Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity

Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells

(2020) Georgina Bowyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Malaria vaccines since 2000: progress, priorities, products

(2020) Patrick E. Duffy et al.   npj Vaccines

Immunogenicity and Protective Efficacy of Radiation-Attenuated and Chemo-Attenuated PfSPZ Vaccines in Equatoguinean Adults

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DIABLO: an integrative approach for identifying key molecular drivers from multi-omic assays

(2019) Amrit Singh et al.   BIOINFORMATICS

Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

(2019) Joshua M. Obiero et al.   mSphere

A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation

(2019) Tuan M. Tran et al.   IMMUNITY

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children

(2019) Lisa E. Wagar et al.   Frontiers in Immunology

Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoites Vaccine in Tanzanian Adults

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Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

(2018) Bertrand Lell et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence

(2018) Murad R. Mamedov et al.   IMMUNITY

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period

(2018) Julian Rothen et al.   PLoS One

Correlating efficacy and immunogenicity in malaria vaccine trials

(2018) Matthew B.B. McCall et al.   SEMINARS IN IMMUNOLOGY

Approximated and User Steerable tSNE for Progressive Visual Analytics

(2017) Nicola Pezzotti et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies

(2017) Gianna Triller et al.   IMMUNITY

γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations

(2017) Irfan Zaidi et al.   JOURNAL OF IMMUNOLOGY

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

(2017) Benjamin Mordmüller et al.   NATURE

mixOmics: An R package for ‘omics feature selection and multiple data integration

(2017) Florian Rohart et al.   PLoS Computational Biology

Longitudinal study of changes in γδ T cells and CD4+ T cells upon asymptomatic malaria infection in Indonesian children

(2017) Sanne E. de Jong et al.   Scientific Reports

Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure

(2017) Prasanna Jagannathan et al.   Scientific Reports

NKT cell subsets as key participants in liver physiology and pathology

(2016) Keya Bandyopadhyay et al.   Cellular & Molecular Immunology

Cytosplore: Interactive Immune Cell Phenotyping for Large Single-Cell Datasets

(2016) T. Höllt et al.   COMPUTER GRAPHICS FORUM

Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

(2016) Xiao Yu et al.   IMMUNITY

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

(2016) Andrew S Ishizuka et al.   NATURE MEDICINE

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria

(2016) Tuan M. Tran et al.   Scientific Reports

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression

(2015) Anne C. Teirlinck et al.   INFECTION AND IMMUNITY

Impact of Malaria Preexposure on Antiparasite Cellular and Humoral Immune Responses after Controlled Human Malaria Infection

(2015) Joshua M. Obiero et al.   INFECTION AND IMMUNITY

Plasmodium falciparumProtein Microarray Antibody Profiles Correlate With Protection From Symptomatic Malaria in Kenya

(2015) Arlene E. Dent et al.   JOURNAL OF INFECTIOUS DISEASES

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

(2015) Gloria P Gómez-Pérez et al.   MALARIA JOURNAL

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

(2015) Benjamin Mordmüller et al.   MALARIA JOURNAL

CD161intCD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut

(2015) J R Fergusson et al.   Mucosal Immunology

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK

(2014) Yun-Gyoung Hur et al.   BMC INFECTIOUS DISEASES

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine

(2014) Enoch Muyanja et al.   JOURNAL OF CLINICAL INVESTIGATION

KLRG+ invariant natural killer T cells are long-lived effectors

(2014) K. Shimizu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

(2014) Joannah R. Fergusson et al.   Cell Reports

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE)

(2013) K. Shekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

(2013) R. A. Seder et al.   SCIENCE

CD56+ monocytes have a dysregulated cytokine response to lipopolysaccharide and accumulate in rheumatoid arthritis and immunosenescence

(2013) Marco Krasselt et al.   ARTHRITIS RESEARCH & THERAPY

Pre-erythrocytic antibody profiles induced by controlled human malaria infections in healthy volunteers under chloroquine prophylaxis

(2013) Philip L. Felgner et al.   Scientific Reports

Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites

(2012) Meta Roestenberg et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion

(2012) J. Illingworth et al.   JOURNAL OF IMMUNOLOGY

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

(2011) Peng Qiu et al.   NATURE BIOTECHNOLOGY

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Memory-like IFN-γ response by NK cells following malaria infection reveals the crucial role of T cells in NK cell activation by P. falciparum

(2010) Matthew B. B. McCall et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Control of CD56 expression and tumor cell cytotoxicity in human Vγ2Vδ2 T cells

(2009) Elizabeth M Urban et al.   BMC IMMUNOLOGY

Microarray background correction: maximum likelihood estimation for the normal-exponential convolution

(2008) J. D. Silver et al.   BIOSTATISTICS

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY

Profiling humoral immune responses to P. falciparum infection with protein microarrays

(2008) Denise L. Doolan et al.   PROTEOMICS