The role of macrophage-derived TGF-β1 on SiO2-induced pulmonary fibrosis: A review

Silica particles disorganize the polarization of pulmonary macrophages in mice

(2020) Youliang Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Proteomic profile of TGF-β1 treated lung fibroblasts identifies novel markers of activated fibroblasts in the silica exposed rat lung

(2019) Mao Na et al.   EXPERIMENTAL CELL RESEARCH

Artificial Stone Associated Silicosis: A Systematic Review

(2019) Veruscka Leso et al.   International Journal of Environmental Research and Public Health

Overexpression of TIM-3 in macrophages aggravates pathogenesis of pulmonary fibrosis in mice

(2019) Yu Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A reliable approach for assessing size-dependent effects of silica nanoparticles on cellular internalization behavior and cytotoxic mechanisms

(2019) Wooil Kim et al.   International Journal of Nanomedicine

The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

(2019) Cristina Pavan et al.   Particle and Fibre Toxicology

Effects of abnormal expression of fusion and fission genes on the morphology and function of lung macrophage mitochondria in SiO2-induced silicosis fibrosis in rats in vivo

(2019) Zhao-qiang Zhang et al.   TOXICOLOGY LETTERS

Severe Silicosis in Engineered Stone Fabrication Workers — California, Colorado, Texas, and Washington, 2017–2019

(2019) Cecile Rose et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation

(2019) Feifei Feng et al.   Drug Design Development and Therapy

Monocyte-derived Alveolar Macrophages: The Dark Side of Lung Repair?

(2018) Alexandra C. McQuattie-Pimentel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

(2018) Julian Nüchel et al.   Autophagy

Long non-coding RNA-ATB promotes EMT during silica-induced pulmonary fibrosis by competitively binding miR-200c

(2018) Yi Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The phenotype of peritoneal mouse macrophages depends on the mitochondria and ATP/ADP homeostasis

(2018) Wei Chen et al.   CELLULAR IMMUNOLOGY

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

(2018) Laia Caja et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pirfenidone suppresses polarization to M2 phenotype macrophages and the fibrogenic activity of rat lung fibroblasts

(2018) Michihito Toda et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Phytochemicals as modulators of M1-M2 macrophages in inflammation

(2018) Uzma Saqib et al.   Oncotarget

Macrophage Recognition of Crystals and Nanoparticles

(2018) Masafumi Nakayama   Frontiers in Immunology

TGF-β receptors: In and beyond TGF-β signaling

(2018) Alexandra Vander Ark et al.   CELLULAR SIGNALLING

PPARγ induces the gene expression of integrin ανβ5 to promote macrophage M2 polarization

(2018) Qinyu Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-542-5p Attenuates Fibroblast Activation by Targeting Integrin α6 in Silica-Induced Pulmonary Fibrosis

(2018) Jiali Yuan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants

(2018) Debra L Laskin et al.   TOXICOLOGICAL SCIENCES

PM2.5 induced pulmonary fibrosis in vivo and in vitro

(2018) Zihan Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages

(2017) Xueyang Yu et al.   IMMUNITY

TGF-β signalling in tumour associated macrophages

(2017) Alexei Gratchev   IMMUNOBIOLOGY

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

(2017) Shibnath Ghatak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prodomain–growth factor swapping in the structure of pro-TGF-β1

(2017) Bo Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

(2017) Alexander V. Misharin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of GARP in the activation of latent TGF-β1

(2017) Julie Stockis et al.   Molecular BioSystems

Artificial stone-associated silicosis: a rapidly emerging occupational lung disease

(2017) Ryan F Hoy et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice

(2017) Chao Li et al.   Theranostics

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis

(2017) Priscila J. Carneiro et al.   Frontiers in Physiology

Characteristics and potential role of M2 macrophages in COPD

(2017) Shengyang He et al.   International Journal of Chronic Obstructive Pulmonary Disease

Histones bundle F-actin filaments and affect actin structure

(2017) Edna Blotnick et al.   PLoS One

Matrix Remodeling in Pulmonary Fibrosis and Emphysema

(2016) Tejaswini Kulkarni et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dynamic changes of mononuclear phagocytes in circulating, pulmonary alveolar and interstitial compartments in a mouse model of experimental silicosis

(2016) Guo-An Xiang et al.   INHALATION TOXICOLOGY

Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis

(2016) Niall A. Anderson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

(2016) Xiao-Ming Meng et al.   Cell Death & Disease

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

(2016) Fan Zhang et al.   Oncotarget

F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2

(2016) Danielle Burger et al.   Scientific Reports

Cell-Based Therapy for Silicosis

(2016) Miquéias Lopes-Pacheco et al.   Stem Cells International

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

(2016) Aristidis Moustakas et al.   Journal of Clinical Medicine

Activation of Type II Cells into Regenerative Stem Cell Antigen-1+Cells during Alveolar Repair

(2015) Yuru Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways

(2015) Haiying Tang et al.   CELL STRESS & CHAPERONES

Blocking TGF-β expression inhibits silica particle-induced epithelial–mesenchymal transition in human lung epithelial cells

(2015) Yi Rong et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

Revisiting the paradigm of silica pathogenicity with synthetic quartz crystals: the role of crystallinity and surface disorder

(2015) Francesco Turci et al.   Particle and Fibre Toxicology

Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung

(2015) Rajan Jain et al.   Nature Communications

TGF-β/Smad3 signalling regulates the transition of bone marrowderived macrophages into myofibroblasts during tissue fibrosis

(2015) Shuang Wang et al.   Oncotarget

Anatomy of a Discovery: M1 and M2 Macrophages

(2015) Charles Dudley Mills   Frontiers in Immunology

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis

(2013) Norihiko Sakai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Relaxin attenuates silica-induced pulmonary fibrosis by regulating collagen type I and MMP-2

(2013) Xiao-Feng Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregulating the TGF-β1/Smad3 signaling pathway in rats

(2013) Xiaodong Song et al.   LABORATORY INVESTIGATION

Novel combination of collagen dynamics analysis and transcriptional profiling reveals fibrosis-relevant genes and pathways

(2013) Marjolein E. Blaauboer et al.   MATRIX BIOLOGY

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1

(2013) Tiana V Curry-McCoy et al.   RESPIRATORY RESEARCH

Recent Developments in Myofibroblast Biology

(2012) Boris Hinz et al.   AMERICAN JOURNAL OF PATHOLOGY

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β

(2011) Hideya Kitamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular Plasticity of Inflammatory Myeloid Cells in the Peritoneal Foreign Body Response

(2009) Jane E. Mooney et al.   AMERICAN JOURNAL OF PATHOLOGY

Rat alveolar type I cells proliferate, express OCT-4, and exhibit phenotypic plasticity in vitro

(2009) Robert F. Gonzalez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of pulmonary inflammation and fibrosis through expression of integrins αVβ3 and αVβ5 on pulmonary T lymphocytes

(2009) Irina G. Luzina et al.   ARTHRITIS AND RHEUMATISM

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY