Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection

(2013) Toshihiro Masaki et al.   CELL

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system

(2013) M. van der Vaart et al.   Disease Models & Mechanisms

A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis

(2012) Kirankumar Santhakumar et al.   CANCER RESEARCH

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

(2012) David M. Tobin et al.   CELL

Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages

(2012) Chao-Tsung Yang et al.   Cell Host & Microbe

Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide

(2012) Christopher J. Hall et al.   Cell Stem Cell

Infection of macrophages withMycobacterium tuberculosisinduces global modifications to phagosomal function

(2012) Maria Podinovskaia et al.   CELLULAR MICROBIOLOGY

Hooked! Modeling human disease in zebrafish

(2012) Cristina Santoriello et al.   JOURNAL OF CLINICAL INVESTIGATION

A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

(2012) Cheryl Y. M. Okumura et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Prison Break: Pathogens' Strategies To Egress from Host Cells

(2012) Nikolas Friedrich et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Insights into tuberculosis from the zebrafish model

(2012) Russell D. Berg et al.   TRENDS IN MOLECULAR MEDICINE

Mycobacterium marinum Causes a Latent Infection that Can Be Reactivated by Gamma Irradiation in Adult Zebrafish

(2012) Mataleena Parikka et al.   PLoS Pathogens

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

(2011) E. J. M. Stoop et al.   Disease Models & Mechanisms

Hypoxia-Inducible Factor-2  Regulates GM-CSF-Derived Soluble Vascular Endothelial Growth Factor Receptor 1 Production from Macrophages and Inhibits Tumor Growth and Angiogenesis

(2011) J. M. Roda et al.   JOURNAL OF IMMUNOLOGY

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

(2011) Laeticia Alibaud et al.   MOLECULAR MICROBIOLOGY

Macrophages and control of granulomatous inflammation in tuberculosis

(2011) J L Flynn et al.   Mucosal Immunology

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

Neutrophils in tuberculosis: friend or foe?

(2011) David M. Lowe et al.   TRENDS IN IMMUNOLOGY

mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish

(2010) F. Ellett et al.   BLOOD

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

(2010) David M. Tobin et al.   CELL

Differential activation and antagonistic function of HIF-  isoforms in macrophages are essential for NO homeostasis

(2010) N. Takeda et al.   GENES & DEVELOPMENT

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish

(2009) Catherine A. Loynes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components

(2009) Astrid M. van der Sar et al.   MOLECULAR IMMUNOLOGY

Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function

(2009) Sarah R Walmsley et al.   ARTHRITIS RESEARCH & THERAPY

Tumor Necrosis Factor Signaling Mediates Resistance to Mycobacteria by Inhibiting Bacterial Growth and Macrophage Death

(2008) Hilary Clay et al.   IMMUNITY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Critical Role of HIF-1α in Keratinocyte Defense against Bacterial Infection

(2008) Carole Peyssonnaux et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Differential contribution of neutrophilic granulocytes and macrophages to nitrosative stress in a host–parasite animal model

(2008) Maria Forlenza et al.   MOLECULAR IMMUNOLOGY

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages

(2008) Ludovic Tailleux et al.   PLoS One