The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

Inflammasomes, Neutrophil Extracellular Traps, and Cholesterol

(2019) Alan R. Tall et al.   JOURNAL OF LIPID RESEARCH

Increased Acid Dissociation at the Quartz/Water Interface

(2018) Shivam Parashar et al.   Journal of Physical Chemistry Letters

An updated review of the genotoxicity of respirable crystalline silica

(2018) Paul J. A. Borm et al.   Particle and Fibre Toxicology

Volcanic Ash Activates the NLRP3 Inflammasome in Murine and Human Macrophages

(2018) David E. Damby et al.   Frontiers in Immunology

Molecular Dynamics Simulations of the Silica–Cell Membrane Interaction: Insights on Biomineralization and Nanotoxicity

(2018) Massimo Delle Piane et al.   Journal of Physical Chemistry C

The effect of aluminium and sodium impurities on the in vitro toxicity and pro-inflammatory potential of cristobalite

(2017) C. Nattrass et al.   ENVIRONMENTAL RESEARCH

The silanol content and in vitro cytolytic activity of flame-made silica

(2017) Anastasia Spyrogianni et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells

(2017) Alicia Sanchez et al.   Particle and Fibre Toxicology

How strong are H-bonds at the fully hydroxylated silica surfaces? Insights from the B3LYP electron density topological analysis

(2017) Federico Musso et al.   STRUCTURAL CHEMISTRY

Atomic Force Microscopy as a Tool to Assess the Specificity of Targeted Nanoparticles in Biological Models of High Complexity

(2017) Carla P. Gomes et al.   Advanced Healthcare Materials

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Atomic force microscopy-based characterization and design of biointerfaces

(2017) David Alsteens et al.   Nature Reviews Materials

Organosilane-Based Coating of Quartz Species from the Traditional Ceramics Industry: Evidence of Hazard Reduction Using In Vitro and In Vivo Tests

(2017) Christina Ziemann et al.   Annals of Work Exposures and Health

Enhancing Important Fluctuations: Rare Events and Metadynamics from a Conceptual Viewpoint

(2016) Omar Valsson et al.   Annual Review of Physical Chemistry

Interactions between silica nanoparticles and phospholipid membranes

(2016) Helene Kettiger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Unveiling the Variability of “Quartz Hazard” in Light of Recent Toxicological Findings

(2016) Cristina Pavan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Synthesis of α-Quartz with Controlled Properties for the Investigation of the Molecular Determinants in Silica Toxicology

(2016) Linda Pastero et al.   CRYSTAL GROWTH & DESIGN

pKa at Quartz/Electrolyte Interfaces

(2016) Morgane Pfeiffer-Laplaud et al.   Journal of Physical Chemistry Letters

Silica, Silicosis, and Autoimmunity

(2016) Kenneth Michael Pollard   Frontiers in Immunology

A mechanistic review of silica-induced inhalation toxicity

(2015) Hajime Kawasaki   INHALATION TOXICOLOGY

Bimodal Acidity at the Amorphous Silica/Water Interface

(2015) Morgane Pfeiffer-Laplaud et al.   Journal of Physical Chemistry C

Revisiting the paradigm of silica pathogenicity with synthetic quartz crystals: the role of crystallinity and surface disorder

(2015) Francesco Turci et al.   Particle and Fibre Toxicology

The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases

(2015) Mutlay Sayan et al.   Particle and Fibre Toxicology

The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles

(2015) Virginie Rabolli et al.   Particle and Fibre Toxicology

The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation

(2015) C. Nattrass et al.   Journal of Occupational Medicine and Toxicology

Why does the hemolytic activity of silica predict its pro-inflammatory activity?

(2014) Cristina Pavan et al.   Particle and Fibre Toxicology

The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles

(2014) Virginie Rabolli et al.   Particle and Fibre Toxicology

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

In Search of the Chemical Basis of the Hemolytic Potential of Silicas

(2013) Cristina Pavan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Silica–Water Interface: How the Silanols Determine the Surface Acidity and Modulate the Water Properties

(2012) Marialore Sulpizi et al.   Journal of Chemical Theory and Computation

Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic

(2012) Haiyuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

The structure of volcanic cristobalite in relation to its toxicity; relevance for the variable crystalline silica hazard

(2012) Claire J Horwell et al.   Particle and Fibre Toxicology

NF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells

(2010) Damien van Berlo et al.   Particle and Fibre Toxicology

Monosodium urate crystals in inflammation and immunity

(2009) Yan Shi et al.   IMMUNOLOGICAL REVIEWS

H-Bond Features of Fully Hydroxylated Surfaces of Crystalline Silica Polymorphs: A Periodic B3LYP Study

(2009) Federico Musso et al.   Journal of Physical Chemistry C

Influence of selected alkoxysilanes on dispersive properties and surface chemistry of spherical silica precipitated in emulsion media

(2009) Teofil Jesionowski et al.   MATERIALS CHEMISTRY AND PHYSICS

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE