Phage-Derived Antibacterials: Harnessing the Simplicity, Plasticity, and Diversity of Phages

The History and Promising Future of Phage Therapy in the Military Service

(2018) Daniel Gelman et al.   Journal of Trauma and Acute Care Surgery

T7 phage factor required for managing RpoS inEscherichia coli

(2018) Aline Tabib-Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Framing the Future with Bacteriophages in Agriculture

(2018) Antonet Svircev et al.   Viruses-Basel

A Pilin Region Affecting Host Range of the Pseudomonas aeruginosa RNA Phage, PP7

(2018) Eun Sook Kim et al.   Frontiers in Microbiology

The History and Promising Future of Phage Therapy in the Military Service

(2018) Daniel Gelman et al.   Journal of Trauma and Acute Care Surgery

Pseudomonas chlororaphis Produces Multiple R-Tailocin Particles That Broaden the Killing Spectrum and Contribute to Persistence in Rhizosphere Communities

(2018) Robert J. Dorosky et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Efficacy of chimeric ectolysin P128 in drug-resistant Staphylococcus aureus bacteraemia in mice

(2018) Shankaramurthy Channabasappa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion

(2018) Johan Seijsing et al.   Frontiers in Microbiology

A carrier state is established in Pseudomonas aeruginosa by phage LeviOr01, a newly isolated ssRNA levivirus

(2017) Christine Pourcel et al.   JOURNAL OF GENERAL VIROLOGY

Pseudomonas predators: understanding and exploiting phage–host interactions

(2017) Jeroen De Smet et al.   NATURE REVIEWS MICROBIOLOGY

A Novel Antimicrobial Endolysin, LysPA26, against Pseudomonas aeruginosa

(2017) Mingquan Guo et al.   Frontiers in Microbiology

Bacteriophages and Bacterial Plant Diseases

(2017) Colin Buttimer et al.   Frontiers in Microbiology

Phage Tail–Like Bacteriocins

(2017) Dean Scholl   Annual Review of Virology

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

(2016) Valerie Defraine et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetically Engineered Phages: a Review of Advances over the Last Decade

(2016) Diana P. Pires et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus

(2016) Xinghong Dai et al.   NATURE

Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ

(2016) Roman I Koning et al.   Nature Communications

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

(2016) An Van den Bossche et al.   eLife

Enhanced Antibacterial Activity of Acinetobacter baumannii Bacteriophage ØABP-01 Endolysin (LysABP-01) in Combination with Colistin

(2016) Rapee Thummeepak et al.   Frontiers in Microbiology

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae

(2015) R. Diez-Martinez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states

(2015) Peng Ge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity

(2015) Dana Gebhart et al.   mBio

Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states

(2015) Peng Ge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibacterial phage ORFans of Pseudomonas aeruginosa phage LUZ24 reveal a novel MvaT inhibiting protein

(2015) Jeroen Wagemans et al.   Frontiers in Microbiology

Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing

(2015) Hiroki Ando et al.   Cell Systems

Inhibition of Biofilm Formation by T7 Bacteriophages Producing Quorum-Quenching Enzymes

(2014) Ruoting Pei et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacteriophage ϕMAM1, a Viunalikevirus, Is a Broad-Host-Range, High-Efficiency Generalized Transducer That Infects Environmental and Clinical Isolates of the Enterobacterial Genera Serratia and Kluyvera

(2014) Miguel A. Matilla et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The antibiotic resistome: what's new?

(2014) Julie Ann Perry et al.   CURRENT OPINION IN MICROBIOLOGY

Systematic Identification of Hypothetical Bacteriophage Proteins Targeting Key Protein Complexes of Pseudomonas aeruginosa

(2014) An Van den Bossche et al.   JOURNAL OF PROTEOME RESEARCH

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

(2014) Robert J Citorik et al.   NATURE BIOTECHNOLOGY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly

(2014) I.-Y. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

Biofilm-degrading enzymes fromLysobacter gummosus

(2014) Anke Gökçen et al.   Virulence

Improving the Lethal Effect of Cpl-7, a Pneumococcal Phage Lysozyme with Broad Bactericidal Activity, by Inverting the Net Charge of Its Cell Wall-Binding Module

(2013) Roberto Díez-Martínez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Use of a bacteriophage cocktail to control Salmonella in food and the food industry

(2013) Denis Augusto Spricigo et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

(2013) Sheetal R. Modi et al.   NATURE

Gene product 0.4 increases bacteriophage T7 competitiveness by inhibiting host cell division

(2013) R. Kiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of  70 domain 1.1

(2013) B. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common virulence factors for Pseudomonas tolaasii pathogenesis in Agaricus and Arabidopsis

(2013) In-Young Chung et al.   RESEARCH IN MICROBIOLOGY

Understanding Bacteriophage Specificity in Natural Microbial Communities

(2013) Britt Koskella et al.   Viruses-Basel

Antibacterial Efficacy of Temperate Phage-Mediated Inhibition of Bacterial Group Motilities

(2012) In-Young Chung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

THE ORIGIN OF SPECIFICITY BY MEANS OF NATURAL SELECTION: EVOLVED AND NONHOST RESISTANCE IN HOST-PATHOGEN INTERACTIONS

(2012) Janis Antonovics et al.   EVOLUTION

OXA-48-like carbapenemases: the phantom menace

(2012) L. Poirel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

T4-Related Bacteriophage LIMEstone Isolates for the Control of Soft Rot on Potato Caused by ‘Dickeya solani’

(2012) Evelien M. Adriaenssens et al.   PLoS One

Genome Sequence of E. coli O104:H4 Leads to Rapid Development of a Targeted Antimicrobial Agent against This Emerging Pathogen

(2012) Dean Scholl et al.   PLoS One

A T3 and T7 Recombinant Phage Acquires Efficient Adsorption and a Broader Host Range

(2012) Tiao-Yin Lin et al.   PLoS One

Host RNA polymerase inhibitors encoded by ϕKMV-like phages of pseudomonas

(2012) Evgeny Klimuk et al.   VIROLOGY

The Staphylococci Phages Family: An Overview

(2012) Marie Deghorain et al.   Viruses-Basel

An Escherichia coli O157-Specific Engineered Pyocin Prevents and Ameliorates Infection by E. coli O157:H7 in an Animal Model of Diarrheal Disease

(2011) Jennifer M. Ritchie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Reversing Bacterial Resistance to Antibiotics by Phage-Mediated Delivery of Dominant Sensitive Genes

(2011) Rotem Edgar et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A novel bacteriophage Tail-Associated Muralytic Enzyme (TAME) from Phage K and its development into a potent antistaphylococcal protein

(2011) Vivek Paul et al.   BMC MICROBIOLOGY

Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection

(2011) Vivek Paul et al.   BMC MICROBIOLOGY

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

The phage-host arms race: Shaping the evolution of microbes

(2010) Adi Stern et al.   BIOESSAYS

Food applications of bacterial cell wall hydrolases

(2010) Lien Callewaert et al.   CURRENT OPINION IN BIOTECHNOLOGY

Phage Therapy in Clinical Practice: Treatment of Human Infections

(2010) Elizabeth Kutter et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Bacteriophages ofPseudomonas

(2010) Pieter-Jan Ceyssens et al.   Future Microbiology

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader

(2010) Sho T. Yano et al.   MOLECULAR MICROBIOLOGY

An Engineered R-Type Pyocin Is a Highly Specific and Sensitive Bactericidal Agent for the Food-Borne Pathogen Escherichia coli O157:H7

(2009) D. Scholl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Site-specific recombination of T2 phage using IP008 long tail fiber genes provides a targeted method for expanding host range while retaining lytic activity

(2009) Faezeh Mahichi et al.   FEMS MICROBIOLOGY LETTERS

Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy

(2009) T. K. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibacterial Efficacy of R-Type Pyocins towards Pseudomonas aeruginosa in a Murine Peritonitis Model

(2008) D. Scholl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Retargeting R-Type Pyocins To Generate Novel Bactericidal Protein Complexes

(2008) S. R. Williams et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Tail-associated structural protein gp61 ofStaphylococcus aureusphage φMR11 has bifunctional lytic activity

(2008) Mohammad Rashel et al.   FEMS MICROBIOLOGY LETTERS

Phage inactivation of foodborne pathogens on cooked and raw meat

(2007) T. Bigwood et al.   FOOD MICROBIOLOGY