Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

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Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy

(2019) Debarati Banik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

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Lysosomes as a therapeutic target

(2019) Srinivasa Reddy Bonam et al.   NATURE REVIEWS DRUG DISCOVERY

Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors

(2019) Pierre Autin et al.   Cancers

Zinc dependent Histone deacetylase inhibitors in cancer therapeutics: Recent update

(2018) Faria Sultana et al.   CURRENT MEDICINAL CHEMISTRY

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

(2018) Johannes Ridinger et al.   Scientific Reports

mTORC1 as the main gateway to autophagy

(2017) Yoana Rabanal-Ruiz et al.   Essays in Biochemistry

Overview and recent advances in the treatment of neuroblastoma

(2017) Sarah B. Whittle et al.   Expert Review of Anticancer Therapy

Histone Deacetylase Inhibitors as Anticancer Drugs

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Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts

(2017) Rita Fior et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy is associated with chemoresistance in neuroblastoma

(2016) Assila Belounis et al.   BMC CANCER

HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC- Driven Medulloblastoma

(2016) Yanxin Pei et al.   CANCER CELL

Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway

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Transcriptional regulation of mammalian autophagy at a glance

(2016) Jens Füllgrabe et al.   JOURNAL OF CELL SCIENCE

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways

(2015) Jianbin Zhang et al.   Autophagy

Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations

(2015) Kristopher R. Bosse et al.   CANCER

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Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

(2014) Xiao-Hong Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia

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‘How can I halt thee?’ The puzzles involved in autophagic inhibition

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The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

(2014) J. A. Martina et al.   Science Signaling

Autophagy

(2013) Amber N. Hale et al.   Autophagy

CDK4 inhibition restores G₁-S arrest inMYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage

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Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

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Histone deacetylase 10 promotes autophagy-mediated cell survival

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Differential effect of long-term drug selection with doxorubicin and vorinostat on neuroblastoma cells with cancer stem cell characteristics

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

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FOXOphagy path to inducing stress resistance and cell survival

(2012) Marco Sandri   NATURE CELL BIOLOGY

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

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TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes

(2011) Carmine Settembre et al.   Autophagy

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

(2011) Niroop Kaza et al.   BRAIN PATHOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells

(2010) Jingyi Li et al.   Autophagy

Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

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Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century

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Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy and tumorigenesis

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HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

Autophagy in the Pathogenesis of Disease

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Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation

(2008) Motonobu Watanabe et al.   INTERNATIONAL JOURNAL OF CANCER

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The FoxO code

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