Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

Challenges and Perspectives of DNA Nanostructures in Biomedicine

(2020) Adrian Keller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biophysical characterization of DNA origami nanostructures reveals inaccessibility to intercalation binding sites

(2020) Helen Miller et al.   NANOTECHNOLOGY

Global and local mechanical properties control endonuclease reactivity of a DNA origami nanostructure

(2020) Antonio Suma et al.   NUCLEIC ACIDS RESEARCH

Exceptional Nuclease Resistance of Paranemic Crossover (PX) DNA and Crossover-Dependent Biostability of DNA Motifs

(2020) Arun Richard Chandrasekaran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA origami protection and molecular interfacing through engineered sequence-defined peptoids

(2020) Shih-Ting Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Origami‐Enabled Engineering of Ligand–Drug Conjugates for Targeted Drug Delivery

(2020) Zhilei Ge et al.   Small

Robotic DNA Nanostructures

(2020) Sami Nummelin et al.   ACS Synthetic Biology

Framework nucleic acids as programmable carrier for transdermal drug delivery

(2019) Christian Wiraja et al.   Nature Communications

Reconfigurable DNA Origami Nanocapsule for pH-Controlled Encapsulation and Display of Cargo

(2019) Heini Ijäs et al.   ACS Nano

Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy

(2019) Saminathan Ramakrishnan et al.   CHEMBIOCHEM

Aptamer-Functionalized DNA Origami for Targeted Codelivery of Antisense Oligonucleotides and Doxorubicin to Enhance Therapy in Drug-Resistant Cancer Cells

(2019) Qingshan Pan et al.   ACS Applied Materials & Interfaces

Evolution of Structural DNA Nanotechnology

(2018) Sami Nummelin et al.   ADVANCED MATERIALS

On the Stability of DNA Origami Nanostructures in Low-Magnesium Buffers

(2018) Charlotte Kielar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A DNA-Based Nanocarrier for Efficient Gene Delivery and Combined Cancer Therapy

(2018) Jianbing Liu et al.   NANO LETTERS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Time-lapse live cell imaging to monitor doxorubicin release from DNA origami nanostructures

(2018) Yun Zeng et al.   Journal of Materials Chemistry B

DNA Nanostructures at the Interface with Biology

(2018) Katherine E. Bujold et al.   Chem

Plasmonic nanostructures through DNA-assisted lithography

(2018) Boxuan Shen et al.   Science Advances

Structural stability of DNA origami nanostructures under application-specific conditions

(2018) Saminathan Ramakrishnan et al.   Computational and Structural Biotechnology Journal

A Tailored DNA Nanoplatform for Synergistic RNAi-/Chemotherapy of Multidrug-Resistant Tumors

(2018) Jianbing Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

(2018) Dawei Jiang et al.   Nature Biomedical Engineering

Newly Synthesized Doxorubicin Complexes with Selected Metals—Synthesis, Structure and Anti-Breast Cancer Activity

(2017) Agata Jabłońska-Trypuć et al.   MOLECULES

Sculpting light by arranging optical components with DNA nanostructures

(2017) Mauricio Pilo-Pais et al.   MRS BULLETIN

DNA origami: The bridge from bottom to top

(2017) Anqin Xu et al.   MRS BULLETIN

Nanometrology and super-resolution imaging with DNA

(2017) Elton Graugnard et al.   MRS BULLETIN

DNA origami devices for molecular-scale precision measurements

(2017) Carlos E. Castro et al.   MRS BULLETIN

DNA Nanotechnology: A foundation for Programmable Nanoscale Materials

(2017) Mark Bathe et al.   MRS BULLETIN

DNA origami/gold nanorod hybrid nanostructures for the circumvention of drug resistance

(2017) Linlin Song et al.   Nanoscale

Binary control of enzymatic cleavage of DNA origami by structural antideterminants

(2017) Alex Stopar et al.   NUCLEIC ACIDS RESEARCH

Control of enzyme reactions by a reconfigurable DNA nanovault

(2017) Guido Grossi et al.   Nature Communications

Dynamic and Progressive Control of DNA Origami Conformation by Modulating DNA Helicity with Chemical Adducts

(2016) Haorong Chen et al.   ACS Nano

DNA-doxorubicin interaction: New insights and peculiarities

(2016) E. F. Silva et al.   BIOPOLYMERS

Automated design of DNA origami

(2016) Veikko Linko et al.   NATURE BIOTECHNOLOGY

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway

(2016) David H. Schaffert et al.   Small

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

(2015) Patrick D. Halley et al.   Small

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Addressing the Instability of DNA Nanostructures in Tissue Culture

(2014) Jaeseung Hahn et al.   ACS Nano

Nanopore Single-Molecule Analysis of DNA–Doxorubicin Interactions

(2014) Fujun Yao et al.   ANALYTICAL CHEMISTRY

Facile and Scalable Preparation of Pure and Dense DNA Origami Solutions

(2014) Evi Stahl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction of Doxorubicin with Polynucleotides. A Spectroscopic Study

(2014) Marta Airoldi et al.   BIOCHEMISTRY

New Insights into the Mechanism of the DNA/Doxorubicin Interaction

(2014) Cristina Pérez-Arnaiz et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A permeation method for detection of self-aggregation of doxorubicin in aqueous environment

(2013) Zoltán Fülöp et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

DNA nanostructure serum stability: greater than the sum of its parts

(2012) Justin W. Conway et al.   CHEMICAL COMMUNICATIONS

Early stage intercalation of doxorubicin to DNA fragments observed in molecular dynamics binding simulations

(2012) Hongxing Lei et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

Quantitative prediction of 3D solution shape and flexibility of nucleic acid nanostructures

(2011) Do-Nyun Kim et al.   NUCLEIC ACIDS RESEARCH

Determining association constants from titration experiments in supramolecular chemistry

(2010) Pall Thordarson   CHEMICAL SOCIETY REVIEWS

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

NUPACK: Analysis and design of nucleic acid systems

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

Large-area spatially ordered arrays of gold nanoparticles directed by lithographically confined DNA origami

(2009) Albert M. Hung et al.   Nature Nanotechnology

Rapid prototyping of 3D DNA-origami shapes with caDNAno

(2009) Shawn M. Douglas et al.   NUCLEIC ACIDS RESEARCH