Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy

(2015) Manuela Barneo-Muñoz et al.   PLoS Genetics

The Gdap1 knockout mouse mechanistically links redox control to Charcot–Marie–Tooth disease

(2014) Axel Niemann et al.   BRAIN

Junctophilin-1 is a modifier gene of GDAP1-related Charcot–Marie–Tooth disease

(2014) David Pla-Martín et al.   HUMAN MOLECULAR GENETICS

Redox Regulation of Store-Operated Ca2+ Entry

(2013) Paula Nunes et al.   ANTIOXIDANTS & REDOX SIGNALING

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission

(2013) Nina Huber et al.   EMBO REPORTS

Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry

(2013) David Pla-Martín et al.   NEUROBIOLOGY OF DISEASE

SnapShot: Membrane Curvature Sensors and Generators

(2012) Hongying Shen et al.   CELL

The intracellular redox state is a core determinant of mitochondrial fusion

(2012) Timothy Shutt et al.   EMBO REPORTS

Mechanisms of Membrane Curvature Sensing

(2011) Bruno Antonny   Annual Review of Biochemistry

Glutathione transferases: a structural perspective

(2011) Aaron Oakley   DRUG METABOLISM REVIEWS

Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease

(2011) Haider Raza   FEBS Journal

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential

(2011) Rebecca Noack et al.   HUMAN MOLECULAR GENETICS

Mitofusin 2 Regulates STIM1 Migration from the Ca2+Store to the Plasma Membrane in Cells with Depolarized Mitochondria

(2011) Karthika Singaravelu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dominant GDAP1 mutations cause predominantly mild CMT phenotypes

(2011) M. Zimon et al.   NEUROLOGY

A locus-specific database for mutations in GDAP1 allows analysis of genotype-phenotype correlations in Charcot-Marie-Tooth diseases type 4A and 2K

(2011) Julien Cassereau et al.   Orphanet Journal of Rare Diseases

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Membrane curvature during peroxisome fission requires Pex11

(2010) Łukasz Opaliński et al.   EMBO JOURNAL

Glutathione S-transferase π localizes in mitochondria and protects against oxidative stress

(2009) Shinji Goto et al.   FREE RADICAL BIOLOGY AND MEDICINE

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance

(2009) Axel Niemann et al.   NEUROBIOLOGY OF DISEASE

Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor

(2009) Konstanze M. Wagner et al.   PLoS One