Controlled release of MSC-derived small extracellular vesicles by an injectable Diels-Alder crosslinked hyaluronic acid/PEG hydrogel for osteoarthritis improvement

Therapeutic Use of Mesenchymal Stem Cell-Derived Exosomes: From Basic Science to Clinics

(2020) Carl Randall Harrell et al.   Pharmaceutics

Mesenchymal Stem Cell‐Derived Exosomes for Effective Cartilage Tissue Repair and Treatment of Osteoarthritis

(2020) Young Guk Kim et al.   Biotechnology Journal

Biomaterial strategies for improved intra‐articular drug delivery

(2020) Lina María Mancipe Castro et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke

(2020) Yuguo Xia et al.   Stem Cell Research & Therapy

Intraarticular Injection of Infliximab-Loaded Thermosensitive Hydrogel Alleviates Pain and Protects Cartilage in Rheumatoid Arthritis

(2020) Weiying Chen et al.   Journal of Pain Research

In vitro toxicity assessment of crosslinking agents used in hyaluronic acid dermal filler

(2020) Chang Hee Jeong et al.   TOXICOLOGY IN VITRO

Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration

(2019) Jacob Ren Jie Chew et al.   Acta Biomaterialia

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

(2019) Shannon Brown et al.   Acta Biomaterialia

MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis

(2019) Shipin Zhang et al.   BIOMATERIALS

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis

(2019) Jiangyi Wu et al.   BIOMATERIALS

Functionalization of Novel Theranostic Hydrogels with Kartogenin-Grafted USPIO Nanoparticles To Enhance Cartilage Regeneration

(2019) Wei Yang et al.   ACS Applied Materials & Interfaces

Concise Review: Mesenchymal Stromal Cell‐Derived Extracellular Vesicles for Regenerative Therapy and Immune Modulation: Progress and Challenges Toward Clinical Application

(2019) David S. Allan et al.   Stem Cells Translational Medicine

Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry

(2019) Ye Tian et al.   Journal of Extracellular Vesicles

Osteoarthritis

(2019) Benjamin Abramoff et al.   MEDICAL CLINICS OF NORTH AMERICA

Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry

(2018) Ye Tian et al.   ACS Nano

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity

(2018) Shipin Zhang et al.   BIOMATERIALS

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration

(2017) Xiaolin Liu et al.   Nanoscale

The role of metabolism in the pathogenesis of osteoarthritis

(2017) Ali Mobasheri et al.   Nature Reviews Rheumatology

Cartilage-targeting drug delivery: can electrostatic interactions help?

(2017) Ambika G. Bajpayee et al.   Nature Reviews Rheumatology

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

(2017) Yu Zhu et al.   Stem Cell Research & Therapy

Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice

(2016) Julie Pradal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ageing and the pathogenesis of osteoarthritis

(2016) Richard F. Loeser et al.   Nature Reviews Rheumatology

Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration

(2016) S. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Designing hydrogels for controlled drug delivery

(2016) Jianyu Li et al.   Nature Reviews Materials

Sustained intra-articular release of celecoxib from in situ forming gels made of acetyl-capped PCLA-PEG-PCLA triblock copolymers in horses

(2015) Audrey Petit et al.   BIOMATERIALS

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

(2015) Jieyuan Zhang et al.   Journal of Translational Medicine

Diels–Alder Hydrogels for Controlled Antibody Release: Correlation between Mesh Size and Release Rate

(2015) Susanne Kirchhof et al.   MOLECULAR PHARMACEUTICS

Injectable hydrogels based on poly(ethylene glycol) and derivatives as functional biomaterials

(2015) Emilia Bakaic et al.   RSC Advances

Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice

(2015) Guo-wen Hu et al.   Stem Cell Research & Therapy

Biodegradable and injectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for postoperative adhesion prevention

(2014) Ling Li et al.   BIOMATERIALS

Comparison of Piroxicam Pharmacokinetics and Anti-Inflammatory Effect in Rats after Intra-Articular and Intramuscular Administration

(2014) Chan Woong Park et al.   Biomolecules & Therapeutics

A systematic analysis of DMTMM vs EDC/NHS for ligation of amines to Hyaluronan in water

(2014) Matteo D’Este et al.   CARBOHYDRATE POLYMERS

Pharmacological effects of novel cross-linked hyaluronate, Gel-200, in experimental animal models of osteoarthritis and human cell lines

(2014) K. Yoshioka et al.   OSTEOARTHRITIS AND CARTILAGE

Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment

(2012) Wei Seong Toh et al.   BIOMATERIALS

Hydrogels for Protein Delivery

(2012) Tina Vermonden et al.   CHEMICAL REVIEWS

Unlike Bone, Cartilage Regeneration Remains Elusive

(2012) D. J. Huey et al.   SCIENCE

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Diels−Alder Click Cross-Linked Hyaluronic Acid Hydrogels for Tissue Engineering

(2011) Chelsea M. Nimmo et al.   BIOMACROMOLECULES

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Injectable thermosensitive hydrogels for intra-articular delivery of methotrexate

(2011) Bolong Miao et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Direct Synthesis of Biodegradable Polysaccharide Derivative Hydrogels Through Aqueous Diels-Alder Chemistry

(2011) Huaping Tan et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Generation of Human Induced Pluripotent Stem Cells from Umbilical Cord Matrix and Amniotic Membrane Mesenchymal Cells

(2010) Jinglei Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

Intra-articular drug delivery: The challenge to extend drug residence time within the joint

(2010) Scott H.R. Edwards   VETERINARY JOURNAL

PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine

(2008) Chien-Chi Lin et al.   PHARMACEUTICAL RESEARCH