ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways

Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses

(2019) Charles E. Samuel   JOURNAL OF BIOLOGICAL CHEMISTRY

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

(2018) Hachung Chung et al.   CELL

A-to-I RNA editing — immune protector and transcriptome diversifier

(2018) Eli Eisenberg et al.   NATURE REVIEWS GENETICS

ADAR1‐mediated RNA editing is required for thymic self‐tolerance and inhibition of autoimmunity

(2018) Taisuke Nakahama et al.   EMBO REPORTS

T time for ADAR: ADAR1 is required for T cell self‐tolerance

(2018) Hachung Chung et al.   EMBO REPORTS

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay

(2017) Masayuki Sakurai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ADAR RNA editing below the backbone

(2017) Liam Keegan et al.   RNA

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay

(2017) Masayuki Sakurai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complex regulation of ADAR-mediated RNA-editing across tissues

(2016) Melanie A. Huntley et al.   BMC GENOMICS

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis

(2016) Shirley Oren Ben-Shoshan et al.   RNA Biology

ADAR1 is vital for B cell lineage development in the mouse bone marrow

(2016) Victoria Marcu-Malina et al.   Oncotarget

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

A-to-I editing of coding and non-coding RNAs by ADARs

(2015) Kazuko Nishikura   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

An RNA Editor, Adenosine Deaminase Acting on Double-Stranded RNA (ADAR1)

(2014) Cyril X. George et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

Thymic Function Is Maintained during Salmonella -Induced Atrophy and Recovery

(2012) Ewan A. Ross et al.   JOURNAL OF IMMUNOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Activation Kinetics and Off-Target Effects of Thymus-Initiated Cre Transgenes

(2012) Jianjun Shi et al.   PLoS One

Effects of Plasmodium berghei on thymus: High levels of apoptosis and premature egress of CD4+CD8+ thymocytes in experimentally infected mice

(2011) Carolina Francelin et al.   IMMUNOBIOLOGY

Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice

(2011) P. A. Frischmeyer-Guerrerio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome

(2010) Georgia Ramantani et al.   ARTHRITIS AND RHEUMATISM

RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

(2010) S. V. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

(2008) J. Weischenfeldt et al.   GENES & DEVELOPMENT

The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus

(2008) Lily Agranat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA