Dual-Mode FEN1 Activity Detection Based on Nt.BstNBI-Induced Tandem Signal Amplification

Fluorometric detection of cancer marker FEN1 based on double-flapped dumbbell DNA nanoprobe functionalized with silver nanoclusters

(2021) Bingzhi Li et al.   ANALYTICA CHIMICA ACTA

Signal-Amplified Detection of the Tumor Biomarker FEN1 Based on Cleavage-Induced Ligation of a Dumbbell DNA Probe and Rolling Circle Amplification

(2021) Bingzhi Li et al.   ANALYTICAL CHEMISTRY

Fluorescent Assay of FEN1 Activity with Nicking Enzyme-Assisted Signal Amplification Based on ZIF-8 for Imaging in Living Cells

(2021) Yunfei Tang et al.   ANALYTICAL CHEMISTRY

Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

(2020) Yingying Zhang et al.   DISEASE MARKERS

Electrochemical Sensing of Exosomal MicroRNA Based on Hybridization Chain Reaction Signal Amplification with Reduced False-Positive Signals

(2020) Qunqun Guo et al.   ANALYTICAL CHEMISTRY

Aptamer-Cholesterol-Mediated Proximity Ligation Assay for Accurate Identification of Exosomes

(2020) Xianxian Zhao et al.   ANALYTICAL CHEMISTRY

Construction of a Quencher-Free Cascade Amplification System for Highly Specific and Sensitive Detection of Serum Circulating miRNAs

(2020) Li-juan Wang et al.   ANALYTICAL CHEMISTRY

Dumbbell Hybridization Chain Reaction Based Electrochemical Biosensor for Ultrasensitive Detection of Exosomal miRNA

(2020) Peng Miao et al.   ANALYTICAL CHEMISTRY

FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination

(2020) Elaine Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flap endonuclease 1 (FEN1) as a novel diagnostic and prognostic biomarker for gastric cancer

(2020) Enfa Zhao et al.   Clinics and Research in Hepatology and Gastroenterology

Cascade Transcription Amplification of RNA aptamer (RACTA) for Ultrasensitive MicroRNA Detection

(2019) Mengxi Zhou et al.   ANALYTICAL CHEMISTRY

MicroRNA-140 impedes DNA repair by targeting FEN1 and enhances chemotherapeutic response in breast cancer

(2019) Xiao Lu et al.   ONCOGENE

FEN1 inhibitor increases sensitivity of radiotherapy in cervical cancer cells

(2019) Jin‐Li Li et al.   Cancer Medicine

Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells

(2018) Lingfeng He et al.   DNA REPAIR

A label-free and enzyme-free platform with a visible output for constructing versatile logic gates using caged G-quadruplex as the signal transducer

(2018) Junhua Chen et al.   Chemical Science

Sensitive multicolor visual detection of telomerase activity based on catalytic hairpin assembly and etching of Au nanorods

(2018) Danni Wang et al.   BIOSENSORS & BIOELECTRONICS

Freezing-directed Stretching and Alignment of DNA Oligonucleotides

(2018) Biwu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems

(2018) Hao Zhang et al.   NANO LETTERS

Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

(2016) Lingfeng He et al.   EBioMedicine

QM/MM MD Simulations on the Enzymatic Pathway of the Human Flap Endonuclease (hFEN1) Elucidating Common Cleavage Pathways to RNase H Enzymes

(2015) Jacopo Sgrignani et al.   ACS Catalysis

Colorimetric Detection of Copper(II) Ion Using Click Chemistry and Hemin/G-Quadruplex Horseradish Peroxidase-Mimicking DNAzyme

(2014) Chenchen Ge et al.   ANALYTICAL CHEMISTRY

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

(2014) KEJIA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

(2014) Tarek M.A. Abdel-Fatah et al.   Molecular Oncology

Flap Endonuclease 1

(2013) Lata Balakrishnan et al.   Annual Review of Biochemistry

Ultrasensitive Detection of microRNAs by Exponential Isothermal Amplification

(2010) Hongxia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNAzyme-Like Activity of Hemin-Telomeric G-Quadruplexes for the Optical Analysis of Telomerase and its Inhibitors

(2010) Ronit Freeman et al.   CHEMBIOCHEM

Functional regulation of FEN1 nuclease and its link to cancer

(2010) L. Zheng et al.   NUCLEIC ACIDS RESEARCH

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing

(2009) K. J. McManus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA