RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain

Adenosine-to-inosine RNA editing in the immune system: friend or foe?

(2020) Taisuke Nakahama et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal

(2020) Claudio Lo Giudice et al.   Nature Protocols

A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing

(2020) Pedro Henrique Costa Cruz et al.   RNA

ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways

(2020) Tuangtong Vongpipatana et al.   JOURNAL OF IMMUNOLOGY

What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs

(2020) Jacki E. Heraud-Farlow et al.   Open Biology

The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection

(2020) Olivia A. Vogel et al.   PLoS Pathogens

Mendelian disease caused by variants affecting recognition of Z-DNA and Z-RNA by the Zα domain of the double-stranded RNA editing enzyme ADAR

(2019) Alan Herbert   EUROPEAN JOURNAL OF HUMAN GENETICS

A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing

(2019) Konstantin Licht et al.   GENOME RESEARCH

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

(2018) Hachung Chung et al.   CELL

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation

(2018) Sadeem Ahmad et al.   CELL

ADAR1‐mediated RNA editing is required for thymic self‐tolerance and inhibition of autoimmunity

(2018) Taisuke Nakahama et al.   EMBO REPORTS

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay

(2017) Masayuki Sakurai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay

(2017) Masayuki Sakurai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complex regulation of ADAR-mediated RNA-editing across tissues

(2016) Melanie A. Huntley et al.   BMC GENOMICS

CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis

(2016) Kotaro Miyake et al.   Cell Reports

Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1

(2015) Yanick J. Crow et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

(2015) Nuala A. O'Leary et al.   NUCLEIC ACIDS RESEARCH

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Widespread intron retention in mammals functionally tunes transcriptomes

(2014) Ulrich Braunschweig et al.   GENOME RESEARCH

A genome-wide map of hyper-edited RNA reveals numerous new sites

(2014) Hagit T. Porath et al.   Nature Communications

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

MicroRNA Editing Facilitates Immune Elimination of HCMV Infected Cells

(2014) Daphna Nachmani et al.   PLoS Pathogens

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

(2012) Zhiyu Peng et al.   NATURE BIOTECHNOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Accurate identification of human Alu and non-Alu RNA editing sites

(2012) Gokul Ramaswami et al.   NATURE METHODS

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

ADAR1 isoform involvement in embryonic lethality

(2011) R. A. Steinman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

(2010) S. V. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

Determination of editors at the novel A-to-I editing positions

(2008) Yoshinori Nishimoto et al.   NEUROSCIENCE RESEARCH

The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus

(2008) Lily Agranat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity of ADAR-mediated RNA editing in newly identified targets

(2008) E. M. Riedmann et al.   RNA

Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5′-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon

(2008) Cyril X. George et al.   VIROLOGY