Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease

(2019) Lyssia Belarif et al.   JOURNAL OF CLINICAL INVESTIGATION

The Regulation of Inflammation by Innate and Adaptive Lymphocytes

(2018) David Alex Cronkite et al.   Journal of Immunology Research

Thymic Stromal Lymphopoietin Isoforms, Inflammatory Disorders, and Cancer

(2018) Gilda Varricchi et al.   Frontiers in Immunology

Regulatory T cells in the treatment of disease

(2018) Amir Sharabi et al.   NATURE REVIEWS DRUG DISCOVERY

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates

(2018) Lyssia Belarif et al.   Nature Communications

The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases

(2017) Brad Griesenauer et al.   Frontiers in Immunology

CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata

(2016) Zhenpeng Dai et al.   JOURNAL OF IMMUNOLOGY

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?

(2016) Anabelle Visperas et al.   JOURNAL OF IMMUNOLOGY

Unstable FoxP3+T regulatory cells in NZW mice

(2016) Fabien Dépis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis

(2015) Carlos A. Arbelaez et al.   JOURNAL OF IMMUNOLOGY

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis

(2015) Philip J. Mease et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-7 receptor blockade following T cell depletion promotes long-term allograft survival

(2014) Hoa-Le Mai et al.   JOURNAL OF CLINICAL INVESTIGATION

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

(2014) Luzhou Xing et al.   NATURE MEDICINE

Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata

(2014) Emeline Castela et al.   JAMA Dermatology

Interleukin-7 Enhances the Th1 Response to Promote the Development of Sjögren's Syndrome-like Autoimmune Exocrinopathy in Mice

(2013) Jun-O Jin et al.   ARTHRITIS AND RHEUMATISM

IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R

(2013) C. E. Martin et al.   BLOOD

Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy

(2013) Spencer C. Liang et al.   CLINICAL IMMUNOLOGY

What causes alopecia areata?

(2013) K. J. McElwee et al.   EXPERIMENTAL DERMATOLOGY

Interleukin-7: Fuel for the autoimmune attack

(2013) Hans Dooms   JOURNAL OF AUTOIMMUNITY

Janus-like effects of type I interferon in autoimmune diseases

(2012) Robert C. Axtell et al.   IMMUNOLOGICAL REVIEWS

T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice

(2012) Matthew L. Bettini et al.   IMMUNOLOGY

Identification of IL-7-Producing Cells in Primary and Secondary Lymphoid Organs Using IL-7-GFP Knock-In Mice

(2012) T. Hara et al.   JOURNAL OF IMMUNOLOGY

Alopecia Areata

(2012) Amos Gilhar et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells

(2012) C. Penaranda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis

(2012) Florent Carrette et al.   SEMINARS IN IMMUNOLOGY

The human IL-7 receptor gene: Deletions, polymorphisms and mutations

(2012) Renata I. Mazzucchelli et al.   SEMINARS IN IMMUNOLOGY

Suppression assays with human T regulatory cells: A technical guide

(2011) Alicia N. McMurchy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Mouse Model of Clonal CD8+ T Lymphocyte-Mediated Alopecia Areata Progressing to Alopecia Universalis

(2011) R. Alli et al.   JOURNAL OF IMMUNOLOGY

IL-7 Promotes TH1 Development and Serum IL-7 Predicts Clinical Response to Interferon-  in Multiple Sclerosis

(2011) L.-F. Lee et al.   Science Translational Medicine

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

(2010) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Commensal microflora and interferon-γ promote steady-state interleukin-7 production in vivo

(2010) Shabnam Shalapour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Cutting Edge: Mechanisms of IL-2-Dependent Maintenance of Functional Regulatory T Cells

(2010) L. Barron et al.   JOURNAL OF IMMUNOLOGY

Alopecia areata update

(2010) Abdullah Alkhalifah et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

(2010) Lynn Petukhova et al.   NATURE

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

(2008) T. Calzascia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA