A Propagated Skeleton Approach to High Throughput Screening of Neurite Outgrowth for In Vitro Parkinson’s Disease Modelling

Mapping the Fine-Scale Organization and Plasticity of the Brain Vasculature

(2020) Christoph Kirst et al.   CELL

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β 1-42 pathologies

(2020) Janin Lautenschläger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat cortical neurons in culture

(2020) Martin R. Schmuck et al.   JOURNAL OF NEUROSCIENCE METHODS

Propionic Acid and Fasudil as Treatment Against Rotenone Toxicity in an In Vitro Model of Parkinson’s Disease

(2020) Friederike Ostendorf et al.   MOLECULES

Machine learning-assisted neurotoxicity prediction in human midbrain organoids

(2020) Anna S. Monzel et al.   PARKINSONISM & RELATED DISORDERS

Reversing a model of Parkinson’s disease with in situ converted nigral neurons

(2020) Hao Qian et al.   NATURE

The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration

(2019) Jared T. Hinkle et al.   MOVEMENT DISORDERS

Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone

(2019) Congcong Sun et al.   NEUROTOXICOLOGY

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons

(2019) Goutham K. Ganjam et al.   Cell Death & Disease

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

(2018) Megan F. Duffy et al.   Journal of Neuroinflammation

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Rifampicin Prevents SH-SY5Y Cells from Rotenone-Induced Apoptosis via the PI3K/Akt/GSK-3β/CREB Signaling Pathway

(2018) Xia Wu et al.   NEUROCHEMICAL RESEARCH

Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson’s Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism

(2018) Camila Mouhape et al.   NEUROTOXICITY RESEARCH

ROCK inhibition in models of neurodegeneration and its potential for clinical translation

(2018) Jan Christoph Koch et al.   PHARMACOLOGY & THERAPEUTICS

Cellular models as tools for the study of the role of alpha-synuclein in Parkinson's disease

(2017) Diana F. Lázaro et al.   EXPERIMENTAL NEUROLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro

(2016) Martin R. Schmuck et al.   ARCHIVES OF TOXICOLOGY

Cellular models for Parkinson's disease

(2016) Björn H. Falkenburger et al.   JOURNAL OF NEUROCHEMISTRY

A survey on skeletonization algorithms and their applications

(2016) Punam K. Saha et al.   PATTERN RECOGNITION LETTERS

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway

(2015) Yu-he Yuan et al.   TOXICOLOGY LETTERS

Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons

(2014) Melinda S. Wilson et al.   NEUROTOXICOLOGY

Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients

(2014) Karlijn J Doorn et al.   Acta Neuropathologica Communications

The dendritic hypothesis for Alzheimer's disease pathophysiology

(2013) J. Nicholas Cochran et al.   BRAIN RESEARCH BULLETIN

MorphoNeuroNet: An automated method for dense neurite network analysis

(2013) Giuseppe Pani et al.   CYTOMETRY PART A

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

(2012) L. Tonges et al.   BRAIN

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia

(2012) Lisa Fellner et al.   GLIA

An Image Skeletonization-Based Tool for Pollen Tube Morphology Analysis and PhenotypingF

(2012) Chaofeng Wang et al.   Journal of Integrative Plant Biology

Biological imaging software tools

(2012) Kevin W Eliceiri et al.   NATURE METHODS

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

NeurphologyJ: An automatic neuronal morphology quantification method and its application in pharmacological discovery

(2011) Shinn-Ying Ho et al.   BMC BIOINFORMATICS

Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth

(2011) Joshua A. Harrill et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial dysfunction in Parkinson's disease

(2009) Konstanze F. Winklhofer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Neuronal and Astrocyte Co-Culture Assay for High Content Analysis of Neurotoxicity

(2009) Janet L Anderl et al.   Jove-Journal of Visualized Experiments

Developmental neurotoxicity testing in vitro: Models for assessing chemical effects on neurite outgrowth

(2008) Nicholas M. Radio et al.   NEUROTOXICOLOGY

NeuriteTracer: A novel ImageJ plugin for automated quantification of neurite outgrowth

(2007) Madeline Pool et al.   JOURNAL OF NEUROSCIENCE METHODS