Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction
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Title
Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction
Authors
Keywords
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Journal
MOLECULES
Volume 26, Issue 6, Pages 1613
Publisher
MDPI AG
Online
2021-03-15
DOI
10.3390/molecules26061613
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Note: Only part of the references are listed.- The effects of phytoestrogens on postmenopausal health
- (2021) I. J. Rowe et al. CLIMACTERIC
- The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis
- (2020) Marianna Talia et al. Cells
- Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
- (2020) Jing Luo et al. Frontiers in Endocrinology
- Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor β
- (2020) Benqiang Yao et al. JOURNAL OF MOLECULAR BIOLOGY
- Computational Approaches for the Discovery of GPER Targeting Compounds
- (2020) Fedora Grande et al. Frontiers in Endocrinology
- Perspectives on the Role of Non-Coding RNAs in the Regulation of Expression and Function of the Estrogen Receptor
- (2020) Mohammad Taheri et al. Cancers
- Disruption of classical estrogenic targets in brown trout primary hepatocytes by the model androgens testosterone and dihydrotestosterone
- (2020) Célia Lopes et al. AQUATIC TOXICOLOGY
- Identification of a natural compound, sesamin, as a novel TRPM8 antagonist with inhibitory effects on prostate adenocarcinoma
- (2020) Yutong Sui et al. FITOTERAPIA
- Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review
- (2020) Inés Domínguez-López et al. Nutrients
- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
- (2019) Ying Yin et al. SCIENCE
- Structural insights into the activation of metabotropic glutamate receptors
- (2019) Antoine Koehl et al. NATURE
- Effects of phytoestrogens on the activity and growth of primary breast cancer cells ex vivo
- (2019) Fang‐Ping Chen et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)
- (2019) Francesca Cirillo et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Structural insights into TRPM8 inhibition and desensitization
- (2019) Melinda M. Diver et al. SCIENCE
- Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
- (2018) Tomasz Maciej Stepniewski et al. BIOORGANIC & MEDICINAL CHEMISTRY
- ZIP9, a novel membrane androgen receptor and zinc transporter protein
- (2018) Peter Thomas et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism
- (2018) Jing Luo et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- GPCR6A Is a Molecular Target for the Natural Products Gallate and EGCG in Green Tea
- (2018) Min Pi et al. MOLECULAR NUTRITION & FOOD RESEARCH
- TRPM8 and prostate: a cold case?
- (2018) Lucile Noyer et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Structural Changes Due to Antagonist Binding in Ligand Binding Pocket of Androgen Receptor Elucidated Through Molecular Dynamics Simulations
- (2018) Sugunadevi Sakkiah et al. Frontiers in Pharmacology
- ZIP9 but not the androgen receptor mediates testosterone-induced migratory activity of metastatic prostate cancer cells
- (2018) Ahmed Bulldan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Possible role of phytoestrogens in breast cancer via GPER-1/GPR30 signaling
- (2018) Luis Molina et al. CLINICAL SCIENCE
- Food components and contaminants as (anti)androgenic molecules
- (2017) Daniele Marcoccia et al. Genes and Nutrition
- CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model
- (2017) Ruisong Ye et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Estrogens in Male Physiology
- (2017) Paul S. Cooke et al. PHYSIOLOGICAL REVIEWS
- Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1
- (2017) Francesca Spyrakis et al. ACS Medicinal Chemistry Letters
- Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer
- (2017) Konstantina Kalyvianaki et al. Scientific Reports
- Food components and contaminants as (anti)androgenic molecules
- (2017) Daniele Marcoccia et al. Genes and Nutrition
- Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway
- (2017) Tuo Zhang et al. Science Advances
- Development of Novel Cell Lines for High-Throughput Screening to Detect Estrogen-Related Receptor Alpha Modulators
- (2017) Christina T. Teng et al. SLAS Discovery
- Non-classical testosterone signaling mediated through ZIP9 stimulates claudin expression and tight junction formation in Sertoli cells
- (2016) Ahmed Bulldan et al. CELLULAR SIGNALLING
- Evaluation of OASIS QSAR Models Using ToxCast™ in Vitro Estrogen and Androgen Receptor Binding Data and Application in an Integrated Endocrine Screening Approach
- (2016) Barun Bhhatarai et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Homology Modeling, Validation and Dynamics of the G Protein-coupled Estrogen Receptor 1 (GPER-1)
- (2016) Agostino Bruno et al. Molecular Informatics
- Expression and regulation of the estrogen receptors in PC-3 human prostate cancer cells
- (2016) R. Pisolato et al. STEROIDS
- Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants
- (2016) Patricia Rueda et al. PLoS One
- Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease
- (2015) Janice M. Huss et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Non-classical testosterone signaling in spermatogenic GC-2 cells is mediated through ZIP9 interacting with Gnα11
- (2015) Mazen Shihan et al. CELLULAR SIGNALLING
- Deciphering the GPER/GPR30-agonist and antagonists interactions using molecular modeling studies, molecular dynamics, and docking simulations
- (2015) D. Méndez-Luna et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- OxeR1 regulates angiotensin II and cAMP-stimulated steroid production in human H295R adrenocortical cells
- (2015) Melina Dattilo et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Structural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral Tissues
- (2015) Min Pi et al. MOLECULAR ENDOCRINOLOGY
- Identification of the G protein-coupled estrogen receptor (GPER) in human prostate: expression site of the estrogen receptor in the benign and neoplastic gland
- (2015) V. Rago et al. Andrology
- Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and Invasion
- (2015) Nelson Yee Cancers
- Intracellular Distribution and Biological Effects of Phytochemicals in a Sex Steroid- Sensitive Model of Human Prostate Adenocarcinoma
- (2014) Antonella Smeriglio et al. Anti-Cancer Agents in Medicinal Chemistry
- Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review
- (2014) M-n. Chen et al. CLIMACTERIC
- Identification and Characterization of Membrane Androgen Receptors in the ZIP9 Zinc Transporter Subfamily: II. Role of Human ZIP9 in Testosterone-Induced Prostate and Breast Cancer Cell Apoptosis
- (2014) Peter Thomas et al. ENDOCRINOLOGY
- Identification and Characterization of Membrane Androgen Receptors in the ZIP9 Zinc Transporter Subfamily: I. Discovery in Female Atlantic Croaker and Evidence ZIP9 Mediates Testosterone-Induced Apoptosis of Ovarian Follicle Cells
- (2014) A. Håkan Berg et al. ENDOCRINOLOGY
- G Protein-Coupled Receptors: Extranuclear Mediators for the Non-Genomic Actions of Steroids
- (2014) Chen Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The TRPM8 Protein Is a Testosterone Receptor
- (2014) Swapna Asuthkar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The TRPM8 Protein Is a Testosterone Receptor
- (2014) Swapna Asuthkar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G Protein–Coupled Estrogen Receptor Regulates Mammary Tumorigenesis and Metastasis
- (2014) Nicole A. Marjon et al. MOLECULAR CANCER RESEARCH
- Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis
- (2014) Cheng-Lung Hsu et al. Molecular Oncology
- Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network
- (2014) Jerome C Nwachukwu et al. eLife
- GPER Function in Breast Cancer: An Overview
- (2014) Rosamaria Lappano et al. Frontiers in Endocrinology
- Resveratrol inhibits Kv2.2 currents through the estrogen receptor GPR30-mediated PKC pathway
- (2013) Wen-Hao Dong et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The GPCR, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function
- (2013) C Clemmensen et al. BRITISH JOURNAL OF PHARMACOLOGY
- OXER1, a G protein-coupled oxoeicosatetraenoid receptor, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells
- (2013) Sivalokanathan Sarveswaran et al. CANCER LETTERS
- Multiligand Specificity and Wide Tissue Expression of GPRC6A Reveals New Endocrine Networks
- (2012) Min Pi et al. ENDOCRINOLOGY
- A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer
- (2012) Stefanie Blättermann et al. Nature Chemical Biology
- Menthol Inhibits the Proliferation and Motility of Prostate Cancer DU145 Cells
- (2012) Yongzhi Wang et al. PATHOLOGY & ONCOLOGY RESEARCH
- Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes
- (2012) V. Delfosse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of Androgen Receptor Antagonism by Bicalutamide in the Treatment of Prostate Cancer
- (2011) D. J. Osguthorpe et al. BIOCHEMISTRY
- Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors
- (2011) Juliette Descoeur et al. EMBO Molecular Medicine
- GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo
- (2011) Min Pi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Unexpected Binding Orientation of Bulky-B-Ring Anti-Androgens and Implications for Future Drug Targets
- (2011) Charles B. Duke et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibitors of Androgen Receptor Activation Function-2 (AF2) Site Identified through Virtual Screening
- (2011) Peter Axerio-Cilies et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening.
- (2011) Nathan A. Lack et al. JOURNAL OF MEDICINAL CHEMISTRY
- GPRC6A regulates prostate cancer progression
- (2011) Min Pi et al. PROSTATE
- Xeno-oestrogens and phyto-oestrogens are alternative ligands for the androgen receptor
- (2010) Hao Wang et al. ASIAN JOURNAL OF ANDROLOGY
- Bisphenol A induces a rapid activation of Erk1/2 through GPR30 in human breast cancer cells
- (2010) S. Dong et al. ENVIRONMENTAL POLLUTION
- Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor
- (2010) X. Edward Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Minireview: Extranuclear Steroid Receptors: Roles in Modulation of Cell Functions
- (2010) Ellis R. Levin MOLECULAR ENDOCRINOLOGY
- A Phase II Trial of a Soy Beverage for Subjects Without Clinical Disease With Rising Prostate-Specific Antigen After Radical Radiation for Prostate Cancer
- (2010) Winkle Kwan et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
- (2010) B. Wu et al. SCIENCE
- Alternative Inhibition of Androgen Receptor Signaling: Peptidomimetic Pyrimidines As Direct Androgen Receptor/Coactivator Disruptors
- (2009) Jillian R. Gunther et al. ACS Chemical Biology
- Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
- (2009) Deo Prakash Pandey et al. EMBO JOURNAL
- BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis
- (2009) Xianwang Wang et al. FEBS LETTERS
- GPR30 predicts poor survival for ovarian cancer
- (2009) Harriet O. Smith et al. GYNECOLOGIC ONCOLOGY
- Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists
- (2009) J. D. Joseph et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 5-Oxo-ETE and the OXE receptor
- (2009) Gail E. Grant et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy
- (2008) John M Pendleton et al. BMC CANCER
- A Novel Dietary Flavonoid Fisetin Inhibits Androgen Receptor Signaling and Tumor Growth in Athymic Nude Mice
- (2008) N. Khan et al. CANCER RESEARCH
- Communication between the ERRα Homodimer Interface and the PGC-1α Binding Surface via the Helix 8–9 Loop
- (2008) Holger Greschik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Soy, isoflavones, and prostate cancer
- (2008) Le Jian MOLECULAR NUTRITION & FOOD RESEARCH
- NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
- (2008) Kendall W Nettles et al. Nature Chemical Biology
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