Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

(2018) Keqiang Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells

(2018) Keiichiro Sakuma et al.   CANCER SCIENCE

Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells

(2018) Lingfeng He et al.   DNA REPAIR

New trials and results in systemic treatment of HCC

(2018) María Reig et al.   JOURNAL OF HEPATOLOGY

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2018) Peter R. Galle et al.   JOURNAL OF HEPATOLOGY

Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner

(2018) Jordan R Becker et al.   NUCLEIC ACIDS RESEARCH

Curcumin increases breast cancer cell sensitivity to cisplatin by decreasing FEN1 expression

(2018) Jiao Zou et al.   Oncotarget

Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes

(2018) Junhua Zhao et al.   Cell Reports

HBV infection and HCC: the ‘dangerous liaisons’

(2017) Antonio Bertoletti et al.   GUT

Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening

(2017) Amit Laxmikant Deshmukh et al.   Molecular BioSystems

FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer

(2017) Lingfeng He et al.   Molecular Oncology

Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

(2016) Lingfeng He et al.   EBioMedicine

Variants and haplotypes in Flap endonuclease 1 and risk of gallbladder cancer and gallstones: a population-based study in China

(2015) Xingyuan Jiao et al.   Scientific Reports

The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma

(2015) Jau-Chung Hwang et al.   PLoS One

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

(2014) KEJIA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

(2014) Tarek M.A. Abdel-Fatah et al.   Molecular Oncology

ANEIL1single nucleotide polymorphism (rs4462560) predicts the risk of radiation-induced toxicities in esophageal cancer patients treated with definitive radiotherapy

(2013) Yun Chen et al.   CANCER

Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population

(2013) Wen-Qing Li et al.   CARCINOGENESIS

Functional FEN1 genetic variants and haplotypes are associated with glioma risk

(2012) Yi-Dong Chen et al.   JOURNAL OF NEURO-ONCOLOGY

Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer

(2011) L. Liu et al.   CARCINOGENESIS

Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer

(2011) A Urbanucci et al.   ONCOGENE