) D Scholten et al.   LABORATORY ANIMALS

Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response

(2015) Yong Ran et al.   Journal of Molecular Cell Biology

Liver fibrosis: Common mechanisms and antifibrotic therapies

(2015) Detlef Schuppan   Clinics and Research in Hepatology and Gastroenterology

TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

(2015) Peng Wang et al.   PLoS Pathogens

Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging

(2015) Dan Li et al.   EJNMMI Research

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

(2013) Kengo Tomita et al.   HEPATOLOGY

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

A role for autophagy during hepatic stellate cell activation

(2011) Lien F.R. Thoen et al.   JOURNAL OF HEPATOLOGY

Proline and hydroxyproline metabolism: implications for animal and human nutrition

(2010) Guoyao Wu et al.   AMINO ACIDS

Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

(2010) Tsutomu Fujii et al.   BMC GASTROENTEROLOGY