Targeting stemness of cancer stem cells to fight colorectal cancers
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Title
Targeting stemness of cancer stem cells to fight colorectal cancers
Authors
Keywords
Colorectal cancer, Cancer stem cells, Tumor initiating cells, Cancer stem cell markers, Monoclonal antibody, Tumor organoid
Journal
SEMINARS IN CANCER BIOLOGY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-02-23
DOI
10.1016/j.semcancer.2021.02.012
References
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Note: Only part of the references are listed.- Mesenchymal stem cells maintain the stemness of colon cancer stem cells via interleukin-8/mitogen-activated protein kinase signaling pathway
- (2020) Xiaoying Ma et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Crosstalk between autophagy and metabolic regulation of cancer stem cells
- (2020) Mouradi El Hout et al. Molecular Cancer
- Cancer stem cell niche in colorectal cancer and targeted therapies.
- (2020) Hao Wang et al. CURRENT PHARMACEUTICAL DESIGN
- Colon adenocarcinoma-derived cells that express induced-pluripotent stem cell markers possess stem cell function
- (2020) Matthew J. Munro et al. PLoS One
- Simultaneous versus staged colorectal and hepatic resections for colorectal cancer with synchronous hepatic metastases: a meta-analysis of outcomes and clinical characteristics
- (2020) Shahin Hajibandeh et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Role of PrPC in Cancer Stem Cell Characteristics and Drug Resistance in Colon Cancer Cells
- (2020) GYEONGYUN GO et al. ANTICANCER RESEARCH
- Identification of Targets to Redirect CAR T Cells in Glioblastoma and Colorectal Cancer: An Arduous Venture
- (2020) Eleonora Ponterio et al. Frontiers in Immunology
- Recent developments in antibody derivatives against colorectal cancer; A review
- (2020) Sepideh Ghani et al. LIFE SCIENCES
- Immune Adaptation of Colorectal Cancer Stem Cells and Their Interaction With the Tumor Microenvironment
- (2020) Chun-Chi Lin et al. Frontiers in Oncology
- Cancer-on-a-chip for Drug Screening
- (2019) I-Chi Lee CURRENT PHARMACEUTICAL DESIGN
- Avapritinib, a selective inhibitor of KIT and PDGFRα reverses ABCB1 and ABCG2-mediated multidrug resistance in cancer cell lines
- (2019) Chung-Pu Wu et al. MOLECULAR PHARMACEUTICS
- Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133
- (2019) Hongran Yin et al. MOLECULAR THERAPY
- Insights into new mechanisms and models of cancer stem cell multidrug resistance
- (2019) Y. Garcia-Mayea et al. SEMINARS IN CANCER BIOLOGY
- Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer
- (2019) Ye Yao et al. Cell Stem Cell
- Pathways of Colorectal Carcinogenesis
- (2019) Long H. Nguyen et al. GASTROENTEROLOGY
- Colon cancer therapy by focusing on colon cancer stem cells and their tumor microenvironment
- (2019) Zohreh Jahanafrooz et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells
- (2019) Stefano Thellung et al. Cells
- BMI1 activates WNT signaling in colon cancer by negatively regulating the WNT antagonist IDAX
- (2018) Feiyue Yu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Comparison of EpCAMhighCD44+ cancer stem cells with EpCAMhighCD44− tumor cells in colon cancer by single-cell sequencing
- (2018) Mingshan Liu et al. CANCER BIOLOGY & THERAPY
- R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells
- (2018) Jun Ye et al. CELL CYCLE
- Inhibition of DNMT suppresses the stemness of colorectal cancer cells through down-regulating Wnt signaling pathway
- (2018) Shanxin Li et al. CELLULAR SIGNALLING
- T-cell Homing Therapy for Reducing Regulatory T Cells and Preserving Effector T-cell Function in Large Solid Tumors
- (2018) Jiemiao Hu et al. CLINICAL CANCER RESEARCH
- Identification, isolation and characterization of human LGR5-positive colon adenoma cells
- (2018) Michael K. Dame et al. DEVELOPMENT
- Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis
- (2018) Hsi-Hsien Hsu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway
- (2018) Xu Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Ectopic expression of miR-147 inhibits stem cell marker and epithelial-mesenchymal transition (EMT)-related protein expression in colon cancer cells
- (2018) Xiaofei Ning et al. ONCOLOGY RESEARCH
- Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism
- (2018) Jae Hyun Kim et al. Scientific Reports
- Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
- (2018) Krijn K. Dijkstra et al. CELL
- Organoid technology and applications in cancer research
- (2018) Hanxiao Xu et al. Journal of Hematology & Oncology
- Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis
- (2018) Jun Hee Lee et al. JOURNAL OF PINEAL RESEARCH
- Cancer cell plasticity: Impact on tumor progression and therapy response
- (2018) Victoria da Silva-Diz et al. SEMINARS IN CANCER BIOLOGY
- Aspirin cooperates with p300 to activate the acetylation of H3K9 and promote FasL-mediated apoptosis of cancer stem-like cells in colorectal cancer
- (2018) Zhigang Chen et al. Theranostics
- Inhibition of LEF1-Mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness
- (2018) So-Yeon Park et al. CLINICAL CANCER RESEARCH
- The Roles of Autophagy in Cancer
- (2018) Chul Yun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors
- (2018) David C. Smith et al. INVESTIGATIONAL NEW DRUGS
- Colorectal cancer vaccines: Tumor-associated antigens vs neoantigens
- (2018) Sandra Wagner et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy
- (2017) Cristina Maccalli et al. IMMUNOLOGICAL INVESTIGATIONS
- Multifaceted Interpretation of Colon Cancer Stem Cells
- (2017) Yuichiro Hatano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)
- (2017) Masaru Katoh INTERNATIONAL JOURNAL OF ONCOLOGY
- Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen
- (2017) Alex J. Walsh et al. JOURNAL OF NUCLEAR MEDICINE
- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
- (2017) Laura Broutier et al. NATURE MEDICINE
- Targeted photodynamic therapy as potential treatment modality for the eradication of colon cancer and colon cancer stem cells
- (2017) Natasha Hodgkinson et al. TUMOR BIOLOGY
- Expression of the cancer stem cell markers ABCG2 and OCT-4 in right-sided colon cancer predicts recurrence and poor outcomes
- (2017) Jun Hu et al. Oncotarget
- Autophagic homeostasis is required for the pluripotency of cancer stem cells
- (2016) Tanveer Sharif et al. Autophagy
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells
- (2016) Serena Di Cecilia et al. CANCER RESEARCH
- NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells
- (2016) T. Srinivasan et al. CANCER RESEARCH
- miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1
- (2016) M. Sakaguchi et al. MOLECULAR CANCER RESEARCH
- LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence
- (2016) Xing Gong et al. MOLECULAR CANCER THERAPEUTICS
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- (2016) Y-X Jiang et al. ONCOGENE
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- Liposomal flucytosine capped with gold nanoparticle formulations for improved ocular delivery
- (2016) Heba Salem et al. Drug Design Development and Therapy
- Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells
- (2016) Cynthia Morata-Tarifa et al. Scientific Reports
- New Insights into the Crossroads between EMT and Stemness in the Context of Cancer
- (2016) Isabel Fabregat et al. Journal of Clinical Medicine
- Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates -Catenin Signaling and Tumorigenesis in Multiple Cancer Types
- (2015) C. Chartier et al. CANCER RESEARCH
- The Hippo pathway in colorectal cancer
- (2015) Piotr M. Wierzbicki et al. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
- Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases
- (2015) FEIFENG JING et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer
- (2015) Alexander W. Fender et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Personalizing Colon Cancer Adjuvant Therapy: Selecting Optimal Treatments for Individual Patients
- (2015) Rodrigo Dienstmann et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting CD44 expressing cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin
- (2015) Leila Arabi et al. JOURNAL OF CONTROLLED RELEASE
- The cellular prion protein PrPc is a partner of the Wnt pathway in intestinal epithelial cells
- (2015) Laura S. Besnier et al. MOLECULAR BIOLOGY OF THE CELL
- Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
- (2015) Elaine E. Storm et al. NATURE
- Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses
- (2015) S B Kim et al. ONCOGENE
- Cancer stem cells, cancer cell plasticity and radiation therapy
- (2015) Erina Vlashi et al. SEMINARS IN CANCER BIOLOGY
- Concise Review: Targeting Cancer Stem Cells Using Immunologic Approaches
- (2015) Qin Pan et al. STEM CELLS
- Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression
- (2015) Amber R. Smith et al. Oncotarget
- Promise of cancer stem cell vaccine
- (2015) Li Zhou et al. Human Vaccines & Immunotherapeutics
- Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target
- (2015) Yongmin Yan et al. Stem Cells Translational Medicine
- Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1
- (2015) Maria Giovanna Francipane et al. Oncotarget
- A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer
- (2014) Susumu Miyazaki et al. ANNALS OF SURGICAL ONCOLOGY
- Epigenetic modifications in colorectal cancer: Molecular insights and therapeutic challenges
- (2014) Aristeidis G. Vaiopoulos et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Colon cancer: Cancer stem cells markers, drug resistance and treatment
- (2014) Zuzana Kozovska et al. BIOMEDICINE & PHARMACOTHERAPY
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Colorectal Cancer Stem Cells: From the Crypt to the Clinic
- (2014) Ann Zeuner et al. Cell Stem Cell
- The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
- (2014) W. de Lau et al. GENES & DEVELOPMENT
- Cancer stem cells and radioresistance
- (2014) Kiera Rycaj et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis
- (2014) Carla Kantara et al. LABORATORY INVESTIGATION
- The novel EpCAM-targeting monoclonal antibody 3–17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
- (2014) Kaja Lund et al. mAbs
- Establishment of Highly Tumorigenic Human Colorectal Cancer Cell Line (CR4) with Properties of Putative Cancer Stem Cells
- (2014) Rebecca A. Rowehl et al. PLoS One
- Evaluation of Cancer Stem Cell Markers CD133, CD44, CD24: Association with AKT Isoforms and Radiation Resistance in Colon Cancer Cells
- (2014) Sara Häggblad Sahlberg et al. PLoS One
- Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens
- (2014) Yingjie Yu et al. Translational Oncology
- OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation
- (2014) W L Ng et al. Cell Death & Disease
- ABCG2-Meditated Multidrug Resistance and Tumor-Initiating Capacity of Side Population Cells from Colon Cancer
- (2014) Zheng-Yuan Xie et al. Oncology Research and Treatment
- Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells
- (2013) Shaobin Wu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Oct-4 is required for an antiapoptotic behavior of chemoresistant colorectal cancer cells enriched for cancer stem cells: Effects associated with STAT3/Survivin
- (2013) Kunming Wen et al. CANCER LETTERS
- CD44-Positive Cancer Stem Cells Expressing Cellular Prion Protein Contribute to Metastatic Capacity in Colorectal Cancer
- (2013) L. Du et al. CANCER RESEARCH
- Prospective Analysis of Body Mass Index, Physical Activity, and Colorectal Cancer Risk Associated with -Catenin (CTNNB1) Status
- (2013) T. Morikawa et al. CANCER RESEARCH
- New insights into prostate cancer stem cells
- (2013) Xin Chen et al. CELL CYCLE
- Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
- (2013) Y. Touil et al. CLINICAL CANCER RESEARCH
- Site-specific antibody drug conjugates for cancer therapy
- (2013) Siler Panowski et al. mAbs
- Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
- (2013) L. Vermeulen et al. SCIENCE
- Maintenance of the stemness in CD44+ HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression
- (2013) Sy-Yeuan Ju et al. Stem Cell Research
- Osteopontin, a possible modulator of cancer stem cells and their malignant niche
- (2013) Guanhua Rao et al. OncoImmunology
- Developmental signaling pathways in cancer stem cells of solid tumors
- (2012) Christina Karamboulas et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
- (2012) Y.-P. Liu et al. CANCER RESEARCH
- Understanding cancer stem cell heterogeneity and plasticity
- (2012) Dean G Tang CELL RESEARCH
- Cancer Stem Cells: Current Status and Evolving Complexities
- (2012) Jane E. Visvader et al. Cell Stem Cell
- Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence
- (2012) Koichi Ito et al. CLINICAL & EXPERIMENTAL METASTASIS
- Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
- (2012) G. Rao et al. CLINICAL CANCER RESEARCH
- OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion
- (2012) XINZHENG DAI et al. ONCOLOGY REPORTS
- Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas
- (2012) A. G. Schepers et al. SCIENCE
- Proliferation State and Polo-Like Kinase1 Dependence of Tumorigenic Colon Cancer Cells
- (2012) Federica Francescangeli et al. STEM CELLS
- The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
- (2011) Anna Merlos-Suárez et al. Cell Stem Cell
- Antibody Conjugate Therapeutics: Challenges and Potential
- (2011) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- Isolation and in vitro expansion of human colonic stem cells
- (2011) Peter Jung et al. NATURE MEDICINE
- Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer
- (2010) Hui-Min Meng et al. CANCER BIOLOGY & THERAPY
- NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
- (2010) S. S. Sikandar et al. CANCER RESEARCH
- Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
- (2010) M. Fischer et al. CANCER RESEARCH
- The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation
- (2010) K. Kemper et al. CANCER RESEARCH
- Transcriptional crosstalk between TGFβ and stem cell pathways in tumor cell invasion: Role of EMT promoting Smad complexes
- (2010) Jonas Fuxe et al. CELL CYCLE
- A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
- (2010) Roberta Pang et al. Cell Stem Cell
- Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody
- (2010) Annika Wulf-Goldenberg et al. CYTOTHERAPY
- Colon cancer stem cells: implications in carcinogenesis
- (2010) Matthew et al. Frontiers in Bioscience-Landmark
- Colon Cancer Stem Cells: Promise of Targeted Therapy
- (2010) Matilde Todaro et al. GASTROENTEROLOGY
- Inflammation and Colon Cancer
- (2010) Janoš Terzić et al. GASTROENTEROLOGY
- Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice
- (2010) Ylenia Lombardo et al. GASTROENTEROLOGY
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution
- (2009) Mark Shackleton et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma
- (2009) Myung Jin Son et al. Cell Stem Cell
- The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies
- (2009) Brett G. Hollier et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo
- (2009) Yu-gang Wu et al. MEDICAL ONCOLOGY
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Significance of CD90+ Cancer Stem Cells in Human Liver Cancer
- (2008) Zhen Fan Yang et al. CANCER CELL
- Therapeutic Window of MuS110, a Single-Chain Antibody Construct Bispecific for Murine EpCAM and Murine CD3
- (2008) M. Amann et al. CANCER RESEARCH
- Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells
- (2008) M. G. Francipane et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- CD44 is of Functional Importance for Colorectal Cancer Stem Cells
- (2008) L. Du et al. CLINICAL CANCER RESEARCH
- Identification of cells initiating human melanomas
- (2008) Tobias Schatton et al. NATURE
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy
- (2008) Scott J. Dylla et al. PLoS One
- The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic Melanoma
- (2008) Germana Rappa et al. STEM CELLS
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