MicroRNA Dysregulation in Epilepsy: From Pathogenetic Involvement to Diagnostic Biomarker and Therapeutic Agent Development
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MicroRNA Dysregulation in Epilepsy: From Pathogenetic Involvement to Diagnostic Biomarker and Therapeutic Agent Development
Authors
Keywords
-
Journal
Frontiers in Molecular Neuroscience
Volume 14, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-03-12
DOI
10.3389/fnmol.2021.650372
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MicroRNA-25-3p suppresses epileptiform discharges through inhibiting oxidative stress and apoptosis via targeting OXSR1 in neurons
- (2020) Rong Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs
- (2020) Sarah Bajan et al. Cells
- Overexpressed microRNA-494 represses RIPK1 to attenuate hippocampal neuron injury in epilepsy rats by inactivating the NF-κB signaling pathway
- (2020) Yinbao Qi et al. CELL CYCLE
- Circulating miR‐146a and miR‐134 in predicting drug‐resistant epilepsy in patients with focal impaired awareness seizures
- (2020) Maria Leontariti et al. EPILEPSIA
- Expression of circulating microRNAs as predictors of diagnosis and surgical outcome in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
- (2020) Enrico Salomao Ioriatti et al. EPILEPSY RESEARCH
- Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy
- (2020) Huimin Kong et al. LABORATORY INVESTIGATION
- miR‑15a inhibits cell apoptosis and inflammation in a temporal lobe epilepsy model by downregulating GFAP
- (2020) Yuehui Fan et al. Molecular Medicine Reports
- Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
- (2020) Gary P. Brennan et al. NEUROBIOLOGY OF DISEASE
- Downregulation of MicroRNA-34c-5p facilitated neuroinflammation in drug-resistant epilepsy
- (2020) Meng Fu et al. BRAIN RESEARCH
- Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF
- (2019) Ping Zheng et al. Cancer Cell International
- miR‑128 is upregulated in epilepsy and promotes apoptosis through the SIRT1 cascade
- (2019) De‑Zhe Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures
- (2019) Vamshidhar R. Vangoor et al. JOURNAL OF NEUROSCIENCE
- Silencing MicroRNA-134 Alleviates Hippocampal Damage and Occurrence of Spontaneous Seizures After Intraventricular Kainic Acid-Induced Status Epilepticus in Rats
- (2019) Xiaoying Gao et al. Frontiers in Cellular Neuroscience
- Expression of MicroRNAs miR-145, miR-181c, miR-199a and miR-1183 in the Blood and Hippocampus of Patients with Mesial Temporal Lobe Epilepsy
- (2019) Luana Grupioni Lourenço Antônio et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy
- (2019) Annamaria Vezzani et al. Nature Reviews Neurology
- miR-125a-5p alleviates dysfunction and inflammation of pentylenetetrazol-induced epilepsy through targeting calmodulin-dependent protein kinase IV (CAMK4)
- (2019) Qishuai Liu et al. CURRENT NEUROVASCULAR RESEARCH
- Expression of plasma microRNA-145-5p and its correlation with clinical features in patients with refractory epilepsy
- (2019) Chun-Hong Shen et al. EPILEPSY RESEARCH
- microRNA‐132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro‐epileptogenic factors in human cultured astrocytes
- (2019) Anatoly Korotkov et al. GLIA
- MicroRNA-23a contributes to hippocampal neuronal injuries and spatial memory impairment in an experimental model of temporal lobe epilepsy
- (2019) Xinjian Zhu et al. BRAIN RESEARCH BULLETIN
- Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases
- (2019) Konovalova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies
- (2019) Jun Lu et al. MEDICAL SCIENCE MONITOR
- MicroRNA-451 aggravates kainic acid-induced seizure and neuronal apoptosis by targeting GDNF
- (2019) Ning Weng et al. CURRENT NEUROVASCULAR RESEARCH
- Circulating microRNAs as potential biomarkers for genetic generalized epilepsies: a three microRNA panel
- (2019) R. Martins‐Ferreira et al. EUROPEAN JOURNAL OF NEUROLOGY
- MiR-181b inhibits P38/JNK signaling pathway to attenuate autophagy and apoptosis in juvenile rats with kainic acid-induced epilepsy via targeting TLR4
- (2018) Li Wang et al. CNS Neuroscience & Therapeutics
- The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy
- (2018) Tao-Ran Li et al. Disease Models & Mechanisms
- Intracerebroventricular injection of miR-146a relieves seizures in an immature rat model of lithium-pilocarpine induced status epilepticus
- (2018) Xiaole Wang et al. EPILEPSY RESEARCH
- MicroRNA‑155 contributes to the occurrence of epilepsy through the PI3K/Akt/mTOR signaling pathway
- (2018) Wei Duan et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- MicroRNA-132 attenuates LPS-induced inflammatory injury by targeting TRAF6 in neuronal cell line HT-22
- (2018) Yang-Fei Ji et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Effects of microRNA-129 and its target gene c-Fos on proliferation and apoptosis of hippocampal neurons in rats with epilepsy via the MAPK signaling pathway
- (2018) Dong-Mei Wu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- MicroRNA-421 suppresses the apoptosis and autophagy of hippocampal neurons in epilepsy mice model by inhibition of the TLR/MYD88 pathway
- (2018) Xin Wen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The role of inflammation in the development of epilepsy
- (2018) Amna Rana et al. Journal of Neuroinflammation
- Antagonist targeting microRNA-146a protects against lithium-pilocarpine-induced status epilepticus in rats by nuclear factor-κB pathway
- (2018) Huilong Zhang et al. Molecular Medicine Reports
- Overexpression of miRNA-137 in the brain suppresses seizure activity and neuronal excitability: A new potential therapeutic strategy for epilepsy
- (2018) Wei Wang et al. NEUROPHARMACOLOGY
- microRNAs in the pathophysiology of epilepsy
- (2018) Gary P. Brennan et al. NEUROSCIENCE LETTERS
- Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes
- (2018) Anatoly Korotkov et al. Journal of Neuroinflammation
- Suppression of microRNA‐141 suppressed p53 to protect against neural apoptosis in epilepsy by SIRT1 expression
- (2018) Ding Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Aberrant Expression of miR-323a-5p in Patients with Refractory Epilepsy Caused by Focal Cortical Dysplasia
- (2017) Ningwei Che et al. Genetic Testing and Molecular Biomarkers
- Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model
- (2017) Hua Tao et al. MEDIATORS OF INFLAMMATION
- miR-21 attenuates contrast-induced renal cell apoptosis by targeting PDCD4
- (2017) Kun Wang et al. Molecular Medicine Reports
- MicroRNA-21 increases cell viability and suppresses cellular apoptosis in non-small cell lung cancer by regulating the PI3K/Akt signaling pathway
- (2017) Tao Wang et al. Molecular Medicine Reports
- The efficacy of gastrodin in combination with folate and vitamin B12 on patients with epilepsy after stroke and its effect on HMGB-1, IL-2 and IL-6 serum levels
- (2017) Hao Zhou et al. Experimental and Therapeutic Medicine
- MicroRNA hsa-miR-134 is a circulating biomarker for mesial temporal lobe epilepsy
- (2017) Simoni H. Avansini et al. PLoS One
- Modulation of miR-146a /complement factor H-mediated inflammatory responses in a rat model of temporal lobe epilepsy
- (2016) Fang He et al. BIOSCIENCE REPORTS
- MicroRNA-204 suppresses epileptiform discharges through regulating TrkB-ERK1/2-CREB signaling in cultured hippocampal neurons
- (2016) Lei Xiang et al. BRAIN RESEARCH
- Synaptic Remodeling of Entorhinal Input Contributes to an Aberrant Hippocampal Network in Temporal Lobe Epilepsy
- (2016) Philipp Janz et al. CEREBRAL CORTEX
- Involvement of microRNAs in epileptogenesis
- (2016) Adriano A. Cattani et al. EPILEPSIA
- Elevated serum miR-106b and miR-146a in patients with focal and generalized epilepsy
- (2016) Ning An et al. EPILEPSY RESEARCH
- Expression of microRNA-129-2-3p and microRNA-935 in plasma and brain tissue of human refractory epilepsy
- (2016) Yuqiang Sun et al. EPILEPSY RESEARCH
- The microRNA miR-124 suppresses seizure activity and regulates CREB1 activity
- (2016) Wei Wang et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Advances in the development of biomarkers for epilepsy
- (2016) Asla Pitkänen et al. LANCET NEUROLOGY
- MicroRNAs in epilepsy: pathophysiology and clinical utility
- (2016) David C Henshall et al. LANCET NEUROLOGY
- Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure
- (2016) Jijun Sun et al. Molecular Medicine Reports
- MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process
- (2016) Jinxian Yuan et al. NEURAL PLASTICITY
- Infections, inflammation and epilepsy
- (2015) Annamaria Vezzani et al. ACTA NEUROPATHOLOGICA
- MicroRNA-132 aggravates epileptiform discharges via suppression of BDNF/TrkB signaling in cultured hippocampal neurons
- (2015) Lei Xiang et al. BRAIN RESEARCH
- miR-210 mediates vagus nerve stimulation-induced antioxidant stress and anti-apoptosis reactions following cerebral ischemia/reperfusion injury in rats
- (2015) Ying Jiang et al. JOURNAL OF NEUROCHEMISTRY
- Serum MicroRNA-4521 is a Potential Biomarker for Focal Cortical Dysplasia with Refractory Epilepsy
- (2015) Xiaofeng Wang et al. NEUROCHEMICAL RESEARCH
- Increased complexin-1 and decreased miR-185 expression levels in Behçet’s disease with and without neurological involvement
- (2015) Elif Uğurel et al. NEUROLOGICAL SCIENCES
- An evaluation of the links between microRNA, autophagy, and epilepsy
- (2015) Jing Gan et al. REVIEWS IN THE NEUROSCIENCES
- Genome-wide circulating microRNA expression profiling indicates biomarkers for epilepsy
- (2015) Jun Wang et al. Scientific Reports
- microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus
- (2015) Eva M. Jimenez-Mateos et al. Scientific Reports
- Circulating microRNAs are promising novel biomarkers for drug-resistant epilepsy
- (2015) Jun Wang et al. Scientific Reports
- miRNAs: biological and clinical determinants in epilepsy
- (2015) Walid A. Alsharafi et al. Frontiers in Molecular Neuroscience
- Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy
- (2015) Suzanne F.C. Miller-Delaney et al. BRAIN
- MicroRNA and epilepsy
- (2014) David C. Henshall CURRENT OPINION IN NEUROLOGY
- MiR-219 Protects Against Seizure in the Kainic Acid Model of Epilepsy
- (2014) Honghua Zheng et al. MOLECULAR NEUROBIOLOGY
- Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
- (2013) Gang Wan et al. Autophagy
- Expressions of Tumor Necrosis Factor Alpha and MicroRNA-155 in Immature Rat Model of Status Epilepticus and Children with Mesial Temporal Lobe Epilepsy
- (2013) Muhammad Usman Ashhab et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Expression Patterns of miR-124, miR-134, miR-132, and miR-21 in an Immature Rat Model and Children with Mesial Temporal Lobe Epilepsy
- (2013) Jing Peng et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus
- (2012) Kai Hu et al. BMC NEUROSCIENCE
- MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex
- (2012) Helen L. Scott et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death
- (2012) Ross C. McKiernan et al. EXPERIMENTAL NEUROLOGY
- Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
- (2012) Eva M Jimenez-Mateos et al. NATURE MEDICINE
- EPAC Null Mutation Impairs Learning and Social Interactions via Aberrant Regulation of miR-124 and Zif268 Translation
- (2012) Ying Yang et al. NEURON
- Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish
- (2012) A. A. Bazzini et al. SCIENCE
- miRNA Expression Profile after Status Epilepticus and Hippocampal Neuroprotection by Targeting miR-132
- (2011) Eva M. Jimenez-Mateos et al. AMERICAN JOURNAL OF PATHOLOGY
- Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy
- (2011) Shawn McClelland et al. ANNALS OF NEUROLOGY
- MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma
- (2011) Amanda Tivnan et al. BMC CANCER
- Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus
- (2011) Rashmi M. Risbud et al. BRAIN RESEARCH
- Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b
- (2011) Yi-jun Song et al. BRAIN RESEARCH
- miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice
- (2011) Mark P. Boldin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glia as a source of cytokines: Implications for neuronal excitability and survival
- (2010) Annamaria Vezzani et al. EPILEPSIA
- Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy
- (2010) E. Aronica et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The widespread regulation of microRNA biogenesis, function and decay
- (2010) Jacek Krol et al. NATURE REVIEWS GENETICS
- The role of inflammation in epilepsy
- (2010) Annamaria Vezzani et al. Nature Reviews Neurology
- Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo
- (2009) Aaron S. Nudelman et al. HIPPOCAMPUS
- Many roads to maturity: microRNA biogenesis pathways and their regulation
- (2009) Julia Winter et al. NATURE CELL BIOLOGY
- microRNA involvement in developmental and functional aspects of the nervous system and in neurological diseases
- (2009) Mette Christensen et al. NEUROSCIENCE LETTERS
- An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP
- (2008) Gary A. Wayman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started