NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease

Involvement of Endoplasmic Reticulum Stress in Uremic Cardiomyopathy: Protective Effects of Tauroursodeoxycholic Acid

(2016) Wei Ding et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Loss of mitochondrial DNA–encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly

(2016) Sze Chern Lim et al.   FASEB JOURNAL

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

(2016) Wei Ding et al.   Oncotarget

The Future Burden of CKD in the United States: A Simulation Model for the CDC CKD Initiative

(2015) Thomas J. Hoerger et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Molecular Activation of the NLRP3 Inflammasome in Fibrosis: Common Threads Linking Divergent Fibrogenic Diseases

(2015) Carol M. Artlett et al.   ANTIOXIDANTS & REDOX SIGNALING

Tempol, a Superoxide Dismutase-Mimetic Drug, Ameliorates Progression of Renal Disease in CKD Mice

(2015) Wei Ding et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Rapamycin Attenuates Aldosterone-Induced Tubulointerstitial Inflammation and Fibrosis

(2015) Bin Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mechanisms linking mtDNA damage and aging

(2015) Milena Pinto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation

(2015) Wei Ding et al.   MEDICAL SCIENCE MONITOR

NLRP3 Inflammasome Activation in Dialyzed Chronic Kidney Disease Patients

(2015) Simona Granata et al.   PLoS One

NLRP3 Inflammasome Mediates Albumin-induced Renal Tubular Injury through Impaired Mitochondrial Function

(2014) Yibo Zhuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Genomic Annotation of Genetic Risk Loci Highlights Inflammation and Epithelial Biology Networks in CKD

(2014) N. Ledo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Contributions of Endoplasmic Reticulum Stress and Reactive Oxygen Species to Renal Injury in Aldosterone/Salt-Induced Rats

(2014) Chengyan Xu et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)

(2014) Daniela Impellizzeri et al.   PHARMACOLOGICAL RESEARCH

Nlrp3 Prevents Early Renal Interstitial Edema and Vascular Permeability in Unilateral Ureteral Obstruction

(2014) Wilco P. Pulskens et al.   PLoS One

ATP-P2X4 signaling mediates NLRP3 inflammasome activation: A novel pathway of diabetic nephropathy

(2013) Kehong Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Macrophage Phenotype Controls Long-Term AKI Outcomes--Kidney Regeneration versus Atrophy

(2013) M. Lech et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase

(2013) Masanori Tamaki et al.   KIDNEY INTERNATIONAL

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Improved Mitochondrial Function Underlies the Protective Effect of Pirfenidone against Tubulointerstitial Fibrosis in 5/6 Nephrectomized Rats

(2013) Jun-Feng Chen et al.   PLoS One

The Inflammasomes in Kidney Disease

(2011) H.-J. Anders et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease

(2009) Simona Granata et al.   BMC GENOMICS

IL-18 neutralization ameliorates obstruction-induced epithelial–mesenchymal transition and renal fibrosis

(2009) Ahmad H. Bani-Hani et al.   KIDNEY INTERNATIONAL

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

TMEM70 protein — A novel ancillary factor of mammalian ATP synthase

(2008) Josef Houštěk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS