Nlrp3 Deficiency Alleviates Angiotensin II-Induced Cardiomyopathy by Inhibiting Mitochondrial Dysfunction

Qingda granule attenuates angiotensin II-induced cardiac hypertrophy and apoptosis and modulates the PI3K/AKT pathway

(2020) Ying Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

Mycophenolic acid enhanced lipopolysaccharide-induced interleukin-18 release in THP-1 cells via activation of the NLRP3 inflammasome

(2019) Xuechan Huang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway

(2019) Qingqing Zhou et al.   ONCOGENE

The SGK1 inhibitor EMD638683, prevents Angiotensin II–induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation

(2018) Wenqiang Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury

(2018) Yuehui Zhang et al.   JOURNAL OF IMMUNOLOGY

Recruitment of macrophages from the spleen contributes to myocardial fibrosis and hypertension induced by angiotensin II

(2017) Ning-Ping Wang et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease

(2017) Honglei Guo et al.   MEDIATORS OF INFLAMMATION

The regulation of NLRP3 inflammasome expression during the development of cardiac contractile dysfunction in chronic kidney disease

(2017) Li-Han Chin et al.   Oncotarget

Involvement of Endoplasmic Reticulum Stress in Uremic Cardiomyopathy: Protective Effects of Tauroursodeoxycholic Acid

(2016) Wei Ding et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure

(2016) Alexandros Briasoulis et al.   HEART FAILURE REVIEWS

A Comprehensive Lifestyle Peer Group–Based Intervention on Cardiovascular Risk Factors

(2016) Emilia Gómez-Pardo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Role of Mitochondrial Functional Proteins in ROS Production in Ischemic Heart Diseases

(2016) Haifeng Pei et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

(2016) Wei Ding et al.   Oncotarget

Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension

(2015) Germán E. González et al.   JOURNAL OF HYPERTENSION

Apocynin attenuates oxidative stress and cardiac fibrosis in angiotensin II-induced cardiac diastolic dysfunction in mice

(2013) Yu-qiong Li et al.   ACTA PHARMACOLOGICA SINICA

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

(2013) Øystein Sandanger et al.   CARDIOVASCULAR RESEARCH

Targeting the renin–angiotensin–aldosterone system in heart failure

(2013) Chim C. Lang et al.   Nature Reviews Cardiology

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β

(2012) Nathan A. Bracey et al.   EXPERIMENTAL PHYSIOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Vascular Remodeling in Hypertension

(2011) Ernesto L. Schiffrin   HYPERTENSION

Ventricular Remodeling

(2011) James E. Udelson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

(2008) Mariana G. Rosca et al.   CARDIOVASCULAR RESEARCH

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production

(2008) Ivan Tattoli et al.   EMBO REPORTS