Mitochondria: A critical hub for hepatic stellate cells activation during chronic liver diseases

Mechanisms of liver fibrosis and its role in liver cancer

(2020) Debanjan Dhar et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Novel targeted therapies for the management of liver fibrosis

(2020) Juan P. Trivella et al.   EXPERT OPINION ON EMERGING DRUGS

Recent development in acetyl-CoA carboxylase inhibitors and their potential as novel drugs

(2020) Xin Wu et al.   Future Medicinal Chemistry

Hepatic fibrosis: A convergent response to liver injury that is reversible

(2020) Shuang Wang et al.   JOURNAL OF HEPATOLOGY

Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation

(2020) Jamie Bates et al.   JOURNAL OF HEPATOLOGY

Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives

(2020) Natascha Roehlen et al.   Cells

Retinoids in health and disease: A role for hepatic stellate cells in affecting retinoid levels

(2020) Maya W. Haaker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells

(2019) Yilin Yu et al.   Cell Metabolism

Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases

(2019) Demine et al.   Cells

Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2

(2019) Dujing Ban et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

ATP-citrate lyase is an epigenetic regulator to promote obesity-related kidney injury

(2019) Yinyin Chen et al.   FASEB JOURNAL

Astaxanthin attenuates the increase in mitochondrial respiration during the activation of hepatic stellate cells

(2019) Minkyung Bae et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells

(2019) Hur et al.   Cells

Role of Mitophagy Regulation by ROS in Hepatic Stellate Cells during Acute Liver Failure

(2018) Zhen Tian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Stellate Cells in Tissue Repair, Inflammation, and Cancer

(2018) Mara H. Sherman   Annual Review of Cell and Developmental Biology

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells

(2018) Kuo Du et al.   GASTROENTEROLOGY

Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets

(2018) Devaraj Ezhilarasan et al.   Hepatobiliary & Pancreatic Diseases International

Mitochondria in non-alcoholic fatty liver disease

(2018) Inês C.M. Simões et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Elevated mitochondrial activity distinguishes fibrogenic hepatic stellate cells and sensitizes for selective inhibition by mitotropic doxorubicin

(2018) Priya Gajendiran et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase

(2018) Zhen Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective

(2018) Devaraj Ezhilarasan   Arab Journal of Gastroenterology

Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell

(2018) Wei-lun Ai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of canonical Hedgehog signaling pathway in liver

(2018) Lili Gao et al.   International Journal of Biological Sciences

Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response

(2018) Marie Bobowski-Gerard et al.   Cells

Human hepatic stellate cell isolation and characterization

(2017) Linshan Shang et al.   JOURNAL OF GASTROENTEROLOGY

Hepatic stellate cell activation and pro-fibrogenic signals

(2017) Chandrashekhar R. Gandhi   JOURNAL OF HEPATOLOGY

Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice

(2017) Nabanita Das et al.   JOURNAL OF PINEAL RESEARCH

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

AMPK: a novel target for treating hepatic fibrosis

(2017) Zhenxing Liang et al.   Oncotarget

Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling

(2017) Jieun Kim et al.   Scientific Reports

Curcumin inhibits aerobic glycolysis in hepatic stellate cells associated with activation of adenosine monophosphate-activated protein kinase

(2016) Naqi Lian et al.   IUBMB LIFE

Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury

(2016) Yong Yang et al.   TOXICOLOGY LETTERS

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

Mitochondrial uncouplers inhibit hepatic stellate cell activation

(2012) Eduardo L Guimarães et al.   BMC GASTROENTEROLOGY

Ameliorative effect of silibinin against N-nitrosodimethylamine-induced hepatic fibrosis in rats

(2012) Devaraj Ezhilarasan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

(2012) Yuping Chen et al.   GASTROENTEROLOGY

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

(2011) Erica Novo et al.   JOURNAL OF PATHOLOGY

Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes

(2010) Anna Maria Brunati et al.   FREE RADICAL RESEARCH

Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice

(2010) Subhadip Ghatak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Therapeutic targeting of the PDGF and TGF-β-signaling pathways in hepatic stellate cells by PTK787/ZK22258

(2009) Yuqing Liu et al.   LABORATORY INVESTIGATION

TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis

(2008) Kazuo Fujisawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS