Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
Authors
Keywords
-
Journal
Frontiers in Endocrinology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-03-31
DOI
10.3389/fendo.2020.00148
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology
- (2020) Michaël Trichet et al. Cells
- Estrogen regulates forkhead transcription factor 2 to promote apoptosis of human ovarian granulosa-like tumor cells
- (2019) Jun Wu et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells
- (2019) Rosamaria Lappano et al. Cells
- G protein‐coupled oestrogen receptor stimulation ameliorates iron‐ and ovariectomy‐induced memory impairments through the cAMP / PKA / CREB signalling pathway
- (2019) Gustavo Dalto Barroso Machado et al. JOURNAL OF NEUROENDOCRINOLOGY
- G Protein-Coupled Estrogen Receptor Protects From Angiotensin II-Induced Increases in Pulse Pressure and Oxidative Stress
- (2019) Benard O. Ogola et al. Frontiers in Endocrinology
- Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism
- (2018) Jing Luo et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Genistein, a Soy Phytoestrogen, Upregulates the Expression of Human Endothelial Nitric Oxide Synthase and Lowers Blood Pressure in Spontaneously Hypertensive Rats
- (2018) Hongwei Si et al. JOURNAL OF NUTRITION
- Possible role of phytoestrogens in breast cancer via GPER-1/GPR30 signaling
- (2018) Luis Molina et al. CLINICAL SCIENCE
- G protein-coupled estrogen receptor activates cell type specific signaling pathways in cortical cultures: relevance to the selective loss of astrocytes
- (2018) C Roque et al. JOURNAL OF NEUROCHEMISTRY
- The Neuroprotective Effects of 17β-Estradiol Pretreatment in a Model of Neonatal Hippocampal Injury Induced by Trimethyltin
- (2018) Elisa Marchese et al. Frontiers in Cellular Neuroscience
- GPER modulates tone and coronary vascular reactivity in male and female rats
- (2017) Angelina Rafaela Debortoli et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The potential health effects of dietary phytoestrogens
- (2016) Ivonne M C M Rietjens et al. BRITISH JOURNAL OF PHARMACOLOGY
- Membrane and nuclear estrogen receptor α collaborate to suppress adipogenesis but not triglyceride content
- (2016) Ali Pedram et al. FASEB JOURNAL
- 17 -Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms
- (2016) J. Kim et al. JOURNAL OF NEUROSCIENCE
- GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts
- (2016) Assunta Pisano et al. MOLECULAR CARCINOGENESIS
- The molecular mechanisms underlying the ERα-36-mediated signaling in breast cancer
- (2016) S Omarjee et al. ONCOGENE
- GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
- (2016) Aihua Wang et al. Scientific Reports
- Function of G-Protein-Coupled Estrogen Receptor-1 in Reproductive System Tumors
- (2016) Hongyan Qian et al. Journal of Immunology Research
- Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry
- (2015) Maria E. Nilsson et al. ENDOCRINOLOGY
- Intracellular Distribution and Involvement of GPR30 in the Actions of E2 on C2C12 Cells
- (2015) Ana C. Ronda et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- What have we learned about GPER function in physiology and disease from knockout mice?
- (2015) Eric R. Prossnitz et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- GPER Mediates Activation of HIF1 /VEGF Signaling by Estrogens
- (2014) E. M. De Francesco et al. CANCER RESEARCH
- Estradiol and cognitive function: Past, present and future
- (2014) Victoria N. Luine HORMONES AND BEHAVIOR
- Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis
- (2014) Kathryn E. Davis et al. HORMONES AND BEHAVIOR
- Estrogen Signaling in Metabolic Inflammation
- (2014) Rosário Monteiro et al. MEDIATORS OF INFLAMMATION
- The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo
- (2014) W Wei et al. Cell Death & Disease
- G Protein-coupled Estrogen Receptor Protects from Atherosclerosis
- (2014) Matthias R. Meyer et al. Scientific Reports
- Resveratrol inhibits Kv2.2 currents through the estrogen receptor GPR30-mediated PKC pathway
- (2013) Wen-Hao Dong et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis
- (2013) Franck Mauvais-Jarvis et al. ENDOCRINE REVIEWS
- Post-synaptic Density-95 (PSD-95) Binding Capacity of G-protein-coupled Receptor 30 (GPR30), an Estrogen Receptor That Can Be Identified in Hippocampal Dendritic Spines
- (2013) Keith T. Akama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cross-talk between GPER and growth factor signaling
- (2013) Rosamaria Lappano et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Anatomical location and redistribution of G protein-coupled estrogen receptor-1 during the estrus cycle in mouse kidney and specific binding to estrogens but not aldosterone
- (2013) Shi-Bin Cheng et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells
- (2013) Adele Chimento et al. MOLECULAR NUTRITION & FOOD RESEARCH
- The key involvement of estrogen receptor β and G-protein-coupled receptor 30 in the neuroprotective action of daidzein
- (2013) M. Kajta et al. NEUROSCIENCE
- GPER-1 acts as a tumor suppressor in ovarian cancer
- (2013) Tanja Ignatov et al. Journal of Ovarian Research
- Importance of estrogen receptors in adipose tissue function
- (2013) Matthias Blüher Molecular Metabolism
- The G protein-coupled receptor GPR30 mediates the proliferative and invasive effects induced by hydroxytamoxifen in endometrial cancer cells
- (2012) Gui-Qiang Du et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Exploration of Global Gene Expression Changes During the Estrous Cycle in Equine Endometrium1
- (2012) Simone Gebhardt et al. BIOLOGY OF REPRODUCTION
- Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells
- (2012) R. Lappano et al. CURRENT CANCER DRUG TARGETS
- Minireview: G Protein-Coupled Estrogen Receptor-1, GPER-1: Its Mechanism of Action and Role in Female Reproductive Cancer, Renal and Vascular Physiology
- (2012) Edward J. Filardo et al. ENDOCRINOLOGY
- The G Protein–Coupled Receptor GPR30 Mediates the Nontranscriptional Effect of Estrogen on the Activation of PI3K/Akt Pathway in Endometrial Cancer Cells
- (2012) Xin Ge et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- GPER regulates endothelin-dependent vascular tone and intracellular calcium
- (2012) Matthias R. Meyer et al. LIFE SCIENCES
- GPR30, the Non-Classical Membrane G Protein Related Estrogen Receptor, Is Overexpressed in Human Seminoma and Promotes Seminoma Cell Proliferation
- (2012) Nicolas Chevalier et al. PLoS One
- G-Protein Coupled Receptor 30 (GPR30): A Novel Regulator of Endothelial Inflammation
- (2012) Subhadeep Chakrabarti et al. PLoS One
- The G-Protein-Coupled Estrogen Receptor (GPER) is Expressed in Normal Human Ovaries and is Upregulated in Ovarian Endometriosis and Pelvic Inflammatory Disease Involving the Ovary
- (2012) Sabine Heublein et al. Reproductive Sciences
- Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors
- (2011) M. R. Meyer et al. Acta Physiologica
- Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women
- (2011) Eija Pöllänen et al. AGING CELL
- Role of GPER/GPR30 in tumoral testicular germ cells proliferation
- (2011) Nicolas Chevalier et al. CANCER BIOLOGY & THERAPY
- GPR30 Activation Opposes Estrogen-Dependent Uterine Growth via Inhibition of Stromal ERK1/2 and Estrogen Receptor Alpha (ERα) Phosphorylation Signals
- (2011) Fei Gao et al. ENDOCRINOLOGY
- G-1-Activated Membrane Estrogen Receptors Mediate Increased Contractility of the Human Myometrium
- (2011) K. Maiti et al. ENDOCRINOLOGY
- Estrogen Receptor GPR30 Reduces Oxidative Stress and Proteinuria in the Salt-Sensitive Female mRen2.Lewis Rat
- (2011) Sarah H. Lindsey et al. HYPERTENSION
- Equol-Stimulated Mitochondrial Reactive Oxygen Species Activate Endothelial Nitric Oxide Synthase and Redox Signaling in Endothelial Cells
- (2011) David J. Rowlands et al. HYPERTENSION
- Bisphenol A promotes testicular seminoma cell proliferation through GPER/GPR30
- (2011) Nicolas Chevalier et al. INTERNATIONAL JOURNAL OF CANCER
- Down-modulation of the G-protein-coupled Estrogen Receptor, GPER, from the Cell Surface Occurs via atrans-Golgi-Proteasome Pathway
- (2011) Shi-Bin Cheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity
- (2011) Megan K. Dennis et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus
- (2011) Shi-Bin Cheng et al. STEROIDS
- Metabolic impact of sex hormones on obesity
- (2010) Lynda M. Brown et al. BRAIN RESEARCH
- Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest
- (2010) Q K Y Chan et al. CELL DEATH AND DIFFERENTIATION
- Estrogen Receptors: Therapies Targeted to Receptor Subtypes
- (2010) S Nilsson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Genistein Induces Pancreatic β-Cell Proliferation through Activation of Multiple Signaling Pathways and Prevents Insulin-Deficient Diabetes in Mice
- (2010) Zhuo Fu et al. ENDOCRINOLOGY
- Bisphenol A induces a rapid activation of Erk1/2 through GPR30 in human breast cancer cells
- (2010) S. Dong et al. ENVIRONMENTAL POLLUTION
- Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice
- (2010) Alexander Balhuizen et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- 17β-Estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ERα
- (2010) Adele Chimento et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Involvement of Estrogen Receptor Variant ER-α36, Not GPR30, in Nongenomic Estrogen Signaling
- (2010) Lianguo Kang et al. MOLECULAR ENDOCRINOLOGY
- G Protein-Coupled Estrogen Receptor 1/G Protein-Coupled Receptor 30 Localizes in the Plasma Membrane and Traffics Intracellularly on Cytokeratin Intermediate Filaments
- (2010) C. Sanden et al. MOLECULAR PHARMACOLOGY
- Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models
- (2010) S. Gingerich et al. NEUROSCIENCE
- Dilation of Epicardial Coronary Arteries by the G Protein-Coupled Estrogen Receptor Agonists G-1 and ICI 182,780
- (2010) Matthias R. Meyer et al. PHARMACOLOGY
- Acute Administration of Non-Classical Estrogen Receptor Agonists Attenuates Ischemia-Induced Hippocampal Neuron Loss in Middle-Aged Female Rats
- (2010) Diane Lebesgue et al. PLoS One
- Estrogen Regulates Estrogen Receptors and Antioxidant Gene Expression in Mouse Skeletal Muscle
- (2010) Kristen A. Baltgalvis et al. PLoS One
- Rapid, nongenomic estrogen actions protect pancreatic islet survival
- (2010) Suhuan Liu et al. Islets
- Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30
- (2009) Qingming Ding et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway
- (2009) Yin-Yan He et al. CANCER SCIENCE
- Estrogen Contributes to Gender Differences in Mouse Ventricular Repolarization
- (2009) Tomoaki Saito et al. CIRCULATION RESEARCH
- Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity
- (2009) Elvira Haas et al. CIRCULATION RESEARCH
- Discovery of Selective Probes and Antagonists for G Protein-Coupled Receptors FPR/FPRL1 and GPR30
- (2009) Jeffrey Arterburn et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Importance of Extranuclear Estrogen Receptor- and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival
- (2009) S. Liu et al. DIABETES
- G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator?
- (2009) Ellis R. Levin ENDOCRINOLOGY
- Chronic Treatment with the G Protein-Coupled Receptor 30 Agonist G-1 Decreases Blood Pressure in Ovariectomized mRen2.Lewis Rats
- (2009) Sarah Hoffmann Lindsey et al. ENDOCRINOLOGY
- Minireview: Estrogenic Protection of β-Cell Failure in Metabolic Diseases
- (2009) Suhuan Liu et al. ENDOCRINOLOGY
- Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues
- (2009) Georgina G J Hazell et al. JOURNAL OF ENDOCRINOLOGY
- Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia
- (2009) Siok L. Dun et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Membrane oestrogen receptor α signalling to cell functions
- (2009) Ellis R. Levin JOURNAL OF PHYSIOLOGY-LONDON
- Central effects of estradiol in the regulation of food intake, body weight, and adiposity
- (2009) L.M. Brown et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Non-genomic regulation of vascular cell function and growth by estrogen
- (2009) Matthias R. Meyer et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- In vivo effects of a GPR30 antagonist
- (2009) Megan K Dennis et al. Nature Chemical Biology
- Plasma membrane estrogen receptors
- (2009) Ellis R. Levin TRENDS IN ENDOCRINOLOGY AND METABOLISM
- GPR30/GPER1: searching for a role in estrogen physiology
- (2009) Björn Olde et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- GPR30 Does Not Mediate Estrogenic Responses in Reproductive Organs in Mice
- (2008) Christiane Otto et al. BIOLOGY OF REPRODUCTION
- The G Protein-Coupled Receptor GPR30 Inhibits Human Urothelial Cell Proliferation
- (2008) Jian Teng et al. ENDOCRINOLOGY
- G Protein-Coupled Receptor 30 Localizes to the Endoplasmic Reticulum and Is Not Activated by Estradiol
- (2008) Christiane Otto et al. ENDOCRINOLOGY
- The Novel Estrogen Receptor, G Protein-Coupled Receptor 30, Mediates the Proliferative Effects Induced by 17β-Estradiol on Mouse Spermatogonial GC-1 Cell Line
- (2008) Rosa Sirianni et al. ENDOCRINOLOGY
- Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice
- (2008) Jörg Isensee et al. ENDOCRINOLOGY
- Deletion of the G Protein-Coupled Receptor 30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-Stimulated Insulin Release in Female Mice
- (2008) Ulrika E. A. Mårtensson et al. ENDOCRINOLOGY
- Bisphenol A at Environmentally Relevant Doses Inhibits Adiponectin Release from Human Adipose Tissue Explants and Adipocytes
- (2008) Eric R. Hugo et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Retracted: G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells
- (2008) Lidia Albanito et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Estrogens and age-related memory decline in rodents: What have we learned and where do we go from here?
- (2008) Karyn M. Frick HORMONES AND BEHAVIOR
- Extra‐nuclear signaling of estrogen receptors
- (2008) Xiao‐Dong Fu et al. IUBMB LIFE
- The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone
- (2008) Terhi J Heino et al. JOURNAL OF ENDOCRINOLOGY
- Uncovering the mechanisms of estrogen effects on hippocampal function
- (2007) Joanna L. Spencer et al. FRONTIERS IN NEUROENDOCRINOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More