Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

(2019) Richard Karlsson Linnér et al.   NATURE GENETICS

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

(2019) Philip R. Jansen et al.   NATURE GENETICS

Genetic Markers of ADHD-Related Variations in Intracranial Volume

(2019) Marieke Klein et al.   AMERICAN JOURNAL OF PSYCHIATRY

A global overview of pleiotropy and genetic architecture in complex traits

(2019) Kyoko Watanabe et al.   NATURE GENETICS

Heritability of Regional Brain Volumes in Large-Scale Neuroimaging and Genetic Studies

(2018) Bingxin Zhao et al.   CEREBRAL CORTEX

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

(2018) W. D. Hill et al.   MOLECULAR PSYCHIATRY

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

(2018) Jeanne E. Savage et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

(2018) Alexander Gusev et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Harmonization of cortical thickness measurements across scanners and sites

(2018) Jean-Philippe Fortin et al.   NEUROIMAGE

Statistical Challenges in “Big Data” Human Neuroimaging

(2018) Stephen M. Smith et al.   NEURON

GWAS on family history of Alzheimer’s disease

(2018) Riccardo E. Marioni et al.   Translational Psychiatry

The Lifespan Human Connectome Project in Development: A large-scale study of brain connectivity development in 5–21 year olds

(2018) Leah H. Somerville et al.   NEUROIMAGE

The relationship of IQ and emotional processing with insula volume in schizophrenia

(2018) Alice Caldiroli et al.   SCHIZOPHRENIA RESEARCH

Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes

(2018) Dennis van der Meer et al.   MOLECULAR PSYCHIATRY

Genome-wide association studies of brain imaging phenotypes in UK Biobank

(2018) Lloyd T. Elliott et al.   NATURE

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

The relationship between brain volumes and intelligence in bipolar disorder

(2017) Annabel Vreeker et al.   JOURNAL OF AFFECTIVE DISORDERS

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

(2017) Michelle Luciano et al.   NATURE GENETICS

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

(2017) Zhiqiang Li et al.   NATURE GENETICS

Concepts, estimation and interpretation of SNP-based heritability

(2017) Jian Yang et al.   NATURE GENETICS

Genetic architecture: the shape of the genetic contribution to human traits and disease

(2017) Nicholas J. Timpson et al.   NATURE REVIEWS GENETICS

Novel genetic loci associated with hippocampal volume

(2017) Derrek P. Hibar et al.   Nature Communications

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766)

(2017) E M Wigmore et al.   Translational Psychiatry

Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex

(2016) Tulio Guadalupe et al.   Brain Imaging and Behavior

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

(2016) G Davies et al.   MOLECULAR PSYCHIATRY

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

(2016) Barbara Franke et al.   NATURE NEUROSCIENCE

Gene expression elucidates functional impact of polygenic risk for schizophrenia

(2016) Menachem Fromer et al.   NATURE NEUROSCIENCE

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

(2016) Karla L Miller et al.   NATURE NEUROSCIENCE

Removing inter-subject technical variability in magnetic resonance imaging studies

(2016) Jean-Philippe Fortin et al.   NEUROIMAGE

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

(2016) Terry L. Jernigan et al.   NEUROIMAGE

A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome

(2016) Anthony D. Schmitt et al.   Cell Reports

XWAS: A Software Toolset for Genetic Data Analysis and Association Studies of the X Chromosome

(2015) Feng Gao et al.   JOURNAL OF HEREDITY

A novel Alzheimer disease locus located near the gene encoding tau protein

(2015) G Jun et al.   MOLECULAR PSYCHIATRY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Common genetic variants influence human subcortical brain structures

(2015) Derrek P. Hibar et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

What Twin Studies Tell Us About the Heritability of Brain Development, Morphology, and Function: A Review

(2015) Arija G. Jansen et al.   NEUROPSYCHOLOGY REVIEW

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke

(2015) Ken B. Hanscombe et al.   STROKE

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Genomic architecture of human neuroanatomical diversity

(2014) R Toro et al.   MOLECULAR PSYCHIATRY

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements

(2014) Nicholas J. Tustison et al.   NEUROIMAGE

The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

(2013) Michael W. Weiner et al.   Alzheimers & Dementia

Conceptual and Data-based Investigation of Genetic Influences and Brain Asymmetry: A Twin Study of Multiple Structural Phenotypes

(2013) Lisa T. Eyler et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Heritability of subcortical brain measures: A perspective for future genome-wide association studies

(2013) Anouk den Braber et al.   NEUROIMAGE

Neuroimaging of the Philadelphia Neurodevelopmental Cohort

(2013) Theodore D. Satterthwaite et al.   NEUROIMAGE

Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects

(2012) Derrek P. Hibar et al.   Brain Imaging and Behavior

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume

(2012) M Arfan Ikram et al.   NATURE GENETICS

Common variants at 12q14 and 12q24 are associated with hippocampal volume

(2012) et al.   NATURE GENETICS

Identification of common variants associated with human hippocampal and intracranial volumes

(2012) Jason L Stein et al.   NATURE GENETICS

FreeSurfer

(2012) Bruce Fischl   NEUROIMAGE

White matter integrity as an intermediate phenotype: Exploratory genome-wide association analysis in individuals at high risk of bipolar disorder

(2012) Emma Sprooten et al.   PSYCHIATRY RESEARCH

Genetic and Environmental Influences on Neuroimaging Phenotypes: A Meta-Analytical Perspective on Twin Imaging Studies

(2012) Gabriëlla A. M. Blokland et al.   Twin Research and Human Genetics

WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk

(2012) Hou-Feng Zheng et al.   PLoS Genetics

Genome-wide association study of Alzheimer's disease

(2012) M I Kamboh et al.   Translational Psychiatry

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Genetic and environmental influences on structural variability of the brain in pediatric twin: Deformation based morphometry

(2011) Uicheul Yoon et al.   NEUROSCIENCE LETTERS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders

(2010) S Kim et al.   MOLECULAR PSYCHIATRY

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

(2010) S J Furney et al.   MOLECULAR PSYCHIATRY

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

A reproducible evaluation of ANTs similarity metric performance in brain image registration

(2010) Brian B. Avants et al.   NEUROIMAGE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study

(2009) William S. Kremen et al.   NEUROIMAGE

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

(2008) Sergio E. Baranzini et al.   HUMAN MOLECULAR GENETICS