Glycolytic Metabolism Is Critical for the Innate Antibacterial Defense in Acute Streptococcus pneumoniae Otitis Media

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

(2018) Pedro Escoll et al.   FEBS Journal

Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis

(2018) Ru-Tao Liu et al.   Journal of Neuroinflammation

HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection

(2018) Chunxiao Li et al.   Scientific Reports

Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells

(2017) Sofia Pavlou et al.   Journal of Inflammation-London

Hypoxia and HIF-1 activation in bacterial infections

(2017) Gayatri Devraj et al.   MICROBES AND INFECTION

Hypoxia-inducible factors: key regulators of myeloid cells during inflammation

(2016) Nan Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation

(2016) Ninel Azoitei et al.   Molecular Cancer

TLR2 promotes macrophage recruitment and Streptococcus pneumoniae clearance during mouse otitis media

(2016) Yifei Huang et al.   PEDIATRIC RESEARCH

HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity

(2016) Hiroaki Semba et al.   Nature Communications

Immunometabolism in Tuberculosis

(2016) Lanbo Shi et al.   Frontiers in Immunology

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Interleukin 17A Promotes Pneumococcal Clearance by Recruiting Neutrophils and Inducing Apoptosis through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism in Acute Otitis Media

(2014) W. Wang et al.   INFECTION AND IMMUNITY

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Twelve-year survey (2001–2012) of the antimicrobial susceptibility of Streptococcus pneumoniae isolates from otorhinolaryngology clinics in Miyagi Prefecture, Japan

(2014) Daiki Ozawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

The Warburg effect then and now: From cancer to inflammatory diseases

(2013) Eva M. Palsson-McDermott et al.   BIOESSAYS

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

The Diagnosis and Management of Acute Otitis Media

(2013) A. S. Lieberthal et al.   PEDIATRICS

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

(2013) Philip M. Elks et al.   PLoS Pathogens

PK-M2 Makes Cells Sweeter on HIF1

(2011) Daniel A. Tennant   CELL

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Otitis media and its consequences: beyond the earache

(2010) Anne Vergison et al.   LANCET INFECTIOUS DISEASES