Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations
Authors
Keywords
-
Journal
CANCER
Volume 122, Issue 1, Pages 20-33
Publisher
Wiley
Online
2015-11-06
DOI
10.1002/cncr.29706
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
- (2015) M. R. Russell et al. CANCER RESEARCH
- Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
- (2015) Thomas F Eleveld et al. NATURE GENETICS
- Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma
- (2015) Lindi Chen et al. Oncotarget
- Detection of tumorALKstatus in neuroblastoma patients using peripheral blood
- (2015) Valérie Combaret et al. Cancer Medicine
- The Risk-Associated Long Noncoding RNA NBAT-1 Controls Neuroblastoma Progression by Regulating Cell Proliferation and Neuronal Differentiation
- (2014) Gaurav Kumar Pandey et al. CANCER CELL
- ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma
- (2014) Scott C. Bresler et al. CANCER CELL
- Common Genetic Variants in NEFL Influence Gene Expression and Neuroblastoma Risk
- (2014) M. Capasso et al. CANCER RESEARCH
- Intragenic anaplastic lymphoma kinase (ALK) rearrangements: Translocations as a novel mechanism ofALKactivation in neuroblastoma tumors
- (2014) Susanne Fransson et al. GENES CHROMOSOMES & CANCER
- Emergence of New ALK Mutations at Relapse of Neuroblastoma
- (2014) Gudrun Schleiermacher et al. JOURNAL OF CLINICAL ONCOLOGY
- Liquid Biopsies: Genotyping Circulating Tumor DNA
- (2014) Luis A. Diaz et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical features of ATRX or DAXX mutated neuroblastoma
- (2014) Sho Kurihara et al. JOURNAL OF PEDIATRIC SURGERY
- Rare Variants in TP53 and Susceptibility to Neuroblastoma
- (2014) Sharon J. Diskin et al. JNCI-Journal of the National Cancer Institute
- Patient-derived models of acquired resistance can identify effective drug combinations for cancer
- (2014) Adam S. Crystal et al. SCIENCE
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
- (2014) C. Bettegowda et al. Science Translational Medicine
- Weaver syndrome andEZH2mutations: Clarifying the clinical phenotype
- (2013) Katrina Tatton-Brown et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- CDK4 inhibition restores G₁-S arrest inMYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage
- (2013) Sina Gogolin et al. CELL CYCLE
- New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK
- (2013) G. Barone et al. CLINICAL CANCER RESEARCH
- Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
- (2013) J. Rader et al. CLINICAL CANCER RESEARCH
- BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma
- (2013) P. Bandopadhayay et al. CLINICAL CANCER RESEARCH
- Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study
- (2013) Yael P Mossé et al. LANCET ONCOLOGY
- The genetic landscape of high-risk neuroblastoma
- (2013) Trevor J Pugh et al. NATURE GENETICS
- Detection of MYCN amplification using blood plasma: noninvasive therapy evaluation and prediction of prognosis in neuroblastoma
- (2013) Masato Kojima et al. PEDIATRIC SURGERY INTERNATIONAL
- Breakpoint Features of Genomic Rearrangements in Neuroblastoma with Unbalanced Translocations and Chromothripsis
- (2013) Valentina Boeva et al. PLoS One
- BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models
- (2013) Anastasia Wyce et al. PLoS One
- Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma
- (2013) Jun S. Wei et al. PLoS One
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
- (2013) Alexandre Puissant et al. Cancer Discovery
- Neuroblastoma and MYCN
- (2013) M. Huang et al. Cold Spring Harbor Perspectives in Medicine
- Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project
- (2012) G Schleiermacher et al. BRITISH JOURNAL OF CANCER
- Replication of Neuroblastoma SNP Association at the BARD1 Locus in African-Americans
- (2012) V. Latorre et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- MAX and MYC: A Heritable Breakup
- (2012) A. Cascon et al. CANCER RESEARCH
- Common Variation at BARD1 Results in the Expression of an Oncogenic Isoform That Influences Neuroblastoma Susceptibility and Oncogenicity
- (2012) K. R. Bosse et al. CANCER RESEARCH
- Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma
- (2012) A. Cazes et al. CANCER RESEARCH
- Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility
- (2012) Mario Capasso et al. CARCINOGENESIS
- Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
- (2012) Nai-Kong V. Cheung JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
- (2012) Jan J. Molenaar et al. NATURE
- Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma
- (2012) Sharon J Diskin et al. NATURE GENETICS
- LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
- (2012) Jan J Molenaar et al. NATURE GENETICS
- Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma
- (2012) Mark Sausen et al. NATURE GENETICS
- Targeting ALK in neuroblastoma—preclinical and clinical advancements
- (2012) Erica L. Carpenter et al. Nature Reviews Clinical Oncology
- Two cases of localized neuroblastoma with multiple segmental chromosomal alterations and metastatic progression
- (2012) Andres Morales La Madrid et al. PEDIATRIC BLOOD & CANCER
- Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes
- (2011) Christian P. Kratz et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways
- (2011) N. Shukla et al. CLINICAL CANCER RESEARCH
- Copy number defects of G1-Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis
- (2011) Jan J. Molenaar et al. GENES CHROMOSOMES & CANCER
- Germline gain-of-function mutations of ALK disrupt central nervous system development
- (2011) Loïc de Pontual et al. HUMAN MUTATION
- Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3
- (2011) T. Van Maerken et al. MOLECULAR CANCER THERAPEUTICS
- A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
- (2011) Simon N Stacey et al. NATURE GENETICS
- MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63
- (2011) L D Gamble et al. ONCOGENE
- Determination of 17q gain in patients with neuroblastoma by analysis of circulating DNA
- (2011) Valérie Combaret et al. PEDIATRIC BLOOD & CANCER
- RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma
- (2011) K. A. Cole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered Telomeres in Tumors with ATRX and DAXX Mutations
- (2011) C. M. Heaphy et al. SCIENCE
- Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci
- (2011) Lễ B. Nguyễn et al. PLoS Genetics
- Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy
- (2010) T. Martinsson et al. CANCER RESEARCH
- NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome
- (2010) Michael Hölzel et al. CELL
- High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
- (2010) J. Carr-Wilkinson et al. CLINICAL CANCER RESEARCH
- Accumulation of Segmental Alterations Determines Progression in Neuroblastoma
- (2010) Gudrun Schleiermacher et al. JOURNAL OF CLINICAL ONCOLOGY
- Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century
- (2010) Malcolm A. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- Integrative genomics identifies LMO1 as a neuroblastoma oncogene
- (2010) Kai Wang et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma
- (2010) Alice L. Yu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Outcome after Reduced Chemotherapy for Intermediate-Risk Neuroblastoma
- (2010) David L. Baker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Recent Advances in Neuroblastoma
- (2010) John M. Maris NEW ENGLAND JOURNAL OF MEDICINE
- Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force
- (2009) K Beiske et al. BRITISH JOURNAL OF CANCER
- Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma
- (2009) Isabelle Janoueix-Lerosey et al. JOURNAL OF CLINICAL ONCOLOGY
- Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study
- (2009) Katherine K. Matthay et al. JOURNAL OF CLINICAL ONCOLOGY
- Copy number variation at 1q21.1 associated with neuroblastoma
- (2009) Sharon J. Diskin et al. NATURE
- Common variations in BARD1 influence susceptibility to high-risk neuroblastoma
- (2009) Mario Capasso et al. NATURE GENETICS
- High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors; Four cases of homozygous deletions of the CDKN2A gene
- (2008) Helena Caren et al. BMC GENOMICS
- Germline PTPN11 missense mutation in a case of Noonan syndrome associated with mediastinal and retroperitoneal neuroblastic tumors
- (2008) Léon Mutesa et al. CANCER GENETICS AND CYTOGENETICS
- Cyclin D1 and CDK4 Activity Contribute to the Undifferentiated Phenotype in Neuroblastoma
- (2008) J. J. Molenaar et al. CANCER RESEARCH
- The International Neuroblastoma Risk Group (INRG) Staging System: An INRG Task Force Report
- (2008) Tom Monclair et al. JOURNAL OF CLINICAL ONCOLOGY
- The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report
- (2008) Susan L. Cohn et al. JOURNAL OF CLINICAL ONCOLOGY
- Identification of ALK as a major familial neuroblastoma predisposition gene
- (2008) Yaël P. Mossé et al. NATURE
- Activating mutations in ALK provide a therapeutic target in neuroblastoma
- (2008) Rani E. George et al. NATURE
- Oncogenic mutations of ALK kinase in neuroblastoma
- (2008) Yuyan Chen et al. NATURE
- Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
- (2008) Isabelle Janoueix-Lerosey et al. NATURE
- Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma
- (2008) John M. Maris et al. NEW ENGLAND JOURNAL OF MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now