Crosstalk between cancer and immune cells: Role of tumor-associated macrophages in the tumor microenvironment

Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy

(2019) Jun Wang et al.   NATURE MEDICINE

Prostaglandin E2 Inhibits Prostate Cancer Progression by Countervailing Tumor Microenvironment-Induced Impairment of Dendritic Cell Migration through LXRα/CCR7 Pathway

(2018) Kuang Youlin et al.   Journal of Immunology Research

Inhibitory functions of PD-L1 and PD-L2 in the regulation of anti-tumor immunity in murine tumor microenvironment

(2018) Daisuke Umezu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Pro-inflammatory M1 macrophage enhances metastatic potential of ovarian cancer cells through NF-κB activation

(2017) Untack Cho et al.   MOLECULAR CARCINOGENESIS

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

(2017) Janet Lau et al.   Nature Communications

An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma

(2016) Hasita Horlad et al.   CANCER SCIENCE

Endothelial progenitor cells promote tumor growth and progression by enhancing new vessel formation

(2016) Xin Zhao et al.   Oncology Letters

Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling

(2016) Gab-Yong Bae et al.   Oncotarget

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma

(2016) Marilène Binsfeld et al.   Oncotarget

Innate Immune Recognition of Cancer

(2015) Seng-Ryong Woo et al.   Annual Review of Immunology

Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators

(2015) Daniela P. Vasconcelos et al.   BIOMATERIALS

Chronic inflammation and cancer: emerging roles of triggering receptors expressed on myeloid cells

(2015) Austin Huy Nguyen et al.   Expert Review of Clinical Immunology

Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature

(2015) Elena I. Deryugina et al.   MATRIX BIOLOGY

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Molecular and epigenetic basis of macrophage polarized activation

(2015) Chiara Porta et al.   SEMINARS IN IMMUNOLOGY

The role of macrophage phenotype in vascularization of tissue engineering scaffolds

(2014) Kara L. Spiller et al.   BIOMATERIALS

Targeting IL-10 in Auto-immune Diseases

(2014) Guo Tian et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

IL-6 and related cytokines as the critical lynchpins between inflammation and cancer

(2014) Koji Taniguchi et al.   SEMINARS IN IMMUNOLOGY

Transforming growth factor-beta and its implication in the malignancy of gliomas

(2014) Laurent-Olivier Roy et al.   Targeted Oncology

SOCS Proteins in Macrophage Polarization and Function

(2014) Heather M. Wilson   Frontiers in Immunology

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells

(2013) Esther Bertran et al.   HEPATOLOGY

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers

(2013) Seok-Rae Park   Immune Network

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Macrophages in Tumor Microenvironments and the Progression of Tumors

(2012) Ning-Bo Hao et al.   Clinical & Developmental Immunology

Mast cells and inflammation

(2012) Laurent Frenzel et al.   JOINT BONE SPINE

Zyxin Is a Transforming Growth Factor-β (TGF-β)/Smad3 Target Gene That Regulates Lung Cancer Cell Motility via Integrin α5β1

(2012) Nikica Mise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-  and GM-CSF

(2012) P. Spear et al.   JOURNAL OF IMMUNOLOGY

Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth

(2012) E. Schlecker et al.   JOURNAL OF IMMUNOLOGY

Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

(2012) Suzanne Ostrand-Rosenberg et al.   SEMINARS IN CANCER BIOLOGY

The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages

(2012) Daria Capece et al.   Biomed Research International

Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity

(2012) LeeAnn T. Blalock et al.   OncoImmunology

IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma

(2011) Jiankun Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells

(2011) N. Obermajer et al.   BLOOD

Chronic inflammation, the tumor microenvironment and carcinogenesis

(2011) Tamas A. Gonda et al.   CELL CYCLE

Signaling Pathways Governing Tumor Angiogenesis

(2011) Toshiharu Sakurai et al.   ONCOLOGY

Knockout of HIF-1  in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

(2010) C. Werno et al.   CARCINOGENESIS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Chemokines in cancer related inflammation

(2010) Paola Allavena et al.   EXPERIMENTAL CELL RESEARCH

Immune Regulation of Cancer

(2010) Mary L. Disis   JOURNAL OF CLINICAL ONCOLOGY

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

(2010) Thomas Condamine et al.   TRENDS IN IMMUNOLOGY

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

Inflammation and colorectal cancer

(2009) Sarah Kraus et al.   CURRENT OPINION IN PHARMACOLOGY

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

(2009) Andrew J. Fleetwood et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

CD163, a Marker of Perivascular Macrophages, Is Up-Regulated by Microglia in Simian Immunodeficiency Virus Encephalitis after Haptoglobin-Hemoglobin Complex Stimulation and Is Suggestive of Breakdown of the Blood-Brain Barrier

(2008) Juan T. Borda et al.   AMERICAN JOURNAL OF PATHOLOGY

Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?

(2008) Sergei Grivennikov et al.   CANCER CELL

Cancer related inflammation: The macrophage connection

(2008) Antonio Sica et al.   CANCER LETTERS

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells

(2008) Ilaria Marigo et al.   IMMUNOLOGICAL REVIEWS

Tumor-Associated Macrophage-Induced Invasion and Angiogenesis of Human Basal Cell Carcinoma Cells by Cyclooxygenase-2 Induction

(2008) Jeng-Wei Tjiu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling

(2008) Stephen F. Badylak et al.   TISSUE ENGINEERING PART A

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark