Iron-Induced Liver Injury: A Critical Reappraisal

Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-β Signaling in Murine Hepatic Stellate Cells

(2018) Kosha J. Mehta et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Erythropoietic regulators of iron metabolism

(2018) Tomas Ganz   FREE RADICAL BIOLOGY AND MEDICINE

Hepatocellular Carcinoma in β-Thalassemia Patients: Review of the Literature with Molecular Insight into Liver Carcinogenesis

(2018) Antoine Finianos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Systematic review and meta-analysis to determine the impact of iron depletion in dysmetabolic iron overload syndrome and non-alcoholic fatty liver disease

(2017) Arvind R. Murali et al.   HEPATOLOGY RESEARCH

The elemental role of iron in DNA synthesis and repair

(2017) Sergi Puig et al.   Metallomics

Reabsorption of iron into acutely damaged rat liver: A role for ferritins

(2017) Ihtzaz Ahmed Malik et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis

(2017) Tiago L. Duarte et al.   Redox Biology

Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis

(2016) Steven A. Bloomer et al.   CELL BIOCHEMISTRY AND FUNCTION

Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib

(2016) Naoki Yamamoto et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv−/− mice

(2015) Ranjit Singh Padda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Antifibrotic mechanism of deferoxamine in concanavalin A induced-liver fibrosis: Impact on interferon therapy

(2015) Samar F. Darwish et al.   BIOCHEMICAL PHARMACOLOGY

Tumour promotion versus tumour suppression in chronic hepatic iron overload

(2015) Steven A. Bloomer et al.   CELL BIOCHEMISTRY AND FUNCTION

Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload

(2015) Subhash K. Das et al.   LIVER INTERNATIONAL

Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload

(2014) Mariia Lunova et al.   JOURNAL OF HEPATOLOGY

Quantifying intracellular hydrogen peroxide perturbations in terms of concentration

(2014) Beijing K. Huang et al.   Redox Biology

Hepatic Iron Overload and Hepatocellular Carcinoma

(2014) Michael C. Kew   Liver Cancer

Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

(2013) Terrence C H Tan et al.   LABORATORY INVESTIGATION

Hepcidin and iron homeostasis

(2012) Tomas Ganz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice

(2012) Roheeth D. Delima et al.   HEPATOLOGY

Ferroportin-1 is a ‘nuclear’-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins

(2012) Naila Naz et al.   LABORATORY INVESTIGATION

Elevated Hepatic Iron Activates NF-E2–Related Factor 2–Regulated Pathway in a Dietary Iron Overload Mouse Model

(2012) Mi Sun Moon et al.   TOXICOLOGICAL SCIENCES

Improvement in Liver Pathology of Patients With β-Thalassemia Treated With Deferasirox for at Least 3 Years

(2011) Yves Deugnier et al.   GASTROENTEROLOGY

3,5,5-Trimethyl-Hexanoyl-Ferrocene Diet Protects Mice from Moderate Transient Acetaminophen-Induced Hepatotoxicity

(2011) Mi Sun Moon et al.   TOXICOLOGICAL SCIENCES

HFECys282Tyr homozygotes with serum ferritin concentrations below 1000 μg/L are at low risk of hemochromatosis

(2010) Katrina J. Allen et al.   HEPATOLOGY

Iron Potentiates Acetaminophen-Induced Oxidative Stress and Mitochondrial Dysfunction in Cultured Mouse Hepatocytes

(2010) Mi Sun Moon et al.   TOXICOLOGICAL SCIENCES

Serum hepcidin levels are related to the severity of liver histological lesions in chronic hepatitis C

(2009) E. Tsochatzis et al.   JOURNAL OF VIRAL HEPATITIS

Phagocytosis of gadolinium chloride or zymosan induces simultaneous upregulation of hepcidin- and downregulation of hemojuvelin- and Fpn-1-gene expression in murine liver

(2009) Federico Moriconi et al.   LABORATORY INVESTIGATION

Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury

(2008) Steven A. Bloomer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis

(2008) M. J. Wood et al.   BLOOD

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

(2008) Akira Uchiyama et al.   HEPATOLOGY

Iron-Overload–Related Disease inHFEHereditary Hemochromatosis

(2008) Katrina J. Allen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Attenuation of acute and chronic liver injury in rats by iron-deficient diet

(2007) Kohji Otogawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY