Iron oxide nanoparticles aggravate hepatic steatosis and liver injury in nonalcoholic fatty liver disease through BMP-SMAD-mediated hepatic iron overload

NAFLD 2020: The State of the Disease

(2020) Thomas G. Cotter et al.   GASTROENTEROLOGY

Epidemiological feature of NAFLD from 1999 to 2018 in China

(2020) Jianghua Zhou et al.   HEPATOLOGY

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD

(2020) Andreea-Manuela Mirea et al.   INFLAMMATION

Mesenchymal iron deposition is associated with adverse long‐term outcome in non‐alcoholic fatty liver disease

(2020) Sebastian K. Eder et al.   LIVER INTERNATIONAL

Surface chemistry governs the sub-organ transfer, clearance and toxicity of functional gold nanoparticles in the liver and kidney

(2020) Xue Li et al.   JOURNAL OF NANOBIOTECHNOLOGY

Rapamycin-Loaded mPEG-PLGA Nanoparticles Ameliorate Hepatic Steatosis and Liver Injury in Non-alcoholic Fatty Liver Disease

(2020) Ruifang Zhao et al.   Frontiers in Chemistry

Hepatic STAMP2 mediates recombinant FGF21‐induced improvement of hepatic iron overload in nonalcoholic fatty liver disease

(2020) Hye Young Kim et al.   FASEB JOURNAL

Hepatic impacts of gold nanoparticles with different surface coatings as revealed by assessing the hepatic drug-metabolizing enzyme and lipid homeostasis in mice

(2020) Shuang Zhou et al.   NanoImpact

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

(2019) Seyed Mohammadali Dadfar et al.   ADVANCED DRUG DELIVERY REVIEWS

Iron and liver fibrosis: Mechanistic and clinical aspects

(2019) Kosha J Mehta et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Evaluating the association of serum ferritin and hepatic iron with disease severity in non‐alcoholic fatty liver disease

(2019) Elena Buzzetti et al.   LIVER INTERNATIONAL

Elimination Pathways of Nanoparticles

(2019) Wilson Poon et al.   ACS Nano

Lipogenic SREBP-1a/c transcription factors activate expression of the iron regulator hepcidin, revealing cross-talk between lipid and iron metabolisms

(2019) Alus M. Xiaoli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal Oxide Nanoparticles in Therapeutic Regulation of Macrophage Functions

(2019) Marina S. Dukhinova et al.   Nanomaterials

The role of iron in hepatic inflammation and hepatocellular carcinoma

(2018) Koji Miyanishi et al.   FREE RADICAL BIOLOGY AND MEDICINE

DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease

(2018) Hanqing Chen et al.   HEPATOLOGY

Biodistribution, pharmacokinetics, and toxicity of dendrimer-coated iron oxide nanoparticles in BALB/c mice

(2018) Marzieh Salimi et al.   International Journal of Nanomedicine

Triggering and resolution of inflammation in NASH

(2018) Susanne Schuster et al.   Nature Reviews Gastroenterology & Hepatology

Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

(2018) Zobair Younossi et al.   HEPATOLOGY

Very small superparamagnetic iron oxide nanoparticles: Long-term fate and metabolic processing in atherosclerotic mice

(2018) Wolfram C. Poller et al.   Nanomedicine-Nanotechnology Biology and Medicine

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Effect of iron on cholesterol 7α-hydroxylase expression in alcohol-induced hepatic steatosis in mice

(2017) Huan Liang et al.   JOURNAL OF LIPID RESEARCH

Hepatic iron is the major determinant of serum ferritin in NAFLD patients

(2017) John D. Ryan et al.   LIVER INTERNATIONAL

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice

(2016) Priya Handa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

For Better or Worse, Iron Overload by Superparamagnetic Iron Oxide Nanoparticles as a MRI Contrast Agent for Chronic Liver Diseases

(2016) Qibing Zhou et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model

(2016) Takumu Hasebe et al.   JOURNAL OF GASTROENTEROLOGY

Mechanism of hard-nanomaterial clearance by the liver

(2016) Kim M. Tsoi et al.   NATURE MATERIALS

Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study

(2016) Loek P. Smits et al.   RADIOLOGY

Iron and non-alcoholic fatty liver disease

(2016) Laurence J Britton et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Iron overload by Superparamagnetic Iron Oxide Nanoparticles is a High Risk Factor in Cirrhosis by a Systems Toxicology Assessment

(2016) Yushuang Wei et al.   Scientific Reports

Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload

(2015) Subhash K. Das et al.   LIVER INTERNATIONAL

Emerging applications for ferumoxytol as a contrast agent in MRI

(2014) Mustafa R. Bashir et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Oral magnetite nanoparticles disturb the development ofDrosophila melanogasterfrom oogenesis to adult emergence

(2014) Hanqing Chen et al.   Nanotoxicology

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Hepatic reticuloendothelial system cell iron deposition is associated with increased apoptosis in nonalcoholic fatty liver disease

(2013) Bryan D. Maliken et al.   HEPATOLOGY

Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis

(2012) Umbreen Ahmed   WORLD JOURNAL OF GASTROENTEROLOGY

Ferumoxytol as an Intravenous Iron Replacement Therapy in Hemodialysis Patients

(2009) R. Provenzano et al.   Clinical Journal of the American Society of Nephrology