Co-Administration of Gagam-Sipjeondaebo-Tang and Ibuprofen Alleviates the Inflammatory Response in MPTP-Induced Parkinson’s Disease Mouse Model and RAW264.7 Macrophages

Significant roles of neuroinflammation in Parkinson’s disease: therapeutic targets for PD prevention

(2019) Yujeong Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Juzentaihoto Suppresses Muscle Atrophy in Streptozotocin-Induced Diabetic Mice

(2019) Tomoaki Ishida et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons

(2019) Goutham K. Ganjam et al.   Cell Death & Disease

Uncaria rhynchophylla Ameliorates Parkinson’s Disease by Inhibiting HSP90 Expression: Insights from Quantitative Proteomics

(2018) Yu-Long Lan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets

(2018) Nese Unver et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Demethoxycurcumin, a natural derivative of curcumin abrogates rotenone-induced dopamine depletion and motor deficits by its antioxidative and anti-inflammatory properties in Parkinsonian rats

(2018) Srinivasagam Rajasankar et al.   Pharmacognosy Magazine

Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson’s Disease

(2018) Suresh B. Rangasamy et al.   Journal of Neuroimmune Pharmacology

Neuroprotective Effects of Gagam-Sipjeondaebo-Tang, a Novel Herbal Formula, against MPTP-Induced Parkinsonian Mice and MPP+-Induced Cell Death in SH-SY5Y Cells

(2018) Jade Heejae Ko et al.   Evidence-based Complementary and Alternative Medicine

Curative Anti-Inflammatory Properties of Chinese Optimized Yinxieling Formula in Models of Parkinson’s Disease

(2018) RenRong Wei et al.   Evidence-based Complementary and Alternative Medicine

Magnesium isoglycyrrhizinate suppresses LPS-induced inflammation and oxidative stress through inhibiting NF-κB and MAPK pathways in RAW264.7 cells

(2018) Chunfeng Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Essential Medicinal Chemistry of Curcumin

(2017) Kathryn M. Nelson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Deceptive curcumin offers cautionary tale for chemists

(2017) Monya Baker   NATURE

The role of interleukin-6 signaling in nervous tissue

(2016) Michelle Rothaug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway

(2016) Tao Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Evaluation of Models of Parkinson's Disease

(2016) Shail A. Jagmag et al.   Frontiers in Neuroscience

α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease

(2015) Byung-Wook Kim et al.   NEUROPHARMACOLOGY

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model

(2014) Ah-Reum Doo et al.   BMC Complementary and Alternative Medicine

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

(2014) Javier Sanchez-Padilla et al.   NATURE NEUROSCIENCE

Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

(2014) Augusta Pisanu et al.   NEUROBIOLOGY OF DISEASE

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Fermentation Improves Anti-Inflammatory Effect of Sipjeondaebotang on LPS-Stimulated RAW 264.7 Cells

(2012) You-Chang Oh et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Heme oxygenase-1-mediated reactive oxygen species reduction is involved in the inhibitory effect of curcumin on lipopolysaccharide-induced monocyte chemoattractant protein-1 production in RAW264.7 macrophages

(2012) YI ZHONG et al.   Molecular Medicine Reports

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Simultaneous determination of eight marker compounds in the traditional herbal medicine, sipjundaebo-tang by HPLC-DAD

(2011) Hye Jin Yang et al.   ARCHIVES OF PHARMACAL RESEARCH

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease

(2010) Nayoung Bae et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of the hook of Uncaria rhynchophylla on neurotoxicity in the 6-hydroxydopamine model of Parkinson's disease

(2009) Jin Sup Shim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson’s disease

(2009) Lilia Marinova-Mutafchieva et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

(2008) James B Koprich et al.   Journal of Neuroinflammation

Phenidone protects the nigral dopaminergic neurons from LPS-induced neurotoxicity

(2008) Zhengyi Li et al.   NEUROSCIENCE LETTERS

Juzen-taiho-to, an Herbal Medicine, Activates and Enhances Phagocytosis in Microglia/Macrophages

(2008) Huayan Liu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE