Cristae undergo continuous cycles of membrane remodelling in a MICOS ‐dependent manner

Expanding and Underscoring the Hepato‐Encephalopathic Phenotype of QIL 1 / MIC 13

(2019) Bianca E Russell et al.   HEPATOLOGY

A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria

(2019) Sylvie Callegari et al.   JOURNAL OF MOLECULAR BIOLOGY

Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria

(2019) Stefan Stoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A photostable fluorescent marker for the superresolution live imaging of the dynamic structure of the mitochondrial cristae

(2019) Chenguang Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

(2019) Dane M Wolf et al.   EMBO JOURNAL

Live-cell STED nanoscopy of mitochondrial cristae

(2019) Till Stephan et al.   Scientific Reports

Who and how in the regulation of mitochondrial cristae shape and function

(2018) R. Quintana-Cabrera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis

(2018) Wonchul Shin et al.   CELL

QIL1-dependent assembly of MICOS complex–lethal mutation in C19ORF70 resulting in liver disease and severe neurological retardation

(2018) J. Gödiker et al.   JOURNAL OF HUMAN GENETICS

PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions

(2018) Pei-I Tsai et al.   MOLECULAR CELL

Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy

(2018) Xiaoshuai Huang et al.   NATURE BIOTECHNOLOGY

Dynamic nanoscale morphology of the ER surveyed by STED microscopy

(2018) Lena K. Schroeder et al.   JOURNAL OF CELL BIOLOGY

The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology

(2017) Daryna Tarasenko et al.   JOURNAL OF CELL BIOLOGY

Mic10, a Core Subunit of the Mitochondrial Contact Site and Cristae Organizing System, Interacts with the Dimeric F 1 F o -ATP Synthase

(2017) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

(2017) Manuel Hessenberger et al.   Nature Communications

Classification and Segmentation of Nanoparticle Diffusion Trajectories in Cellular Micro Environments

(2017) Thorsten Wagner et al.   PLoS One

Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex

(2016) Martijn A. Huynen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit

(2016) Avraham Zeharia et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation

(2016) Miguel Barrera et al.   FEBS LETTERS

Disrupted in schizophrenia 1 (DISC1) is a constituent of the mammalian mitochondrial contact site and cristae organizing system (MICOS) complex, and is essential for oxidative phosphorylation

(2016) Estefanía Piñero-Martos et al.   HUMAN MOLECULAR GENETICS

MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

(2016) Mari J. Aaltonen et al.   JOURNAL OF CELL BIOLOGY

The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy

(2016) Amy E. Vincent et al.   Scientific Reports

Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control

(2016) Christina Glytsou et al.   Cell Reports

QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease

(2016) Virginia Guarani et al.   eLife

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells

(2016) Ruchika Anand et al.   PLoS One

The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions

(2015) Sebastian Koob et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mic10 Oligomerization Pinches off Mitochondrial Cristae

(2015) Dusanka Milenkovic et al.   Cell Metabolism

Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions

(2015) Mariam Barbot et al.   Cell Metabolism

Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System

(2015) Maria Bohnert et al.   Cell Metabolism

Ancient Homology of the Mitochondrial Contact Site and Cristae Organizing System Points to an Endosymbiotic Origin of Mitochondrial Cristae

(2015) Sergio A. Muñoz-Gómez et al.   CURRENT BIOLOGY

CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis

(2015) E. C. Genin et al.   EMBO Molecular Medicine

Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder

(2015) Alexander J Abrams et al.   NATURE GENETICS

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

(2015) Christian Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

(2015) Virginia Guarani et al.   eLife

Late onset spinal motor neuronopathy is caused by mutation inCHCHD10

(2014) Sini Penttilä et al.   ANNALS OF NEUROLOGY

Novel intracellular functions of apolipoproteins: the ApoO protein family as constituents of the Mitofilin/MINOS complex determines cristae morphology in mitochondria

(2014) Sebastian Koob et al.   BIOLOGICAL CHEMISTRY

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

(2014) Nikolaus Pfanner et al.   JOURNAL OF CELL BIOLOGY

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

(2014) Nadine Tarantino et al.   JOURNAL OF CELL BIOLOGY

Lateral pH gradient between OXPHOS complex IV and F0F1 ATP-synthase in folded mitochondrial membranes

(2014) Bettina Rieger et al.   Nature Communications

The connection between inner membrane topology and mitochondrial function

(2013) Carmen A. Mannella et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

(2013) Gražvydas Lukinavičius et al.   Nature Chemistry

APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria

(2013) Tobias A. Weber et al.   PLoS One

STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria

(2013) D. C. Jans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture

(2012) Ralf M. Zerbes et al.   BIOLOGICAL CHEMISTRY

Restricted diffusion of OXPHOS complexes in dynamic mitochondria delays their exchange between cristae and engenders a transitory mosaic distribution

(2012) Verena Wilkens et al.   JOURNAL OF CELL SCIENCE

Sam50 Functions in Mitochondrial Intermembrane Space Bridging and Biogenesis of Respiratory Complexes

(2012) C. Ott et al.   MOLECULAR AND CELLULAR BIOLOGY

The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria

(2012) Christian Körner et al.   MOLECULAR BIOLOGY OF THE CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Simplified Equation to Extract Diffusion Coefficients from Confocal FRAP Data

(2012) Minchul Kang et al.   TRAFFIC

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Dynamic Superresolution Imaging of Endogenous Proteins on Living Cells at Ultra-High Density

(2010) Gregory Giannone et al.   BIOPHYSICAL JOURNAL

The Micro-Architecture of Mitochondria at Active Zones: Electron Tomography Reveals Novel Anchoring Scaffolds and Cristae Structured for High-Rate Metabolism

(2010) G. A. Perkins et al.   JOURNAL OF NEUROSCIENCE

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Cristae formation—linking ultrastructure and function of mitochondria

(2008) Michael Zick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

An Engineered Protein Tag for Multiprotein Labeling in Living Cells

(2008) Arnaud Gautier et al.   CHEMISTRY & BIOLOGY

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL