Identification of GL-V9 as a novel senolytic agent against senescent breast cancer cells

Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases

(2020) Shuling Song et al.   TRENDS IN BIOCHEMICAL SCIENCES

Therapy-Induced Senescence: An “Old” Friend Becomes the Enemy

(2020) Tareq Saleh et al.   Cancers

Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression

(2020) Dawei Yang et al.   ARCHIVES OF TOXICOLOGY

Breast Cancer Treatment

(2019) Adrienne G. Waks et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation

(2019) Brittany L. Baechler et al.   Autophagy

Enniatin B1-induced lysosomal membrane permeabilization in mouse embryonic fibroblasts

(2019) Carlos A. F. Oliveira et al.   Mycotoxin Research

Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven pro-tumorigenic senescent secretion

(2019) Huanmin Niu et al.   Acta Pharmaceutica Sinica B

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII

(2019) Yongjian Guo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting autophagy-related protein kinases for potential therapeutic purpose

(2019) Honggang Xiang et al.   Acta Pharmaceutica Sinica B

Strategies targeting cellular senescence

(2018) Yossi Ovadya et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective Anti-tumor Activity of wogonin targeting the Warburg Effect through stablizing p53

(2018) Yikai Zhao et al.   PHARMACOLOGICAL RESEARCH

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Senescence-associated reprogramming promotes cancer stemness

(2017) Maja Milanovic et al.   NATURE

Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

(2017) Viktor I. Korolchuk et al.   EBioMedicine

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse

(2016) Marco Demaria et al.   Cancer Discovery

Monitoring Lipid Peroxidation within Foam Cells by Lysosome-Targetable and Ratiometric Probe

(2015) Xinfu Zhang et al.   ANALYTICAL CHEMISTRY

Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage

(2015) Eduardo Cremonese Filippi-Chiela et al.   Autophagy

Autophagy, Metabolism, and Cancer

(2015) E. White et al.   CLINICAL CANCER RESEARCH

Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells

(2014) Yao-Huei Huang et al.   Autophagy

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress

(2012) Kamini Singh et al.   Autophagy

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Inhibitory effects of GL-V9 on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-2/9

(2011) Liwen Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

First-Line Trastuzumab Plus Epirubicin and Cyclophosphamide Therapy in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: Cardiac Safety and Efficacy Data From the Herceptin, Cyclophosphamide, and Epirubicin (HERCULES) Trial

(2010) Michael Untch et al.   JOURNAL OF CLINICAL ONCOLOGY