Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Authors
Keywords
CSF1, CSF1R, Tumor-associated macrophage, Clinical trial, Cancer therapy, PVNS, Dt-GCT
Journal
Journal for ImmunoTherapy of Cancer
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-06-30
DOI
10.1186/s40425-017-0257-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of the colony-stimulating factor (CSF)/CSF-1 receptor axis in cancer
- (2016) Daniela Achkova et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Effects of microsatellite instability on recurrence patterns and outcomes in colorectal cancers
- (2016) Chang Gon Kim et al. BRITISH JOURNAL OF CANCER
- Abstract CT137: First-in-human study of AMG 820, a monoclonal anti-CSF-1R (c-fms) antibody, in patients (pts) with advanced solid tumors
- (2016) Kyriakos Papadopoulos et al. CANCER RESEARCH
- Patient-reported Symptoms of Tenosynovial Giant Cell Tumors
- (2016) Heather L. Gelhorn et al. CLINICAL THERAPEUTICS
- Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability
- (2016) Bernhard Mlecnik et al. IMMUNITY
- Tumor macrophages are pivotal constructors of tumor collagenous matrix
- (2016) Ran Afik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
- (2016) Roy S Herbst et al. LANCET
- Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
- (2016) Jonathan E Rosenberg et al. LANCET
- Macrophage Susceptibility to Emactuzumab (RG7155) Treatment
- (2016) Leon P. Pradel et al. MOLECULAR CANCER THERAPEUTICS
- TAM receptors regulate multiple features of microglial physiology
- (2016) Lawrence Fourgeaud et al. NATURE
- The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis
- (2016) Ido Amit et al. NATURE IMMUNOLOGY
- Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
- (2016) Robert L. Ferris et al. NEW ENGLAND JOURNAL OF MEDICINE
- The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
- (2016) D. F. Quail et al. SCIENCE
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- Abstract B143: A phase 1a/1b study of FPA008 in combination with nivolumab in patients with selected advanced cancers
- (2016) Julie Brahmer et al. Cancer Immunology Research
- Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors
- (2016) Rikke B. Holmgaard et al. EBioMedicine
- 18TiP * Phase 1/2a study of double immune suppression blockade by combining a CSF1R inhibitor (pexidartinib/PLX3397) with an anti PD-1 antibody (pembrolizumab) to treat advanced melanoma and other solid tumors
- (2015) S. Hu-Lieskovan et al. ANNALS OF ONCOLOGY
- An Open-Label, Multicenter, Phase I/II Study of JNJ-40346527, a CSF-1R Inhibitor, in Patients with Relapsed or Refractory Hodgkin Lymphoma
- (2015) B. von Tresckow et al. CLINICAL CANCER RESEARCH
- Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy
- (2015) M. C. Genovese et al. JOURNAL OF RHEUMATOLOGY
- CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study
- (2015) Philippe A Cassier et al. LANCET ONCOLOGY
- Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
- (2015) Nicholas Butowski et al. NEURO-ONCOLOGY
- Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor
- (2015) William D. Tap et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab in Previously Untreated Melanoma without BRAF Mutation
- (2015) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
- (2015) Stephen M. Ansell et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Macrophages and cancer: from mechanisms to therapeutic implications
- (2015) Renato Ostuni et al. TRENDS IN IMMUNOLOGY
- The Microsatellite Instable Subset of Colorectal Cancer Is a Particularly Good Candidate for Checkpoint Blockade Immunotherapy
- (2015) Yanping Xiao et al. Cancer Discovery
- Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
- (2014) Carola H. Ries et al. CANCER CELL
- High intratumoral macrophage content is an adverse prognostic feature in anaplastic large cell lymphoma
- (2014) Martin B Pedersen et al. HISTOPATHOLOGY
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Abstract A252: A phase 1 study of ARRY-382, an oral inhibitor of colony-stimulating factor-1 receptor (CSF1R), in patients with advanced or metastatic cancers.
- (2014) J. C. Bendell et al. MOLECULAR CANCER THERAPEUTICS
- Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
- (2014) Calum C Bain et al. NATURE IMMUNOLOGY
- Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
- (2014) Christoph Schneider et al. NATURE IMMUNOLOGY
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- CSF-1 Receptor Signaling in Myeloid Cells
- (2014) E. R. Stanley et al. Cold Spring Harbor Perspectives in Biology
- Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
- (2013) S. Mok et al. CANCER RESEARCH
- M1 and M2 Macrophages: Oracles of Health and Disease
- (2013) Charles Mills CRITICAL REVIEWS IN IMMUNOLOGY
- Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives
- (2013) Rashmi R. Shah et al. DRUG SAFETY
- Macrophages promote tumour growth and liver metastasis in an orthotopic syngeneic mouse model of colon cancer
- (2013) J. Kruse et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function
- (2013) Atsushi Nakamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
- (2013) Martin Guilliams et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Distribution and Alteration of Lymphatic Vessels in Knee Joints of Normal and Osteoarthritic Mice
- (2013) Jixiang Shi et al. Arthritis & Rheumatology
- Activating Mutations in β-Catenin in Colon Cancer Cells Alter Their Interaction with Macrophages; the Role of Snail
- (2012) Pawan Kaler et al. PLoS One
- Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature
- (2012) Qiong-wen Zhang et al. PLoS One
- Increased Serum Enzyme Levels Associated with Kupffer Cell Reduction with No Signs of Hepatic or Skeletal Muscle Injury
- (2011) Zaher A. Radi et al. AMERICAN JOURNAL OF PATHOLOGY
- Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation
- (2011) Jason C Lenzo et al. IMMUNOLOGY AND CELL BIOLOGY
- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
- (2011) Bin-Zhi Qian et al. NATURE
- Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
- (2011) Bryna Erblich et al. PLoS One
- An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation
- (2010) K. P. A. MacDonald et al. BLOOD
- The myeloid cells of the central nervous system parenchyma
- (2010) Richard M. Ransohoff et al. NATURE
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
- (2008) Y Komohara et al. JOURNAL OF PATHOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now