Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats
Authors
Keywords
Spinal cord injury, Phosphorylated ERK1/2, Astrocyte activation, Inflammation, Aquaporin-4
Journal
BRAIN RESEARCH BULLETIN
Volume 170, Issue -, Pages 162-173
Publisher
Elsevier BV
Online
2021-02-15
DOI
10.1016/j.brainresbull.2021.02.014
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury
- (2020) Xiao-Qiang Su et al. BRAIN RESEARCH BULLETIN
- Harpagide inhibits neuronal apoptosis and promotes axonal regeneration after spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway
- (2019) Yuluo Rong et al. BRAIN RESEARCH BULLETIN
- Secukinumab attenuates reactive astrogliosis via IL‐17RA/(C/EBPβ)/SIRT1 pathway in a rat model of germinal matrix hemorrhage
- (2019) Sheng‐Peng Liu et al. CNS Neuroscience & Therapeutics
- TGN-020 alleviates edema and inhibits astrocyte activation and glial scar formation after spinal cord compression injury in rats
- (2019) Jian Li et al. LIFE SCIENCES
- Dystroglycan is involved in the activation of ERK pathway inducing the change of AQP4 expression in scratch-injured astrocytes
- (2019) Gaoli Zhang et al. BRAIN RESEARCH
- Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke
- (2018) Bogdan Catalin et al. CNS & Neurological Disorders-Drug Targets
- Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury
- (2018) Sajad Fakhri et al. BRAIN RESEARCH BULLETIN
- Blockade of Aquaporin 4 Inhibits Irradiation-Induced Pulmonary Inflammation and Modulates Macrophage Polarization in Mice
- (2018) Yuhui Li et al. INFLAMMATION
- Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury
- (2018) Liang Zhao et al. Molecular Pain
- Trehalose attenuates spinal cord injury through the regulation of oxidative stress, inflammation and GFAP expression in rats
- (2018) Mahdieh Nazari-Robati et al. JOURNAL OF SPINAL CORD MEDICINE
- Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways
- (2017) Ionica Pirici et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Overexpression of aquaporin 4 in articular chondrocytes exacerbates the severity of adjuvant-induced arthritis in rats: an in vivo and in vitro study
- (2017) Li Cai et al. Journal of Inflammation-London
- Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury
- (2016) Maja Radulovic et al. NEUROBIOLOGY OF DISEASE
- PCBP2 Modulates Neural Apoptosis and Astrocyte Proliferation After Spinal Cord Injury
- (2016) Xingxing Mao et al. NEUROCHEMICAL RESEARCH
- Mdivi-1 Inhibits Astrocyte Activation and Astroglial Scar Formation and Enhances Axonal Regeneration after Spinal Cord Injury in Rats
- (2016) Gang Li et al. Frontiers in Cellular Neuroscience
- Anti-edema effect of melatonin on spinal cord injury in rats
- (2015) Xinwei Liu et al. BIOMEDICAL PAPERS-OLOMOUC
- An efficient device to experimentally model compression injury of mammalian spinal cord
- (2015) Alexander E. Ropper et al. EXPERIMENTAL NEUROLOGY
- Ischemic Postconditioning Alleviates Brain Edema After Focal Cerebral Ischemia Reperfusion in Rats Through Down-Regulation of Aquaporin-4
- (2015) Dong Han et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury
- (2015) Yona Goldshmit et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway
- (2015) Yidan Chen et al. Neuroscience Bulletin
- Curcumin improves the recovery of motor function and reduces spinal cord edema in a rat acute spinal cord injury model by inhibiting the JAK/STAT signaling pathway
- (2014) Jianing Zu et al. ACTA HISTOCHEMICA
- Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats
- (2013) Rui Ge et al. BRAIN RESEARCH
- The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate
- (2013) B B Lee et al. SPINAL CORD
- MEK inhibition reduces glial scar formation and promotes the recovery of sensorimotor function in rats following spinal cord injury
- (2013) BIN LIN et al. Experimental and Therapeutic Medicine
- The glial scar in spinal cord injury and repair
- (2013) Yi-Min Yuan et al. Neuroscience Bulletin
- Inhibition of ROS-induced p38MAPK and ERK activation in microglia by acupuncture relieves neuropathic pain after spinal cord injury in rats
- (2012) Doo C. Choi et al. EXPERIMENTAL NEUROLOGY
- Aquaporin 4: a player in cerebral edema and neuroinflammation
- (2012) Andrew M Fukuda et al. Journal of Neuroinflammation
- Protective effects of erythropoietin on astrocytic swelling after oxygen–glucose deprivation and reoxygenation: Mediation through AQP4 expression and MAPK pathway
- (2012) Zhaohua Tang et al. NEUROPHARMACOLOGY
- ERK1/2 MAP kinases: Structure, function, and regulation
- (2012) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Aquaporins in Clinical Medicine
- (2011) A.S. Verkman Annual Review of Medicine
- Aquaporin-4 Expression in Cultured Astrocytes after Fluid Percussion Injury
- (2011) Kakulavarapu V. Rama Rao et al. JOURNAL OF NEUROTRAUMA
- Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes
- (2011) S. R. Hinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Triptolide promotes spinal cord repair by inhibiting astrogliosis and inflammation
- (2010) Zhida Su et al. GLIA
- Aquaporin-4 in manganese-treated cultured astrocytes
- (2010) Kakulavarapu V. Rama Rao et al. GLIA
- Intrathecal pathogenic antiâaquaporin-4 antibodies in early neuromyelitis optica
- (2009) Jeffrey L. Bennett et al. ANNALS OF NEUROLOGY
- Tamoxifen attenuates inflammatory-mediated damage and improves functional outcome after spinal cord injury in rats
- (2009) Dai-Shi Tian et al. JOURNAL OF NEUROCHEMISTRY
- Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice
- (2008) S. Saadoun et al. BRAIN
- Evidence for the Role of Mitogen-Activated Protein Kinase Signaling Pathways in the Development of Spinal Cord Injury
- (2008) T. Genovese et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Upregulation of water channel aquaporin-4 in experimental autoimmune encephalomyeritis
- (2008) Katsuichi Miyamoto et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started