Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding

Melting of Hemoglobin in Native Solutions as measured by IMS-MS

(2020) Daniel W. Woodall et al.   ANALYTICAL CHEMISTRY

Structural Analysis of the Effect of a Dual-FLAG Tag on Transthyretin

(2020) Mehdi Shirzadeh et al.   BIOCHEMISTRY

Molecular mechanism of ISC iron-sulfur cluster biogenesis revealed by high-resolution native mass spectrometry

(2020) Cheng-Wei Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studying biomolecular folding and binding using temperature-jump mass spectrometry

(2020) Adrien Marchand et al.   Nature Communications

First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes

(2020) Jacob W. McCabe et al.   ANALYTICAL CHEMISTRY

Discovery of Potent Charge-Reducing Molecules for Native Ion Mobility Mass Spectrometry Studies

(2020) Jixing Lyu et al.   ANALYTICAL CHEMISTRY

Understanding the Thermal Denaturation of Myoglobin with IMS-MS: Evidence for Multiple Stable Structures and Trapped Pre-equilibrium States

(2020) Daniel W. Woodall et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY‐MASS SPECTROMETRY

(2020) Jacob W. McCabe et al.   MASS SPECTROMETRY REVIEWS

Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements

(2020) Shannon A. Raab et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of native MS capabilities on an extended mass range Q-TOF MS

(2020) Christopher S. Mallis et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond

(2019) Daniel W. Woodall et al.   ANALYTICAL CHEMISTRY

A Cyclic Ion Mobility – Mass Spectrometry System

(2019) Kevin Giles et al.   ANALYTICAL CHEMISTRY

The role of circular dichroism spectroscopy in the era of integrative structural biology

(2019) BA Wallace   CURRENT OPINION IN STRUCTURAL BIOLOGY

Substance P in the Gas Phase: Conformational Changes and Dissociations Induced by Collisional Activation in a Drift Tube

(2019) Christopher R. Conant et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Characterizing Thermal Transitions of IgG with Mass Spectrometry

(2019) Christopher J. Brown et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Native IM-Orbitrap MS: Resolving what was hidden

(2019) Michael L. Poltash et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism

(2019) Nicholas G. Fox et al.   Nature Communications

Solution thermochemistry of concanavalin A tetramer conformers measured by variable-temperature ESI-IMS-MS

(2019) Tarick J. El-Baba et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Mechanism of activation of the human cysteine desulfurase complex by frataxin

(2019) Shachin Patra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melting proteins confined in nanodroplets with 10.6 μm light provides clues about early steps of denaturation

(2018) Tarick J. El-Baba et al.   CHEMICAL COMMUNICATIONS

Parsimonious Charge Deconvolution for Native Mass Spectrometry

(2018) Marshall Bern et al.   JOURNAL OF PROTEOME RESEARCH

Conformationally regulated peptide bond cleavage in bradykinin

(2018) Daniel R. Fuller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer

(2018) Michael L. Poltash et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry

(2018) Michael L. Poltash et al.   ANALYTICAL CHEMISTRY

Melting Proteins: Evidence for Multiple Stable Structures upon Thermal Denaturation of Native Ubiquitin from Ion Mobility Spectrometry-Mass Spectrometry Measurements

(2017) Tarick J. El-Baba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

GroEL actively stimulates folding of the endogenous substrate protein PepQ

(2017) Jeremy Weaver et al.   Nature Communications

Long-Lived Intermediates in a Cooperative Two-State Folding Transition

(2016) Tarick J. El-Baba et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Determining Membrane Protein–Lipid Binding Thermodynamics Using Native Mass Spectrometry

(2016) Xiao Cong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cis→Trans Isomerization of Pro7 in Oxytocin Regulates Zn2+ Binding

(2016) Daniel R. Fuller et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

“Wet” Versus “Dry” Folding of Polyproline

(2016) Liuqing Shi et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

Cold Denaturation Unveiled: Molecular Mechanism of the Asymmetric Unfolding of Yeast Frataxin

(2015) Domenico Sanfelice et al.   CHEMPHYSCHEM

Configurationally-Coupled Protonation of Polyproline-7

(2015) Liuqing Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

(2014) Jennifer Bridwell-Rabb et al.   BIOCHEMISTRY

Characterizing Intermediates Along the Transition from Polyproline I to Polyproline II Using Ion Mobility Spectrometry-Mass Spectrometry

(2014) Liuqing Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The kinetics of folding of frataxin

(2014) Daniela Bonetti et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Frataxin: a protein in search for a function

(2013) Annalisa Pastore et al.   JOURNAL OF NEUROCHEMISTRY

Significance, P values and t-tests

(2013) Martin Krzywinski et al.   NATURE METHODS

Levinthal’s question revisited, and answered

(2012) Arieh Ben-Naim   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Conformation Types of Ubiquitin [M+8H]8+ Ions from Water:Methanol Solutions: Evidence for the N and A States in Aqueous Solution

(2012) Huilin Shi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Human Frataxin Is an Allosteric Switch That Activates the Fe−S Cluster Biosynthetic Complex

(2010) Chi-Lin Tsai et al.   BIOCHEMISTRY

Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly

(2010) Filippo Prischi et al.   Nature Communications

The N-terminus of mature human frataxin is intrinsically unfolded

(2009) Filippo Prischi et al.   FEBS Journal

Assembly reflects evolution of protein complexes

(2008) Emmanuel D. Levy et al.   NATURE

Ion mobility–mass spectrometry analysis of large protein complexes

(2008) Brandon T Ruotolo et al.   Nature Protocols