Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling
Authors
Keywords
Kidneys, Phosphorylation, Fibroblasts, Fibrosis, Histones, Collagens, Immunoblot analysis, SMAD signaling
Journal
PLoS One
Volume 8, Issue 1, Pages e54001
Publisher
Public Library of Science (PLoS)
Online
2013-01-17
DOI
10.1371/journal.pone.0054001
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism
- (2012) Maria A. Cavasin et al. CIRCULATION RESEARCH
- Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
- (2012) Hui Yao Lan International Journal of Biological Sciences
- Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis
- (2012) N. Liu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats
- (2011) Harm J. Bogaard et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects
- (2011) Francisco J. López-Hernández et al. CELL AND TISSUE RESEARCH
- Entinostat for treatment of solid tumors and hematologic malignancies
- (2011) Jeffrey Knipstein et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Valproic Acid Attenuates Proteinuria and Kidney Injury
- (2011) K. Van Beneden et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Suramin Inhibits Renal Fibrosis in Chronic Kidney Disease
- (2011) N. Liu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- EGFR Signaling Promotes TGF -Dependent Renal Fibrosis
- (2011) J. Chen et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor
- (2011) Richard E. Gilbert et al. KIDNEY INTERNATIONAL
- Cellular and molecular mechanisms of renal fibrosis
- (2011) Youhua Liu Nature Reviews Nephrology
- Nonhistone protein acetylation as cancer therapy targets
- (2010) Brahma N Singh et al. Expert Review of Anticancer Therapy
- The Microtubule-associated Histone Deacetylase 6 (HDAC6) Regulates Epidermal Growth Factor Receptor (EGFR) Endocytic Trafficking and Degradation
- (2010) Ya-sheng Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT
- (2010) Francesca Bruzzese et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
- (2010) Jiahuai Tan et al. Journal of Hematology & Oncology
- Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders
- (2010) M. Pang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
- (2010) Maoyin Pang et al. KIDNEY INTERNATIONAL
- Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
- (2010) Li Yang et al. NATURE MEDICINE
- Renal fibrosis: novel insights into mechanisms and therapeutic targets
- (2010) Peter Boor et al. Nature Reviews Nephrology
- Acetylation modulates prolactin receptor dimerization
- (2010) L. Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis
- (2009) Hossein Hemmatazad et al. ARTHRITIS AND RHEUMATISM
- Clinical Studies of Histone Deacetylase Inhibitors
- (2009) H. M. Prince et al. CLINICAL CANCER RESEARCH
- Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
- (2009) Yongseok Choi et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cellsin vitroandin vivo
- (2009) Inge Mannaerts et al. HEPATOLOGY
- Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology
- (2009) Fraczek Joanna et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Evaluation of the In vitro and In vivo Antitumor Activity of Histone Deacetylase Inhibitors for the Therapy of Retinoblastoma
- (2008) C. L. Dalgard et al. CLINICAL CANCER RESEARCH
- Transforming growth factor- signaling and ubiquitinators in cancer
- (2008) E. Glasgow et al. ENDOCRINE-RELATED CANCER
- Histone deacetylases as transducers and targets of nuclear signaling
- (2008) Donald R. Walkinshaw et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Transforming growth factor-β/connective tissue growth factor axis in the kidney
- (2007) Weier Qi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started