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Title
The relevance of mitochondrial morphology for human disease
Authors
Keywords
Mitochondriopathy, Cristae, OXPHOS, Parkinson’s disease, Alzheimer’s disease, Mitochondrial dynamics
Journal
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Volume 134, Issue -, Pages 105951
Publisher
Elsevier BV
Online
2021-02-21
DOI
10.1016/j.biocel.2021.105951
References
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Note: Only part of the references are listed.- Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner
- (2020) Arun Kumar Kondadi et al. EMBO REPORTS
- Shaping the mitochondrial inner membrane in health and disease
- (2020) L. Colina‐Tenorio et al. JOURNAL OF INTERNAL MEDICINE
- The cell biology of mitochondrial membrane dynamics
- (2020) Marta Giacomello et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca2+ efflux and Reactive Oxygen Species (ROS) homeostasis
- (2020) Marta Cherubini et al. NEUROBIOLOGY OF DISEASE
- MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation
- (2020) Till Stephan et al. EMBO JOURNAL
- MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes
- (2020) Ruchika Anand et al. Life Science Alliance
- MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites
- (2020) Parker S. Tirrell et al. JOURNAL OF CELL BIOLOGY
- Cristae Membrane Dynamics – A Paradigm Change
- (2020) Arun Kumar Kondadi et al. TRENDS IN CELL BIOLOGY
- MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics
- (2019) Delfina Larrea et al. HUMAN MOLECULAR GENETICS
- Calcium Deregulation and Mitochondrial Bioenergetics in GDAP1-Related CMT Disease
- (2019) Paloma González-Sánchez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy
- (2019) Nathalie Bernard-Marissal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinical-genetic features and peculiar muscle histopathology in infantile DNM1L -related mitochondrial epileptic encephalopathy
- (2019) Daniela Verrigni et al. HUMAN MUTATION
- Expanding and Underscoring the Hepato‐Encephalopathic Phenotype of QIL 1 / MIC 13
- (2019) Bianca E Russell et al. HEPATOLOGY
- A De Novo Dominant Negative Mutation in DNM1L Causes Sudden Onset Status Epilepticus with Subsequent Epileptic Encephalopathy
- (2019) S. Schmid et al. NEUROPEDIATRICS
- Mitochondrial dynamics and transport in Alzheimer's disease
- (2019) Padraig J. Flannery et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Impaired turnover of hyperfused mitochondria in severe axonal neuropathy due to a novel DRP1 mutation
- (2019) Fabiana Longo et al. HUMAN MOLECULAR GENETICS
- Novel and lethal case of cardiac involvement in DNM1L mitochondrial encephalopathy
- (2019) Daron Vandeleur et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Emerging concepts of mitochondrial dysfunction in Parkinson’s disease progression: Pathogenic and therapeutic implications
- (2019) Linchi Rani et al. MITOCHONDRION
- Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson’s disease
- (2019) Si-Tong Feng et al. PHARMACOLOGICAL RESEARCH
- Eight human OPA1 isoforms, long and short: What are they for?
- (2018) Valentina Del Dotto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- QIL1-dependent assembly of MICOS complex–lethal mutation in C19ORF70 resulting in liver disease and severe neurological retardation
- (2018) J. Gödiker et al. JOURNAL OF HUMAN GENETICS
- PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions
- (2018) Pei-I Tsai et al. MOLECULAR CELL
- α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton
- (2018) Dalila G. Ordonez et al. NEURON
- α-Synuclein and Tau: Mitochondrial Kill Switches
- (2018) Ulrike Pech et al. NEURON
- MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A
- (2018) Agostinho G. Rocha et al. SCIENCE
- Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease
- (2018) Sandra Franco-Iborra et al. Frontiers in Neuroscience
- Structural basis of mitochondrial receptor binding and constriction by DRP1
- (2018) Raghav Kalia et al. NATURE
- The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency
- (2018) Cinzia Bocca et al. Scientific Reports
- Loss of the mitochondrial i‐AAA protease YME1L leads to ocular dysfunction and spinal axonopathy
- (2018) Hans‐Georg Sprenger et al. EMBO Molecular Medicine
- Huntington's disease: a clinical review
- (2017) P. McColgan et al. EUROPEAN JOURNAL OF NEUROLOGY
- Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer’s Disease
- (2017) Lan Guo et al. JOURNAL OF ALZHEIMERS DISEASE
- A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis
- (2017) Juanjuan Zhang et al. Scientific Reports
- Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
- (2017) Simone Bido et al. Scientific Reports
- Mitochondria-associated membranes as hubs for neurodegeneration
- (2016) Michiel Krols et al. ACTA NEUROPATHOLOGICA
- A novel de novo dominant negative mutation inDNM1Limpairs mitochondrial fission and presents as childhood epileptic encephalopathy
- (2016) Jill A. Fahrner et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Postnatal microcephaly and pain insensitivity due to a de novo heterozygousDNM1Lmutation causing impaired mitochondrial fission and function
- (2016) Ruth Sheffer et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice
- (2016) Rui Zhang et al. BRAIN RESEARCH
- Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit
- (2016) Avraham Zeharia et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation
- (2016) Miguel Barrera et al. FEBS LETTERS
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- (2016) Alessia Nasca et al. HUMAN MUTATION
- Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission
- (2016) Laura D. Osellame et al. JOURNAL OF CELL SCIENCE
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- (2016) Thomas MacVicar et al. JOURNAL OF CELL SCIENCE
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- (2016) Shanmugam Manoharan et al. Oxidative Medicine and Cellular Longevity
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- (2016) Deborah Naon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Thanh N. Nguyen et al. TRENDS IN CELL BIOLOGY
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- (2016) Ruchika Anand et al. PLoS One
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- (2016) Liang Zhang et al. Scientific Reports
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- (2015) Sebastian Koob et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- DNM1L-related mitochondrial fission defect presenting as refractory epilepsy
- (2015) Jason R Vanstone et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Titration of mitochondrial fusion rescuesMff-deficient cardiomyopathy
- (2015) Hsiuchen Chen et al. JOURNAL OF CELL BIOLOGY
- Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygousOPA1mutation
- (2015) Ronen Spiegel et al. JOURNAL OF MEDICAL GENETICS
- MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives
- (2015) Giulia Stuppia et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
- (2015) Wenzhang Wang et al. NATURE MEDICINE
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
- (2015) Wei-ke Ji et al. eLife
- Huntington disease
- (2015) Gillian P. Bates et al. Nature Reviews Disease Primers
- The Gdap1 knockout mouse mechanistically links redox control to Charcot–Marie–Tooth disease
- (2014) Axel Niemann et al. BRAIN
- Early-onset Behr syndrome due to compound heterozygous mutations in OPA1
- (2014) Dominique Bonneau et al. BRAIN
- Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot–Marie–Tooth neuropathy
- (2014) Víctor López Del Amo et al. HUMAN MOLECULAR GENETICS
- Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
- (2014) Ruchika Anand et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial Dysfunctions in Neurodegenerative Diseases: Relevance to Alzheimer’s Disease
- (2014) Jana Hroudová et al. Biomed Research International
- Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
- (2013) Sara Cogliati et al. CELL
- Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission
- (2013) Nina Huber et al. EMBO REPORTS
- Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry
- (2013) David Pla-Martín et al. NEUROBIOLOGY OF DISEASE
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- Clinical Approach to Parkinson's Disease: Features, Diagnosis, and Principles of Management
- (2013) J. Massano et al. Cold Spring Harbor Perspectives in Medicine
- Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion
- (2012) Stefan Vielhaber et al. ACTA NEUROPATHOLOGICA
- Bioenergetic role of mitochondrial fusion and fission
- (2012) Benedikt Westermann BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Proteolytic control of mitochondrial function and morphogenesis
- (2012) Ruchika Anand et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
- (2012) X. Wang et al. HUMAN MOLECULAR GENETICS
- Plasma apolipoprotein O level increased in the patients with acute coronary syndrome
- (2012) Bi-lian Yu et al. JOURNAL OF LIPID RESEARCH
- Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes
- (2012) Hanan E Shamseldin et al. JOURNAL OF MEDICAL GENETICS
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis
- (2011) Karina von der Malsburg et al. DEVELOPMENTAL CELL
- The mitochondrial contact site complex, a determinant of mitochondrial architecture
- (2011) Max Harner et al. EMBO JOURNAL
- MiD49 and MiD51, new components of the mitochondrial fission machinery
- (2011) Catherine S Palmer et al. EMBO REPORTS
- Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential
- (2011) Rebecca Noack et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
- (2011) U. Shirendeb et al. HUMAN MOLECULAR GENETICS
- Charcot-Marie-Tooth-related GeneGDAP1Complements Cell Cycle Delay at G2/M Phase inSaccharomyces cerevisiae fis1Gene-defective Cells
- (2011) Anna Estela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
- (2011) Suzanne Hoppins et al. JOURNAL OF CELL BIOLOGY
- Mutations in INF2 Are a Major Cause of Autosomal Dominant Focal Segmental Glomerulosclerosis
- (2011) O. Boyer et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Early-onset severe neuromuscular phenotype associated with compound heterozygosity for OPA1 mutations
- (2011) Christian P. Schaaf et al. MOLECULAR GENETICS AND METABOLISM
- INF2Mutations in Charcot–Marie–Tooth Disease with Glomerulopathy
- (2011) Olivia Boyer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multi-system neurological disease is common in patients with OPA1 mutations
- (2010) P. Yu-Wai-Man et al. BRAIN
- Mitochondrial dysfunction and pathophysiology of Charcot–Marie–Tooth disease involving GDAP1 mutations
- (2010) Julien Cassereau et al. EXPERIMENTAL NEUROLOGY
- OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution
- (2010) G. Elachouri et al. GENOME RESEARCH
- Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
- (2010) J. Kim et al. HUMAN MOLECULAR GENETICS
- Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
- (2010) Hidenori Otera et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- Abnormal mitochondrial dynamics and neurodegenerative diseases
- (2009) Bo Su et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway
- (2009) G Liot et al. CELL DEATH AND DIFFERENTIATION
- Charcot–Marie–Tooth disease
- (2009) Kinga Szigeti et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis
- (2009) Elizabeth J Brown et al. NATURE GENETICS
- GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance
- (2009) Axel Niemann et al. NEUROBIOLOGY OF DISEASE
- Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor
- (2009) Konstanze M. Wagner et al. PLoS One
- Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients
- (2008) Xinglong Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Cristae formation—linking ultrastructure and function of mitochondria
- (2008) Michael Zick et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondrial fusion and function in Charcot–Marie–Tooth type 2A patient fibroblasts with mitofusin 2 mutations
- (2008) Elizabeth A. Amiott et al. EXPERIMENTAL NEUROLOGY
- Effects of overexpression of Huntingtin proteins on mitochondrial integrity
- (2008) Hongmin Wang et al. HUMAN MOLECULAR GENETICS
- Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease
- (2008) Laia Pedrola et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- Mutant huntingtin and mitochondrial dysfunction
- (2008) Ella Bossy-Wetzel et al. TRENDS IN NEUROSCIENCES
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