Genetic variation, brain, and intelligence differences

Education, intelligence and Alzheimer’s disease: evidence from a multivariable two-sample Mendelian randomization study

(2020) Emma L Anderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

DNA methylation and brain structure and function across the life course: a systematic review

(2020) Emily N.W. Wheater et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The effect of network thresholding and weighting on structural brain networks in the UK Biobank

(2020) Colin R. Buchanan et al.   NEUROIMAGE

Cognitive ability and education: How behavioural genetic research has advanced our knowledge and understanding of their association

(2020) Margherita Malanchini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

(2020) Ben Brumpton et al.   Nature Communications

Brain connections derived from diffusion MRI tractography can be highly anatomically accurate—if we know where white matter pathways start, where they end, and where they do not go

(2020) Kurt G. Schilling et al.   Brain Structure & Function

A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data

(2020) Javier de la Fuente et al.   Nature Human Behaviour

Thickness of the cerebral cortex shows positive association with blood levels of triacylglycerols carrying 18-carbon fatty acids

(2020) Eeva Sliz et al.   Communications Biology

Coupled cognitive changes in adulthood: A meta-analysis.

(2019) Elliot M. Tucker-Drob et al.   PSYCHOLOGICAL BULLETIN

Associations between vascular risk factors and brain MRI indices in UK Biobank

(2019) Simon R Cox et al.   EUROPEAN HEART JOURNAL

Mendelian randomization: the challenge of unobserved environmental confounds

(2019) Philipp D Koellinger et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic correlations of polygenic disease traits: from theory to practice

(2019) Wouter van Rheenen et al.   NATURE REVIEWS GENETICS

Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer’s Coordinating Center Uniform Data Set

(2019) Christian Puzo et al.   Alzheimers Research & Therapy

Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

(2019) Susana Muñoz Maniega et al.   Frontiers in Neurology

Brain Peak Width of Skeletonized Mean Diffusivity (PSMD) and Cognitive Function in Later Life

(2019) Ian J. Deary et al.   Frontiers in Psychiatry

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

(2019) Andrew D. Grotzinger et al.   Nature Human Behaviour

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

(2019) Max Lam et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706)

(2019) Bingxin Zhao et al.   MOLECULAR PSYCHIATRY

Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

(2019) Bingxin Zhao et al.   NATURE GENETICS

Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936

(2019) Janie Corley et al.   Translational Psychiatry

Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence

(2019) Tristram A Lett et al.   CEREBRAL CORTEX

An epigenetic predictor of death captures multi-modal measures of brain health

(2019) Robert F. Hillary et al.   MOLECULAR PSYCHIATRY

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

(2019) Tianye Jia et al.   MOLECULAR PSYCHIATRY

Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

(2019) W. David Hill et al.   Nature Communications

Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants

(2018) Stuart J Ritchie et al.   CEREBRAL CORTEX

Bias in Mendelian randomization due to assortative mating

(2018) Fernando Pires Hartwig et al.   GENETIC EPIDEMIOLOGY

Genomic analysis of family data reveals additional genetic effects on intelligence and personality

(2018) W. David Hill et al.   MOLECULAR PSYCHIATRY

Meta-analysis of epigenome-wide association studies of cognitive abilities

(2018) Riccardo E. Marioni et al.   MOLECULAR PSYCHIATRY

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

(2018) Jonathan R. I. Coleman et al.   MOLECULAR PSYCHIATRY

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

(2018) W. D. Hill et al.   MOLECULAR PSYCHIATRY

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits

(2018) Luke M. Evans et al.   NATURE GENETICS

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

(2018) Jeanne E. Savage et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

The new genetics of intelligence

(2018) Robert Plomin et al.   NATURE REVIEWS GENETICS

Definition and characterization of an extended multiple-demand network

(2018) J.A. Camilleri et al.   NEUROIMAGE

Morphometric Similarity Networks Detect Microscale Cortical Organization and Predict Inter-Individual Cognitive Variation

(2018) Jakob Seidlitz et al.   NEURON

Normative brain size variation and brain shape diversity in humans

(2018) P. K. Reardon et al.   SCIENCE

The nature of nurture: Effects of parental genotypes

(2018) Augustine Kong et al.   SCIENCE

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

(2018) Gail Davies et al.   Nature Communications

Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence

(2018) Erhan Genç et al.   Nature Communications

Unique mapping of structural and functional connectivity on cognition

(2018) J. Zimmermann et al.   JOURNAL OF NEUROSCIENCE

Relatedness disequilibrium regression estimates heritability without environmental bias

(2018) Alexander I. Young et al.   NATURE GENETICS

A distributed brain network predicts general intelligence from resting-state human neuroimaging data

(2018) Julien Dubois et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood

(2018) Gilad Twig et al.   Cardiovascular Diabetology

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

(2017) J W Trampush et al.   MOLECULAR PSYCHIATRY

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

(2017) Suzanne Sniekers et al.   NATURE GENETICS

Childhood intelligence in relation to major causes of death in 68 year follow-up: prospective population study

(2017) Catherine M Calvin et al.   BMJ-British Medical Journal

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

(2017) Esperanza Fernández et al.   Cell Reports

Childhood intelligence in relation to major causes of death in 68 year follow-up: prospective population study

(2017) Catherine M Calvin et al.   BMJ-British Medical Journal

Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank

(2016) W. David Hill et al.   CURRENT BIOLOGY

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

(2016) G Davies et al.   MOLECULAR PSYCHIATRY

A watershed model of individual differences in fluid intelligence

(2016) Rogier A. Kievit et al.   NEUROPSYCHOLOGIA

Ageing and brain white matter structure in 3,513 UK Biobank participants

(2016) Simon R. Cox et al.   Nature Communications

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

(2015) Zhihong Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Brain volumetric changes and cognitive ageing during the eighth decade of life

(2015) Stuart J. Ritchie et al.   HUMAN BRAIN MAPPING

Coupled Changes in Brain White Matter Microstructure and Fluid Intelligence in Later Life

(2015) S. J. Ritchie et al.   JOURNAL OF NEUROSCIENCE

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

(2015) G Davies et al.   MOLECULAR PSYCHIATRY

Meta-analysis of the heritability of human traits based on fifty years of twin studies

(2015) Tinca J C Polderman et al.   NATURE GENETICS

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

(2015) Michael R Johnson et al.   NATURE NEUROSCIENCE

Meta-analysis of associations between human brain volume and intelligence differences: How strong are they and what do they mean?

(2015) Jakob Pietschnig et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Changes in Thickness and Surface Area of the Human Cortex and Their Relationship with Intelligence

(2014) H. G. Schnack et al.   CEREBRAL CORTEX

Influence of Gene Interaction on Complex Trait Variation with Multilocus Models

(2014) Asko Mäki-Tanila et al.   GENETICS

Subcortical intelligence: Caudate volume predicts IQ in healthy adults

(2014) Rachael G. Grazioplene et al.   HUMAN BRAIN MAPPING

Testing the key assumption of heritability estimates based on genome-wide genetic relatedness

(2014) Dalton Conley et al.   JOURNAL OF HUMAN GENETICS

Genetics and intelligence differences: five special findings

(2014) R Plomin et al.   MOLECULAR PSYCHIATRY

Neuroanatomical Correlates of Intelligence in Healthy Young Adults: The Role of Basal Ganglia Volume

(2014) Cosima Rhein et al.   PLoS One

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

(2014) C. A. Rietveld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus

(2014) Anders M. Fjell et al.   PROGRESS IN NEUROBIOLOGY

Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking

(2014) Rogier A. Kievit et al.   Nature Communications

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

(2014) W D Hill et al.   Translational Psychiatry

Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age

(2013) S Karama et al.   MOLECULAR PSYCHIATRY

Cognitive ability changes and dynamics of cortical thickness development in healthy children and adolescents

(2013) Miguel Burgaleta et al.   NEUROIMAGE

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Executive Functions

(2012) Adele Diamond   Annual Review of Psychology

An integrative architecture for general intelligence and executive function revealed by lesion mapping

(2012) A. K. Barbey et al.   BRAIN

Brain white matter tract integrity as a neural foundation for general intelligence

(2012) L Penke et al.   MOLECULAR PSYCHIATRY

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

(2012) G Davies et al.   MOLECULAR PSYCHIATRY

White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI

(2012) Derek K. Jones et al.   NEUROIMAGE

Intelligence

(2011) Ian J. Deary   Annual Review of Psychology

APOE E4 status predicts age-related cognitive decline in the ninth decade: longitudinal follow-up of the Lothian Birth Cohort 1921

(2011) O J G Schiepers et al.   MOLECULAR PSYCHIATRY

Genome-wide association studies establish that human intelligence is highly heritable and polygenic

(2011) G Davies et al.   MOLECULAR PSYCHIATRY

Genetic influences on cognitive functions in the elderly: A selective review of twin studies

(2010) Teresa Lee et al.   BRAIN RESEARCH REVIEWS

Hippocampal-anterior thalamic pathways for memory: uncovering a network of direct and indirect actions

(2010) John P. Aggleton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Intellectual abilities and white matter microstructure in development: A diffusion tensor imaging study

(2010) Christian K. Tamnes et al.   HUMAN BRAIN MAPPING

Selective review of cognitive aging

(2010) TIMOTHY A. SALTHOUSE   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

The neuroscience of human intelligence differences

(2010) Ian J. Deary et al.   NATURE REVIEWS NEUROSCIENCE

Where in-vivo imaging meets cytoarchitectonics: The relationship between cortical thickness and neuronal density measured with high-resolution [18F]flumazenil-PET

(2010) Christian la Fougère et al.   NEUROIMAGE

Distributed neural system for general intelligence revealed by lesion mapping

(2010) J. Glascher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The heritability of general cognitive ability increases linearly from childhood to young adulthood

(2009) C M A Haworth et al.   MOLECULAR PSYCHIATRY

Heritability in the genomics era — concepts and misconceptions

(2008) Peter M. Visscher et al.   NATURE REVIEWS GENETICS