The Role of Macrophages in Cancer Development and Therapy

Phase 1 Study of the CD47 Blocker TTI-621 in Patients with Relapsed or Refractory Hematologic Malignancies

(2021) Stephen M Ansell et al.   CLINICAL CANCER RESEARCH

Absence of CCR2 reduces spontaneous intestinal tumorigenesis in the Apc Min /+ mouse model

(2021) Venkatakrishna Rao Jala et al.   INTERNATIONAL JOURNAL OF CANCER

Chimeric antigen receptor T cells engineered to secrete CD40 agonist antibodies enhance antitumor efficacy

(2021) Yajun Zhang et al.   Journal of Translational Medicine

Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors

(2021) Jason J Luke et al.   Journal for ImmunoTherapy of Cancer

Phase I dose‐escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer

(2020) Takaaki Masuda et al.   CANCER SCIENCE

Long-term disease control by trabectedin in a patient with dedifferentiated liposarcoma

(2020) Shogo Matsuda et al.   MEDICINE

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

(2020) Hui Yang et al.   Molecular Cancer

The CD24+ cell subset promotes invasion and metastasis in human osteosarcoma

(2020) Zhenhua Zhou et al.   EBioMedicine

Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

(2020) Sharmilla Devi Jayasingam et al.   Frontiers in Oncology

Tumor microenvironment complexity and therapeutic implications at a glance

(2020) Roghayyeh Baghban et al.   Cell Communication and Signaling

Combined PD-1 inhibition (Pembrolizumab) and CCR5 inhibition (Maraviroc) for the treatment of refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): First results of the PICCASSO phase I trial.

(2020) Georg Martin Haag et al.   JOURNAL OF CLINICAL ONCOLOGY

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

(2020) Bruno Bockorny et al.   NATURE MEDICINE

CCL2 Expression in Tumor Cells and Tumor-Infiltrating Immune Cells Shows Divergent Prognostic Potential for Bladder Cancer Patients Depending on Lymph Node Stage

(2020) Markus Eckstein et al.   Cancers

ENLIVEN study: Pexidartinib for tenosynovial giant cell tumor (TGCT)

(2020) William Tap   Future Oncology

Role of CD47 in Hematological Malignancies

(2020) Entsar Eladl et al.   Journal of Hematology & Oncology

A decade of immune-checkpoint inhibitors in cancer therapy

(2020) Caroline Robert   Nature Communications

The CCL5/CCR5 Axis in Cancer Progression

(2020) Donatella Aldinucci et al.   Cancers

Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy

(2020) Patrícia Figueiredo et al.   Acta Biomaterialia

CtBP1 promotes tumour‐associated macrophage infiltration and progression in non–small‐cell lung cancer

(2020) Zhenxing Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Zoledronic acid inhibits thyroid cancer stemness and metastasis by repressing M2-like tumor-associated macrophages induced Wnt/β-catenin pathway

(2020) Juan Lv et al.   LIFE SCIENCES

Prognostic significance of tumor-associated macrophages: past, present and future

(2020) Nina Cortese et al.   SEMINARS IN IMMUNOLOGY

Characteristics and clinical trial results of agonistic anti‑CD40 antibodies in the treatment of malignancies (Review)

(2020) Da-Ke Li et al.   Oncology Letters

Localized Interleukin-12 for Cancer Immunotherapy

(2020) Khue G. Nguyen et al.   Frontiers in Immunology

Safety and efficacy of AMG 820, an anti-colony-stimulating factor 1 receptor antibody, in combination with pembrolizumab in adults with advanced solid tumors

(2020) Albiruni RA Razak et al.   Journal for ImmunoTherapy of Cancer

Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes

(2020) Hao Li et al.   BIOMATERIALS

Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

(2020) Linnéa La Fleur et al.   CANCER RESEARCH

Advances of CCR5 antagonists: From small molecules to macromolecules

(2020) Baowen Qi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study

(2020) Mark H O'Hara et al.   LANCET ONCOLOGY

A European, Observational, Prospective Trial of Trabectedin Plus Pegylated Liposomal Doxorubicin in Patients with Platinum‐Sensitive Ovarian Cancer

(2020) Sandro Pignata et al.   ONCOLOGIST

The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma

(2020) Payal Mittal et al.   Cancers

Trabectedin Plus Radiotherapy for Advanced Soft-Tissue Sarcoma: Experience in Forty Patients Treated at a Sarcoma Reference Center

(2020) Nadia Hindi et al.   Cancers

Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

(2020) Megan M. Tu et al.   Communications Biology

TD-92, a novel erlotinib derivative, depletes tumor-associated macrophages in non-small cell lung cancer via down-regulation of CSF-1R and enhances the anti-tumor effects of anti-PD-1

(2020) Chi-Ting Shih et al.   CANCER LETTERS

First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers

(2019) Branimir I. Sikic et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

(2019) Xiu-Tao Fu et al.   Cancer Cell International

Phase I Study of Emactuzumab Single Agent or in Combination with Paclitaxel in Patients with Advanced/Metastatic Solid Tumors Reveals Depletion of Immunosuppressive M2-like Macrophages

(2019) C A Gomez-Roca et al.   ANNALS OF ONCOLOGY

Phase 1 study of LY3022855, a colony-stimulating factor-1 receptor (CSF-1R) inhibitor, in patients with metastatic breast cancer (MBC) or metastatic castration-resistant prostate cancer (MCRPC).

(2019) Karen A. Autio et al.   JOURNAL OF CLINICAL ONCOLOGY

TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion

(2019) Naveen Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RRx-001 Acts as a Dual Small Molecule Checkpoint Inhibitor by Downregulating CD47 on Cancer Cells and SIRP-α on Monocytes/Macrophages

(2019) Pedro Cabrales   Translational Oncology

Macrophages‐Triggered Sequential Remodeling of Endothelium‐Interstitial Matrix to Form Pre‐Metastatic Niche in Microfluidic Tumor Microenvironment

(2019) Hyunho Kim et al.   Advanced Science

Interaction of tumor-associated macrophages and cancer chemotherapy

(2019) Irina Larionova et al.   OncoImmunology

Recent Advances targeting CCR5 for Cancer and its Role in Immuno-Oncology

(2019) Xuanmao Jiao et al.   CANCER RESEARCH

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma

(2019) Marcus Noel et al.   INVESTIGATIONAL NEW DRUGS

Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications

(2019) Yuxin Lin et al.   Journal of Hematology & Oncology

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy

(2019) Amira A. Barkal et al.   NATURE

Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer

(2019) Lisha Zhou et al.   ONCOGENE

Tumor‑infiltrating M2�macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer

(2019) Yongping Xue et al.   ONCOLOGY REPORTS

Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma

(2019) Malgorzata Czystowska-Kuzmicz et al.   Nature Communications

Crosstalk between cancer and immune cells: Role of tumor-associated macrophages in the tumor microenvironment

(2019) Jing Wang et al.   Cancer Medicine

IL-1 Family Members in Cancer; Two Sides to Every Story

(2019) Kevin J. Baker et al.   Frontiers in Immunology

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Prognostic Significance of Tumor-Associated Macrophage Content in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis

(2019) Ayan Tyagi Kumar et al.   Frontiers in Oncology

CD40 Agonist Antibodies in Cancer Immunotherapy

(2019) Robert H. Vonderheide   Annual Review of Medicine

Propagermanium Induces NK Cell Maturation and Tends to Prolong Overall Survival of Patients With Refractory Cancer

(2019) SHOJIRO KIKUCHI et al.   ANTICANCER RESEARCH

REPLATINUM Phase III randomized study: RRx-001 + platinum doublet versus platinum doublet in third-line small cell lung cancer

(2019) Bryan Oronsky et al.   Future Oncology

CAR T cell therapy: A new era for cancer treatment (Review)

(2019) Rimjhim Mohanty et al.   ONCOLOGY REPORTS

CD47 Expression Defines Efficacy of Rituximab with CHOP in Non–Germinal Center B-cell (Non-GCB) Diffuse Large B-cell Lymphoma Patients (DLBCL), but Not in GCB DLBCL

(2019) Renée Bouwstra et al.   Cancer Immunology Research

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

(2019) WeiYu Lin et al.   Frontiers in Immunology

Tumor angiogenesis: causes, consequences, challenges and opportunities

(2019) Roberta Lugano et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pexidartinib: First Approval

(2019) Yvette N. Lamb   DRUGS

The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

(2019) Katherine A. Michaelis et al.   Nature Communications

Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers

(2019) F. Zhang et al.   Nature Communications

CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas

(2019) Joseph A. Flores-Toro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Strategies to Target Tumor-Associated-Macrophages to Improve Anti-Tumor Immune Responses

(2019) Anfray et al.   Cells

Role of Matrix Metalloproteinases in Angiogenesis and Cancer

(2019) Saray Quintero-Fabián et al.   Frontiers in Oncology

Immune suppression and reversal of the suppressive tumor microenvironment

(2018) Kanako Shimizu et al.   INTERNATIONAL IMMUNOLOGY

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

(2018) Linnéa La Fleur et al.   INTERNATIONAL JOURNAL OF CANCER

Overall survival in a trial of orally administered CCR2 inhibitor CCX872 in locally advanced/metastatic pancreatic cancer: Correlation with blood monocyte counts.

(2018) David Linehan et al.   JOURNAL OF CLINICAL ONCOLOGY

Role of the NFκB-signaling pathway in cancer

(2018) Longzheng Xia et al.   OncoTargets and Therapy

Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment

(2018) Zofia Pilch et al.   Cancer Immunology Research

TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression

(2018) Aurobind Vidyarthi et al.   Frontiers in Immunology

Targeting Macrophages in Cancer: From Bench to Bedside

(2018) Ashleigh R. Poh et al.   Frontiers in Oncology

Paclitaxel reduces tumor growth by reprogramming tumor-associated macrophages to an M1- profile in a TLR4-dependent manner

(2018) Carlos W Wanderley et al.   CANCER RESEARCH

Initial results from first-in-human study of IPI-549, a tumor macrophage-targeting agent, combined with nivolumab in advanced solid tumors.

(2018) Ryan J. Sullivan et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth

(2018) Victor LJL Thijssen et al.   JOURNAL OF PATHOLOGY

Overview of CD24 as a new molecular marker in ovarian cancer

(2018) Vahideh Tarhriz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Modulation of the CCR6-CCL20 Axis: A Potential Therapeutic Target in Inflammation and Cancer

(2018) Ranmali Ranasinghe et al.   Medicina-Lithuania

Molecular Repolarisation of Tumour-Associated Macrophages

(2018) Floris van Dalen et al.   MOLECULES

Targeting Macrophage-Recruiting Chemokines as a Novel Therapeutic Strategy to Prevent the Progression of Solid Tumors

(2018) David Argyle et al.   Frontiers in Immunology

Macrophages as Key Drivers of Cancer Progression and Metastasis

(2017) Sebastian R. Nielsen et al.   MEDIATORS OF INFLAMMATION

EMT and inflammation: inseparable actors of cancer progression

(2017) Meggy Suarez-Carmona et al.   Molecular Oncology

Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas

(2017) D Yan et al.   ONCOGENE

Prognostic role of tumour-associated macrophages and macrophage scavenger receptor 1 in prostate cancer: a systematic review and meta-analysis

(2017) Jian Cao et al.   Oncotarget

Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy

(2017) Xiang Zheng et al.   Oncotarget

Toll-Like Receptor Ligands and Interferon-γ Synergize for Induction of Antitumor M1 Macrophages

(2017) Elisabeth Müller et al.   Frontiers in Immunology

Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity

(2017) Xenia Geeraerts et al.   Frontiers in Immunology

Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

(2017) Michael A. Cannarile et al.   Journal for ImmunoTherapy of Cancer

RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials

(2016) Bryan Oronsky et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Efficacy of trabectedin for the treatment of liposarcoma

(2016) Ritika Zijoo et al.   EXPERT OPINION ON PHARMACOTHERAPY

PI3Kγ is a molecular switch that controls immune suppression

(2016) Megan M. Kaneda et al.   NATURE

Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment

(2016) Manuela Liguori et al.   Oncotarget

Targeting the CCL2-CCR2 signaling axis in cancer metastasis

(2016) Su Yin Lim et al.   Oncotarget

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

CCL2 as a potential therapeutic target for clear cell renal cell carcinoma

(2016) Ryuichiro Arakaki et al.   Cancer Medicine

Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma

(2015) A. H. Rook et al.   BLOOD

The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours

(2015) S J Thomas et al.   BRITISH JOURNAL OF CANCER

Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma

(2015) Xiaoguang Li et al.   GUT

A novel antibody targeting CD24 and hepatocellular carcinoma in vivo by near-infrared fluorescence imaging

(2015) Hua He et al.   IMMUNOBIOLOGY

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses

(2015) Christina E. Arnold et al.   IMMUNOBIOLOGY

F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner

(2015) Kanae Yumimoto et al.   JOURNAL OF CLINICAL INVESTIGATION

The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages

(2015) Sarah T. Boyle et al.   Molecular Cancer

Downregulation of CCR5 inhibits the proliferation and invasion of cervical cancer cells and is regulated by microRNA-107

(2015) LI-FAN CHE et al.   Experimental and Therapeutic Medicine

Combined Effects of Pericytes in the Tumor Microenvironment

(2015) Aline Lopes Ribeiro et al.   Stem Cells International

Clinical significance of PD-L1 protein expression on tumor-associated macrophages in lung cancer

(2015) Kurt Schalper et al.   Journal for ImmunoTherapy of Cancer

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype

(2015) Katia Beider et al.   Oncotarget

Trabectedin, a drug acting on both cancer cells and the tumour microenvironment

(2014) M D’Incalci et al.   BRITISH JOURNAL OF CANCER

CCL20 and CXCL8 synergize to promote progression and poor survival outcome in patients with colorectal cancer by collaborative induction of the epithelial–mesenchymal transition

(2014) Xian-Shuo Cheng et al.   CANCER LETTERS

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

(2014) Muhammad Zaeem Noman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study

(2014) Irene Brana et al.   Targeted Oncology

Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis

(2014) Vladimir Riabov et al.   Frontiers in Physiology

Chronic Inflammation and Cytokines in the Tumor Microenvironment

(2014) Glauben Landskron et al.   Journal of Immunology Research

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

(2013) Giovanni Germano et al.   CANCER CELL

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

(2013) Rebecca S. Cook et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF- : Guardian of T Cell Function

(2013) S. A. Oh et al.   JOURNAL OF IMMUNOLOGY

At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy

(2013) Andrew M. Intlekofer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

High-Infiltration of Tumor-Associated Macrophages Predicts Unfavorable Clinical Outcome for Node-Negative Breast Cancer

(2013) Yue Zhang et al.   PLoS One

Trabectedin

(2013) Paola Allavena et al.   OncoImmunology

Phase I/II study of Resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with melanoma

(2013) Rachel L Sabado et al.   Journal for ImmunoTherapy of Cancer

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

(2012) Anne-Katrine Bonde et al.   BMC CANCER

T-cell-independent Antitumor Effects of CD40 Ligation

(2012) Alexander L. Rakhmilevich et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Overexpression of CCL20 and its receptor CCR6 predicts poor clinical prognosis in human gliomas

(2012) Liang Wang et al.   MEDICAL ONCOLOGY

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

(2011) Philippe A Cassier et al.   BMC CANCER

Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs

(2011) Qing Chen et al.   CANCER CELL

Effective antibody therapy induces host-protective antitumor immunity that is augmented by TLR4 agonist treatment

(2011) Shangzi Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Involvement of CCR6/CCL20/IL-17 Axis in NSCLC Disease Progression

(2011) Sophie Kirshberg et al.   PLoS One

Anibamine, a natural product CCR5 antagonist, as a novel lead for the development of anti-prostate cancer agents

(2010) Xueping Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma

(2010) J D Veltman et al.   BRITISH JOURNAL OF CANCER

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

(2009) H. J. Kim et al.   GENOME RESEARCH

Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

(2009) Dorothée Duluc et al.   INTERNATIONAL JOURNAL OF CANCER

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

(2009) Binzhi Qian et al.   PLoS One

How do Regulatory T Cells Work?

(2009) A. Corthay   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells

(2008) Selina Khan et al.   MOLECULAR IMMUNOLOGY

Synergy between Coproduced CC and CXC Chemokines in Monocyte Chemotaxis through Receptor-Mediated Events

(2008) M. Gouwy et al.   MOLECULAR PHARMACOLOGY

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE