GroEL actively stimulates folding of the endogenous substrate protein PepQ

Allosteric Mechanisms in Chaperonin Machines

(2016) Ranit Gruber et al.   CHEMICAL REVIEWS

Chaperonin GroEL–GroES Functions as both Alternating and Non-Alternating Engines

(2016) Daisuke Yamamoto et al.   JOURNAL OF MOLECULAR BIOLOGY

The GroEL–GroES Chaperonin Machine: A Nano-Cage for Protein Folding

(2016) Manajit Hayer-Hartl et al.   TRENDS IN BIOCHEMICAL SCIENCES

Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system

(2015) Andrew J. Ambrose et al.   FEBS LETTERS

Chaperonin-Assisted Protein Folding: Relative Population of Asymmetric and Symmetric GroEL:GroES Complexes

(2015) Shubhasis Haldar et al.   JOURNAL OF MOLECULAR BIOLOGY

Intrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR

(2015) David S. Libich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

The Dynamic Conformational Cycle of the Group I Chaperonin C-Termini Revealed via Molecular Dynamics Simulation

(2015) Kevin M. Dalton et al.   PLoS One

GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding

(2014) Florian Georgescauld et al.   CELL

The C-terminal Tails of the Bacterial Chaperonin GroEL Stimulate Protein Folding by Directly Altering the Conformation of a Substrate Protein

(2014) Jeremy Weaver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Substrate Selectivity of E. coli Prolidase

(2014) Jeremy Weaver et al.   PLoS One

Formation and structures of GroEL:GroES2 chaperonin footballs, the protein-folding functional form

(2014) X. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein

(2013) Dong-Hua Chen et al.   CELL

Repetitive Protein Unfolding by thetransRing of the GroEL-GroES Chaperonin Complex Stimulates Folding

(2013) Zong Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Fluorescence Correlation Spectroscopy: An Efficient Tool for Measuring Size, Size-Distribution and Polydispersity of Microemulsion Droplets in Solution

(2011) Nibedita Pal et al.   ANALYTICAL CHEMISTRY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Chaperonins: two rings for folding

(2011) Hugo Yébenes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chaperonin-Catalyzed Rescue of Kinetically Trapped States in Protein Folding

(2010) Kausik Chakraborty et al.   CELL

A systematic survey of in vivo obligate chaperonin-dependent substrates

(2010) Kei Fujiwara et al.   EMBO JOURNAL

Coupled chaperone action in folding and assembly of hexadecameric Rubisco

(2010) Cuimin Liu et al.   NATURE

Conservation among HSP60 sequences in relation to structure, function, and evolution

(2010) Luciano Brocchieri et al.   PROTEIN SCIENCE

Reconciling theories of chaperonin accelerated folding with experimental evidence

(2009) Andrew I. Jewett et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The GroEL/GroES cis cavity as a passive anti-aggregation device

(2009) Arthur L. Horwich et al.   FEBS LETTERS

Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding

(2009) Arthur L. Horwich et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Monitoring Protein Conformation along the Pathway of Chaperonin-Assisted Folding

(2008) Shruti Sharma et al.   CELL

Triggering Protein Folding within the GroEL-GroES Complex

(2008) Damian Madan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrophilic Residues526KNDAAD531in the Flexible C-terminal Region of the Chaperonin GroEL Are Critical for Substrate Protein Folding within the Central Cavity

(2008) Kodai Machida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GroEL stimulates protein folding through forced unfolding

(2008) Zong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Setting the chaperonin timer: A two-stroke, two-speed, protein machine

(2008) J. P. Grason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Setting the chaperonin timer: The effects of K+ and substrate protein on ATP hydrolysis

(2008) J. P. Grason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperonin chamber accelerates protein folding through passive action of preventing aggregation

(2008) A. C. Apetri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational resources for cryo-electron tomography in Bsoft

(2007) J. Bernard Heymann et al.   JOURNAL OF STRUCTURAL BIOLOGY