From ELISA to Immunosorbent Tandem Mass Spectrometry Proteoform Analysis: The Example of CXCL8/Interleukin-8

Truncation of CXCL8 to CXCL8(9-77) enhances actin polymerization and in vivo migration of neutrophils

(2020) Mieke Metzemaekers et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Remnant Epitopes Generating Autoimmunity: From Model to Useful Paradigm

(2020) Ghislain Opdenakker et al.   TRENDS IN IMMUNOLOGY

Synovial fluid neutrophils from patients with juvenile idiopathic arthritis display a hyperactivated phenotype

(2020) Mieke Metzemaekers et al.   Arthritis & Rheumatology

Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease

(2019) Liam J. O’Neil et al.   TRENDS IN MOLECULAR MEDICINE

The Neutrophil’s Role During Health and Disease

(2019) Pei Xiong Liew et al.   PHYSIOLOGICAL REVIEWS

Identification and Quantification of Proteoforms by Mass Spectrometry

(2019) Leah V. Schaffer et al.   PROTEOMICS

Relative and Absolute Quantitation in Mass Spectrometry–Based Proteomics

(2018) J. Astor Ankney et al.   Annual Review of Analytical Chemistry

Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria

(2018) Evelina Vågesjö et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

(2018) Mieke Metzemaekers et al.   Frontiers in Immunology

Differential Effects of Posttranslational Modifications of CXCL8/Interleukin-8 on CXCR1 and CXCR2 Internalization and Signaling Properties

(2018) Alessandro Vacchini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemokine isoforms and processing in inflammation and immunity

(2017) Paul Proost et al.   JOURNAL OF AUTOIMMUNITY

The CXCL8-CXCR1/2 pathways in cancer

(2016) Qian Liu et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Microbiomic and Posttranslational Modifications as Preludes to Autoimmune Diseases

(2016) Ghislain Opdenakker et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Chemokine Activity – A Focus on the Role of Dipeptidyl Peptidase IV/CD26

(2016) Mieke Metzemaekers et al.   Frontiers in Immunology

Neutrophils in pediatric autoimmune disease

(2015) Anna Huttenlocher et al.   CURRENT OPINION IN RHEUMATOLOGY

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

(2015) Rosa Barreira da Silva et al.   NATURE IMMUNOLOGY

CXCL8 – The First Chemokine

(2015) Marco Baggiolini   Frontiers in Immunology

The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases

(2014) Remo C Russo et al.   Expert Review of Clinical Immunology

Quantification of Intact and Truncated Stromal Cell-Derived Factor-1α in Circulation by Immunoaffinity Enrichment and Tandem Mass Spectrometry

(2014) Weixun Wang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

(2011) Holger Cynis et al.   EMBO Molecular Medicine

Biological Activity of CXCL8 Forms Generated by Alternative Cleavage of the Signal Peptide or by Aminopeptidase-Mediated Truncation

(2011) Anneleen Mortier et al.   PLoS One

Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

(2010) Petr Broz et al.   Cell Host & Microbe

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV

(2010) Armanda Casrouge et al.   JOURNAL OF CLINICAL INVESTIGATION

Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation

(2008) Paul Proost et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of chemokine activity by posttranslational modification

(2008) A MORTIER et al.   PHARMACOLOGY & THERAPEUTICS