Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis

Crosstalk of the Caspase Family and Mammalian Target of Rapamycin Signaling

(2021) Junfang Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of the non‐neuronal cholinergic system in inflammation and degradation processes in osteoarthritis

(2020) Alice Courties et al.   Arthritis & Rheumatology

Recombinant Analogue of the Human Protein SLURP-1 Inhibits the Growth of U251 MG and A172 Glioma Cells

(2020) M. A. Shulepko et al.   Doklady Biochemistry and Biophysics

Mitochondrial α7 nicotinic acetylcholine receptors are displaced from complexes with VDAC1 to form complexes with Bax upon apoptosis induction

(2020) Olena Kalashnyk et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of α7‐nAChRs protects SH‐SY5Y cells from 1‐methyl‐4‐phenylpyridinium‐induced apoptotic cell death via ERK/p53 signaling pathway

(2019) Shi Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Advantages and disadvantages of apoptosis in the aging process

(2019) Sandro Argüelles et al.   Annals of the New York Academy of Sciences

An In Vitro and In Vivo Comparison of Cartilage Growth in Chondrocyte-Laden Matrix Metalloproteinase-Sensitive Poly(Ethylene Glycol) Hydrogels with Localized Transforming Growth Factor β3

(2019) Margaret C. Schneider et al.   Acta Biomaterialia

MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint

(2019) Hongxu Yang et al.   Autophagy

Osteoarthritis

(2019) David J Hunter et al.   LANCET

Alpha7 Nicotinic Acetylcholine Receptor Alleviates Inflammatory Bowel Disease Through Induction of AMPK-mTOR-p70S6K-Mediated Autophagy

(2019) Bo-Zong Shao et al.   INFLAMMATION

Nicotine Attenuates Osteoarthritis Pain and Matrix Metalloproteinase-9 Expression via the α7 Nicotinic Acetylcholine Receptor

(2019) Peng Teng et al.   JOURNAL OF IMMUNOLOGY

Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors

(2019) Maxim Bychkov et al.   PLoS One

Epidemiology of osteoarthritis

(2018) Ernest R. Vina et al.   CURRENT OPINION IN RHEUMATOLOGY

Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors

(2018) Nadine Kabbani et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis

(2018) Claire Vinatier et al.   Frontiers in Physiology

Balancing the autonomic nervous system to reduce inflammation in rheumatoid arthritis

(2017) F. A. Koopman et al.   JOURNAL OF INTERNAL MEDICINE

Association between smoking and risk of knee osteoarthritis: a systematic review and meta-analysis

(2017) L. Kong et al.   OSTEOARTHRITIS AND CARTILAGE

Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction

(2017) M. Ito et al.   OSTEOARTHRITIS AND CARTILAGE

Prevalence and associated factors of knee osteoarthritis in a rural Chinese adult population: an epidemiological survey

(2015) Yuan Liu et al.   BMC PUBLIC HEALTH

Activation of a7 Nicotinic Acetylcholine Receptors Prevents Monosodium Iodoacetate-Induced Osteoarthritis in Rats

(2015) Yuan Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

(2015) Hyun Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson's disease

(2015) Yuan Liu et al.   NEUROPHARMACOLOGY

The Relationship of Autophagy Defects to Cartilage Damage During Joint Aging in a Mouse Model

(2015) Beatriz Caramés et al.   Arthritis & Rheumatology

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

(2014) Yue Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Aging Research—Where Do We Stand and Where Are We Going?

(2014) Leonard Guarente   CELL

α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways

(2014) Galyna Gergalova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nicotine-Mediated Cell Proliferation and Tumor Progression in Smoking-Related Cancers

(2014) Courtney Schaal et al.   MOLECULAR CANCER RESEARCH

Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

(2014) Koji Takayama et al.   ARTHRITIS RESEARCH & THERAPY

Boning up on autophagy

(2013) Irving M Shapiro et al.   Autophagy

Rethinking inflammation: neural circuits in the regulation of immunity

(2012) Peder S. Olofsson et al.   IMMUNOLOGICAL REVIEWS

Mitochondria Express α7 Nicotinic Acetylcholine Receptors to Regulate Ca2+ Accumulation and Cytochrome c Release: Study on Isolated Mitochondria

(2012) Galyna Gergalova et al.   PLoS One

Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor  7 subunit gene knockout mice

(2010) M. A. van Maanen et al.   ANNALS OF THE RHEUMATIC DISEASES

Selective Autophagy in Cancer Development and Therapy

(2010) Ivan Dikic et al.   CANCER RESEARCH

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis

(2009) M. Blagojevic et al.   OSTEOARTHRITIS AND CARTILAGE

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL