The Tissue Renin-Angiotensin System and Its Role in the Pathogenesis of Major Human Diseases: Quo Vadis?
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Title
The Tissue Renin-Angiotensin System and Its Role in the Pathogenesis of Major Human Diseases: Quo Vadis?
Authors
Keywords
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Journal
Cells
Volume 10, Issue 3, Pages 650
Publisher
MDPI AG
Online
2021-03-15
DOI
10.3390/cells10030650
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Note: Only part of the references are listed.- Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury
- (2020) Yingxia Liu et al. Science China-Life Sciences
- Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- (2020) Renato D. Lopes et al. AMERICAN HEART JOURNAL
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- Risks of ACE Inhibitor and ARB Usage in COVID‐19: Evaluating the Evidence
- (2020) Krishna Sriram et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- COVID-19 cytokine storm: The anger of inflammation
- (2020) Mehdi Mahmudpour et al. CYTOKINE
- Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors
- (2020) Iziah E Sama et al. EUROPEAN HEART JOURNAL
- Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts
- (2020) Luka Nicin et al. EUROPEAN HEART JOURNAL
- The liaison between respiratory failure and high blood pressure: evidence from COVID-19 patients
- (2020) Marco Vicenzi et al. EUROPEAN RESPIRATORY JOURNAL
- Understanding the Renin-Angiotensin-Aldosterone-SARS-CoV-Axis: A Comprehensive Review
- (2020) Nicholas E. Ingraham et al. EUROPEAN RESPIRATORY JOURNAL
- Effect of renin–angiotensin system on senescence
- (2020) Masaki Mogi Geriatrics & Gerontology International
- Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19
- (2020) Hisashi Kai et al. HYPERTENSION RESEARCH
- Recombinant human ACE2: potential therapeutics of SARS-CoV-2 infection and its complication
- (2020) Xiaocong Pang et al. ACTA PHARMACOLOGICA SINICA
- COVID-19
- (2020) Paolo Verdecchia et al. HYPERTENSION
- A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm
- (2020) Michael R Garvin et al. eLife
- Targeting the Protective Arm of the Renin-Angiotensin System to Reduce Systemic Lupus Erythematosus Related Pathologies in MRL-lpr Mice
- (2020) Maira Soto et al. Frontiers in Immunology
- Renin-Angiotensin System and Coronavirus Disease 2019: A Narrative Review
- (2020) Annamaria Mascolo et al. Frontiers in Cardiovascular Medicine
- Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19
- (2020) Marina Rieder et al. AMERICAN JOURNAL OF HYPERTENSION
- Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?
- (2020) Pawel Namsolleck et al. MOLECULAR MEDICINE
- Human recombinant soluble ACE2 in severe COVID-19
- (2020) Alexander Zoufaly et al. Lancet Respiratory Medicine
- Sacubitril/Valsartan
- (2020) Kieran F. Docherty et al. JACC-Heart Failure
- Modeling the Molecular Impact of SARS-CoV-2 Infection on the Renin-Angiotensin System
- (2020) Fabrizio Pucci et al. Viruses-Basel
- A dramatic rise in serum ACE2 activity in a critically ill COVID-19 patient
- (2020) Béla Nagy et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?
- (2019) Annamaria Mascolo et al. HEART FAILURE REVIEWS
- The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor axis as a key player in alveolar bone remodeling
- (2019) Celso Martins Queiroz-Junior et al. BONE
- Activation of the Protective Arm of the Renin Angiotensin System in Demyelinating Disease
- (2019) Roslynn E. Stone et al. Journal of Neuroimmune Pharmacology
- A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension
- (2018) Anna R. Hemnes et al. EUROPEAN RESPIRATORY JOURNAL
- Eccentric Overload Muscle Damage is Attenuated By a Novel Angiotensin- (1-7) Treatment
- (2018) Lenice Becker et al. INTERNATIONAL JOURNAL OF SPORTS MEDICINE
- Inflammatory Renin-Angiotensin System Disruption Attenuates Sensory Hyperinnervation and Mechanical Hypersensitivity in a Rat Model of Provoked Vestibulodynia
- (2018) Anuradha Chakrabarty et al. JOURNAL OF PAIN
- 2018 ESC/ESH Guidelines for the management of arterial hypertension
- (2018) Bryan Williams et al. EUROPEAN HEART JOURNAL
- Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice
- (2018) Hikari Takeshita et al. Journal of Cachexia Sarcopenia and Muscle
- Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure
- (2018) Ryousuke Satou et al. CURRENT HYPERTENSION REPORTS
- Sarcopenia: Aging-Related Loss of Muscle Mass and Function
- (2018) Lars Larsson et al. PHYSIOLOGICAL REVIEWS
- A Local Inflammatory Renin-Angiotensin System Drives Sensory Axon Sprouting in Provoked Vestibulodynia
- (2017) Zhaohui Liao et al. JOURNAL OF PAIN
- 2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure
- (2017) Clyde W. Yancy et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Local Renin Angiotensin Aldosterone Systems and Cardiovascular Diseases
- (2017) Walmor C. De Mello MEDICAL CLINICS OF NORTH AMERICA
- The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system
- (2017) Begoña Villar-Cheda et al. Cell Death & Disease
- Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis
- (2017) Hatem M. Abuohashish et al. Scientific Reports
- Ang II-AT2R increases mesenchymal stem cell migration by signaling through the FAK and RhoA/Cdc42 pathways in vitro
- (2017) Xiu-ping Xu et al. Stem Cell Research & Therapy
- Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium
- (2017) Riccardo Terenzi et al. Scientific Reports
- Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice
- (2016) Stephen R. Spindler et al. AGE
- Effect of Angiotensin II Type I Receptor Blockade with Valsartan on Carotid Artery Atherosclerosis: A Double Blind Randomized Clinical Trial Comparing Valsartan and Placebo (EFFERVESCENT)
- (2016) Ronnie Ramadan et al. AMERICAN HEART JOURNAL
- Intracrine angiotensin II functions originate from noncanonical pathways in the human heart
- (2016) Carlos M. Ferrario et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Olmesartan Prevented Intra-articular Inflammation Induced by Zymosan in Rats
- (2016) Gerlane Coelho Bernardo Guerra et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Renin-Angiotensin-Aldosterone System: A Current Drug Target for the Management of Neuropathic Pain
- (2016) Arunachalam Muthuraman et al. CURRENT DRUG TARGETS
- 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
- (2016) Piotr Ponikowski et al. EUROPEAN HEART JOURNAL
- The therapeutic potential of renin angiotensin aldosterone system (RAAS) in chronic pain: from preclinical studies to clinical trials
- (2016) Flavien Bessaguet et al. Expert Review of Neurotherapeutics
- Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice
- (2016) Hye Eun Yoon et al. Oxidative Medicine and Cellular Longevity
- Role of the receptor Mas in macrophage-mediated inflammation in vivo
- (2016) Anna Hammer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The therapeutic potential of renin angiotensin aldosterone system (RAAS) in chronic pain: from preclinical studies to clinical trials
- (2016) Flavien Bessaguet et al. Expert Review of Neurotherapeutics
- Hypertension: Renin-Angiotensin-Aldosterone System Alterations
- (2015) L. te Riet et al. CIRCULATION RESEARCH
- Angiotensin II in inflammation, immunity and rheumatoid arthritis
- (2015) Y. Chang et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
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- (2015) Uma Anand et al. Molecular Pain
- Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration
- (2015) Carmen Diaz-Ruiz et al. Oncotarget
- Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression
- (2015) Chizuru Yabumoto et al. Scientific Reports
- Effects of Olmesartan on Endothelial Progenitor Cell Mobilization and Function in Carotid Atherosclerosis
- (2015) Yong Zou MEDICAL SCIENCE MONITOR
- Angiotensin 1–7 Ameliorates Diabetic Cardiomyopathy and Diastolic Dysfunction in db/db Mice by Reducing Lipotoxicity and Inflammation
- (2014) Jun Mori et al. Circulation-Heart Failure
- Effects of Irbesartan on Inflammatory Cytokine Concentrations in Patients with Chronic Glomerulonephritis
- (2014) Shuichi Tsuruoka et al. INTERNAL MEDICINE
- Renin–angiotensin system in pain: Existing in a double life?
- (2014) Anjana Bali et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Aging-related dysregulation of dopamine and angiotensin receptor interaction
- (2014) Begoña Villar-Cheda et al. NEUROBIOLOGY OF AGING
- Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
- (2014) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- The role of renin-angiotensin system modulation on treatment and prevention of liver diseases
- (2014) Simone Moreira de Macêdo et al. PEPTIDES
- Effects of Exercise Training on Circulating and Skeletal Muscle Renin-Angiotensin System in Chronic Heart Failure Rats
- (2014) Igor Lucas Gomes-Santos et al. PLoS One
- Brain renin-angiotensin system and dopaminergic cell vulnerability
- (2014) Jose L. Labandeira-GarcÃa et al. Frontiers in Neuroanatomy
- The renin-angiotensin system and aging in the kidney
- (2014) Hye Eun Yoon et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury
- (2013) Gerry T. M. Wagenaar et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects
- (2013) Manuel Haschke et al. CLINICAL PHARMACOKINETICS
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- (2013) Tadashi Yoshida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Combination of Low-Dose Fluvastatin and Valsartan Decreases Inflammation and Oxidative Stress in Apparently Healthy Middle-Aged Males
- (2013) Miodrag Janić et al. Journal of Cardiopulmonary Rehabilitation and Prevention
- Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice
- (2013) Peng Gao et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Dopamine-Angiotensin interactions in the basal ganglia and their relevance for Parkinson's disease
- (2013) Jose L. Labandeira-Garcia et al. MOVEMENT DISORDERS
- Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efficacy in Rats
- (2013) Maree T. Smith et al. PAIN MEDICINE
- A Role for the Brain RAS in Alzheimer’s and Parkinson’s Diseases
- (2013) John W. Wright et al. Frontiers in Endocrinology
- Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity
- (2012) Ariela Benigni et al. AGE
- Impact of the AT2 Receptor Agonist C21 on Blood Pressure and Beyond
- (2012) Sébastien Foulquier et al. CURRENT HYPERTENSION REPORTS
- Angiotensin II type 2 receptor (AT2R) localization and antagonist-mediated inhibition of capsaicin responses and neurite outgrowth in human and rat sensory neurons
- (2012) U. Anand et al. EUROPEAN JOURNAL OF PAIN
- Evaluation of the effect of losartan and methotrexate combined therapy in adjuvant-induced arthritis in rats
- (2012) Rowaida Refaat et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats
- (2012) Jennifer Lo et al. EXPERIMENTAL PHYSIOLOGY
- Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice
- (2012) Vaibhav B. Patel et al. HYPERTENSION
- Enhanced Angiotensin II-Induced Cardiac and Aortic Remodeling in ACE2 Knockout Mice
- (2012) Mahmoud S. Alghamri et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Emergence and evolution of the renin–angiotensin–aldosterone system
- (2012) David Fournier et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1–7/Mas axis
- (2011) Bruce D. Uhal et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Four-year clinical outcomes of the OLIVUS-Ex (impact of Olmesartan on progression of coronary atherosclerosis: Evaluation by intravascular ultrasound) extension trial
- (2011) Atsushi Hirohata et al. ATHEROSCLEROSIS
- Angiotensin II induced catabolic effect and muscle atrophy are redox dependent
- (2011) Laura C. Semprun-Prieto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation
- (2011) Shinya Kuwashiro et al. CELL AND TISSUE RESEARCH
- Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis
- (2011) Roberto Fogari et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Angiotensin II Upregulates Protein Phosphatase 2Cα and Inhibits AMP-Activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting
- (2011) A. Michael Tabony et al. HYPERTENSION
- Effects of 1-year administration of olmesartan on portal pressure and TGF-beta1 in selected patients with cirrhosis: a randomized controlled trial
- (2011) Hisashi Hidaka et al. JOURNAL OF GASTROENTEROLOGY
- Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade
- (2011) W Michael Zawada et al. Journal of Neuroinflammation
- Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells
- (2010) Chunjie Han et al. ATHEROSCLEROSIS
- Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction
- (2010) JiuChang Zhong et al. CIRCULATION
- The Frail Renin-Angiotensin System
- (2010) Peter M. Abadir CLINICS IN GERIATRIC MEDICINE
- Angiotensin II revisited: new roles in inflammation, immunology and aging
- (2010) Ariela Benigni et al. EMBO Molecular Medicine
- Direct Angiotensin II Type 2 Receptor Stimulation Acts Anti-Inflammatory Through Epoxyeicosatrienoic Acid and Inhibition of Nuclear Factor κB
- (2010) Franziska Rompe et al. HYPERTENSION
- The Effect of Losartan and Amlodipine on Left Ventricular Diastolic Function and Atherosclerosis in Japanese Patients with Mild-to-Moderate Hypertension (J-ELAN) study
- (2010) Kazuhiro Yamamoto et al. HYPERTENSION RESEARCH
- Impact of Olmesartan on Progression of Coronary Atherosclerosis
- (2010) Atsushi Hirohata et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Developmental changes in AT1 and AT2 receptor-protein expression in rats
- (2010) Li Yu et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
- (2010) Begoña Villar-Cheda et al. NEUROBIOLOGY OF AGING
- Signaling mechanisms of angiotensin II in regulating vascular senescence
- (2009) Li-Juan Min et al. AGEING RESEARCH REVIEWS
- Long term treatment with ACE inhibitor enalapril decreases body weight gain and increases life span in rats
- (2009) Edson Lucas Santos et al. BIOCHEMICAL PHARMACOLOGY
- Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction
- (2009) Zamaneh Kassiri et al. Circulation-Heart Failure
- Disruption of the Ang II type 1 receptor promotes longevity in mice
- (2009) Ariela Benigni et al. JOURNAL OF CLINICAL INVESTIGATION
- Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue
- (2009) Hiroshi Kudo et al. LIVER INTERNATIONAL
- Angiotensin receptor blockers reduce erythrocyte sedimentation rate levels in patients with rheumatoid arthritis
- (2008) M E Perry et al. ANNALS OF THE RHEUMATIC DISEASES
- SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells
- (2008) Ryohei Miyazaki et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- ACE inhibition with perindopril and biomarkers of atherosclerosis and thrombosis: Results from the PERTINENT study
- (2008) Claudio Ceconi et al. ATHEROSCLEROSIS
- Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Arthritis
- (2008) Andreas J. Flammer et al. CIRCULATION
- Local adipose tissue renin-angiotensin system
- (2008) Lisa A. Cassis et al. CURRENT HYPERTENSION REPORTS
- Estrogen Elicits Dorsal Root Ganglion Axon Sprouting via a Renin-Angiotensin System
- (2008) Anuradha Chakrabarty et al. ENDOCRINOLOGY
- Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects
- (2008) Seiichiro Kurita et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Angiotensin II Type 2 Receptor Blockade Increases Bone Mass
- (2008) Yayoi Izu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS
- (2008) J. Rodriguez-Pallares et al. NEUROBIOLOGY OF DISEASE
- AT2 receptors: Functional relevance in cardiovascular disease
- (2008) Emma S. Jones et al. PHARMACOLOGY & THERAPEUTICS
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