O-GlcNAcylation and O-GlcNAc Cycling Regulate Gene Transcription: Emerging Roles in Cancer
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
O-GlcNAcylation and O-GlcNAc Cycling Regulate Gene Transcription: Emerging Roles in Cancer
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 7, Pages 1666
Publisher
MDPI AG
Online
2021-04-01
DOI
10.3390/cancers13071666
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Understanding the Role of the Transcription Factor Sp1 in Ovarian Cancer: from Theory to Practice
- (2020) Vellingiri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters
- (2020) Mathieu Boulard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nutrient Regulation of Signaling & Transcription
- (2019) Gerald W. Hart JOURNAL OF BIOLOGICAL CHEMISTRY
- Resistance to bortezomib in breast cancer cells that downregulate Bim through FOXA1 O-GlcNAcylation
- (2019) Yubo Liu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- O‐GlcNAc transferase activates stem‐like cell potential in hepatocarcinoma through O‐GlcNAcylation of eukaryotic initiation factor 4E
- (2019) Benjin Cao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
- (2019) Neha M. Akella et al. BMC BIOLOGY
- Correction: O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit
- (2019) Mingzuo Jiang et al. ONCOGENE
- Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders
- (2019) Anke Hoffmann et al. Frontiers in Genetics
- TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation
- (2019) Stéphan Hardivillé et al. MOLECULAR CELL
- 2-Deoxy- d -glucose increases GFAT1 phosphorylation resulting in endoplasmic reticulum-related apoptosis via disruption of protein N -glycosylation in pancreatic cancer cells
- (2018) Kousuke Ishino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression
- (2018) Susanne Bornelöv et al. MOLECULAR CELL
- Impact of OGT deregulation on EZH2 target genes FOXA1 and FOXC1 expression in breast cancer cells
- (2018) Ewa Forma et al. PLoS One
- Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins
- (2018) Clifford A. Toleman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2
- (2018) Pei-Wen Lo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring
- (2018) Ferdinando Chiaradonna et al. Cells
- Proteomic analysis of the OGT interactome: novel links to epithelial–mesenchymal transition and metastasis of cervical cancer
- (2018) Jie Gao et al. CARCINOGENESIS
- O-GlcNAc homeostasis contributes to cell fate decisions during hematopoiesis
- (2018) Zhen Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity
- (2018) Shamik Das et al. LABORATORY INVESTIGATION
- Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy
- (2018) Gwendoline Bourré et al. Frontiers in Endocrinology
- O-GlcNAc transferase regulates transcriptional activity of human Oct4
- (2017) Sandii Constable et al. GLYCOBIOLOGY
- Nutrient-drivenO-linkedN-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism
- (2017) Stephanie Olivier-Van Stichelen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation
- (2017) Changmin Peng et al. MOLECULAR CELL
- Protein O-GlcNAcylation: emerging mechanisms and functions
- (2017) Xiaoyong Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation
- (2017) Aneika C. Leney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
- (2017) Xiao Zhang et al. Nature Communications
- O-GlcNAc-Dependent Regulation of Progesterone Receptor Function in Breast Cancer
- (2017) Gloria M. Trinca et al. Hormones & Cancer
- Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway
- (2017) A Vasconcelos-dos-Santos et al. Oncogenesis
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- O-LinkedN-Acetylglucosamine (O-GlcNAc) Transferase andO-GlcNAcase Interact with Mi2β Protein at theAγ-Globin Promoter
- (2016) Zhen Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human RNA Polymerase II Promoter Recruitmentin VitroIs Regulated byO-LinkedN-Acetylglucosaminyltransferase (OGT)
- (2016) Brian A. Lewis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAcase Is an RNA Polymerase II Elongation Factor Coupled to Pausing Factors SPT5 and TIF1β
- (2016) Melissa Resto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DrosophilaO-GlcNAcase Deletion Globally Perturbs ChromatinO-GlcNAcylation
- (2016) Ilhan Akan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide chemical mapping of O-GlcNAcylated proteins in Drosophila melanogaster
- (2016) Ta-Wei Liu et al. Nature Chemical Biology
- A High-Density Map for Navigating the Human Polycomb Complexome
- (2016) Simon Hauri et al. Cell Reports
- Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway
- (2016) Cédric Chaveroux et al. Scientific Reports
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- Genesis of Chromatin and Transcription Dynamics in the Origin of Species
- (2015) Maria J.E. Koster et al. CELL
- You are what you eat
- (2015) Stéphanie Olivier-Van Stichelen et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Phosphorylation of TET Proteins Is Regulated viaO-GlcNAcylation by theO-LinkedN-Acetylglucosamine Transferase (OGT)
- (2015) Christina Bauer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conditional Knock-out Reveals a Requirement forO-LinkedN-Acetylglucosaminase (O-GlcNAcase) in Metabolic Homeostasis
- (2015) Chithra Keembiyehetty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity
- (2015) Lily L. Jin et al. MOLECULAR & CELLULAR PROTEOMICS
- mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer
- (2015) V. L. Sodi et al. MOLECULAR CANCER RESEARCH
- Function and information content of DNA methylation
- (2015) Dirk Schübeler NATURE
- Identification and characterization of essential genes in the human genome
- (2015) T. Wang et al. SCIENCE
- RING1B O-GlcNAcylation regulates gene targeting of polycomb repressive complex 1 in human embryonic stem cells
- (2015) Julien Jean Pierre Maury et al. Stem Cell Research
- The nucleosome remodeling and deacetylase complex in development and disease
- (2015) Jeannine Basta et al. Translational Research
- Identification of Kinase Inhibitors that Target Transcription Initiation by RNA Polymerase II
- (2015) José M. Morachis et al. Oncotarget
- Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
- (2014) Zhao V. Wang et al. CELL
- Looping Back to Leap Forward: Transcription Enters a New Era
- (2014) Michael Levine et al. CELL
- Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation
- (2014) Stéphan Hardivillé et al. Cell Metabolism
- The potential role of O-GlcNAc modification in cancer epigenetics
- (2014) Ewa Forma et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- O-GlcNAc and the Epigenetic Regulation of Gene Expression
- (2014) Brian A. Lewis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Hippo-YAP signaling pathway and contact inhibition of growth
- (2014) Barry M. Gumbiner et al. JOURNAL OF CELL SCIENCE
- O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway
- (2014) Christina M. Ferrer et al. MOLECULAR CELL
- Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer
- (2014) Anne Benard et al. PLoS One
- O-GlcNAcylation regulates EZH2 protein stability and function
- (2014) C.-S. Chu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAcase Expression is Sensitive to Changes in O-GlcNAc Homeostasis
- (2014) Zhen Zhang et al. Frontiers in Endocrinology
- Probing the Hexosamine Biosynthetic Pathway in Human Tumor Cells by Multitargeted Tandem Mass Spectrometry
- (2013) Anas M. Abdel Rahman et al. ACS Chemical Biology
- O-GlcNAc in cancer biology
- (2013) Zhiyuan Ma et al. AMINO ACIDS
- O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease
- (2013) Michelle R. Bond et al. Annual Review of Nutrition
- TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
- (2013) Rachel Deplus et al. EMBO JOURNAL
- Deciphering post-translational modification codes
- (2013) Adam P. Lothrop et al. FEBS LETTERS
- Triptolide-induced Cell Death in Pancreatic Cancer Is Mediated byO-GlcNAc Modification of Transcription Factor Sp1
- (2013) Sulagna Banerjee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteomic analysis and abrogated expression ofO-GlcNAcylated proteins associated with primary breast cancer
- (2013) Voraratt Champattanachai et al. PROTEOMICS
- O-GlcNAcylation: A New Cancer Hallmark?
- (2013) Yann Fardini et al. Frontiers in Endocrinology
- Evidence of the Involvement ofO-GlcNAc-modified Human RNA Polymerase II CTD in Transcriptionin Vitroandin Vivo
- (2012) Stella M. Ranuncolo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TET2 promotes histone O-GlcNAcylation during gene transcription
- (2012) Qiang Chen et al. NATURE
- The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
- (2012) J. M. Lamar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease
- (2011) Gerald W. Hart et al. Annual Review of Biochemistry
- Gene expression of O-GlcNAc cycling enzymes in human breast cancers
- (2011) Anna Krześlak et al. CLINICAL AND EXPERIMENTAL MEDICINE
- O-Linked-N-Acetylglucosamine Cycling and Insulin Signaling Are Required for the Glucose Stress Response inCaenorhabditis elegans
- (2011) Michelle A. Mondoux et al. GENETICS
- The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
- (2011) Bin Zhao et al. NATURE CELL BIOLOGY
- Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells
- (2011) S. A. Myers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of transcription factor function by O-GlcNAc modification
- (2010) Sabire Özcan et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- GlcNAcylation Plays an Essential Role in Breast Cancer Metastasis
- (2010) Y. Gu et al. CANCER RESEARCH
- The Role of the O-GlcNAc Modification in Regulating Eukaryotic Gene Expression
- (2010) Sandii Brimble et al. Current Signal Transduction Therapy
- Hippo signaling: growth control and beyond
- (2010) G. Halder et al. DEVELOPMENT
- The Hippo Signaling Pathway in Development and Cancer
- (2010) Duojia Pan DEVELOPMENTAL CELL
- The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- O-GlcNAc Transferase Regulates Mitotic Chromatin Dynamics
- (2010) Kaoru Sakabe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-Linked β-N-acetylglucosamine (O-GlcNAc) Regulates Stress-induced Heat Shock Protein Expression in a GSK-3β-dependent Manner
- (2010) Zahra Kazemi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
- (2010) S A Caldwell et al. ONCOGENE
- Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity
- (2010) D. C. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -N-acetylglucosamine (O-GlcNAc) is part of the histone code
- (2010) K. Sakabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-GlcNAc signaling: a metabolic link between diabetes and cancer?
- (2010) C. Slawson et al. TRENDS IN BIOCHEMICAL SCIENCES
- The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
- (2009) John A. Hanover et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Epigenetics in cancer
- (2009) S. Sharma et al. CARCINOGENESIS
- Structural differentiation of the three eukaryotic RNA polymerases
- (2009) Robert Carter et al. GENOMICS
- Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression
- (2009) Maria Cristina Gambetta et al. SCIENCE
- Keeping things quiet: Roles of NuRD and Sin3 co-repressor complexes during mammalian development
- (2008) Patrick McDonel et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cross-talk between GlcNAcylation and phosphorylation: Site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc
- (2008) Z. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More