Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction

Title
Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction
Authors
Keywords
Intervertebral disc, Nucleus pulposus cells, Mammalian target of rapamycin (mTOR), Regulatory-associated protein of mTOR (RAPTOR), RNA interference (RNAi), Spine
Journal
OSTEOARTHRITIS AND CARTILAGE
Volume 25, Issue 12, Pages 2134-2146
Publisher
Elsevier BV
Online
2017-09-07
DOI
10.1016/j.joca.2017.08.019

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